Dataset

Conditional associations for BRCA1 and BRCA2 top SNPs.

public-library-of-science,

2016

DOI:10.1371/journal.pone.0158801.t003, Dimensions: 3882828,

Authors

Affiliations

Organisations

  1. (1) Sheffield Children's Hospital, grid.413991.7
  2. (2) Pomeranian Medical University, grid.107950.a
  3. (3) University of Cambridge, grid.5335.0
  4. (4) Memorial Sloan Kettering Cancer Center, grid.51462.34
  5. (5) University of Würzburg, grid.8379.5
  6. (6) City Of Hope National Medical Center, grid.410425.6
  7. (7) University Hospital Heidelberg, grid.5253.1
  8. (8) Istituto Oncologico Veneto, grid.419546.b

Description

The table shows the HR estimate. 95% CI and p-value for the conditional analysis adjusting for the lead SNP in the univariate analysis for BRCA1 (left hand side) or BRCA2 mutation carriers (right had side). SNPs correspond to: rs10124837, the strongest associated in BRCA1; rs62543583, the strongest associated in BRCA2 mutation carriers; rs7046326, the strongest associated in BRCA1/2 meta-analysis; rs3814113, was the strongest associated variant in the initial GWAS analysis. “HR”, hazard ratio; “CI”, confidence interval.

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Licence

CC BY 4.0

External sources

Access at Figshare