Dataset

Association of rs2046210 and rs12662670 with risk of ER−*/ER+** breast cancer.

public-library-of-science,

2012

DOI:10.1371/journal.pone.0042380.t003, Dimensions: 267511,

Authors

Affiliations

Organisations

  1. (1) University of Melbourne, grid.1008.9
  2. (2) National Institute for Public Health and the Environment, grid.31147.30
  3. (3) Institute of Cancer Research, grid.18886.3f
  4. (4) National Institute for Health Research, grid.451056.3
  5. (5) Heidelberg University, grid.7700.0
  6. (6) University of Copenhagen, grid.5254.6, KU
  7. (7) Hospital Monte Naranco, grid.414858.4
  8. (8) Hospital Universitario La Paz, grid.81821.32
  9. (9) Hannover Medical School, grid.10423.34
  10. (10) Institute of Biochemistry and Genetics of Ufa Scientific Centre, grid.429129.5
  11. (11) Karolinska Institute, grid.4714.6
  12. (12) Oslo University Hospital, grid.55325.34
  13. (13) Erasmus University Medical Center, grid.5645.2
  14. (14) Pomeranian Medical University, grid.107950.a

Description

Results are presented overall as well as separately for Europeans and Asians. Pooled analyses adjusted for the studies were performed. A log-additive genetic model was assumed.*Estrogen receptor negative.**Estrogen receptor positive.aOdds ratio per minor allele (A allele for rs2046210, G allele for rs12662670) derived from case-control logistic regression restricted to ER+ or ER− cases, respectively, and the whole control sample.bP-value derived from the log-additive model derived from case-control logistic regression restricted to ER+ or ER− cases, respectively, and the whole control sample.cP-value for heterogeneity between estimates of genetic main effects derived from case-only analysis.