Article

Excess Early Mortality in Schizophrenia

Annual Review of Clinical Psychology, Annual Reviews, ISSN 1548-5943

Volume 10, 1, 2014

DOI:10.1146/annurev-clinpsy-032813-153657, Dimensions: pub.1008345396, PMID: 24313570,

Affiliations

Organisations

  1. (1) Lundbeck Foundation, grid.452548.a
  2. (2) Aarhus University, grid.7048.b, AU
  3. (3) University of Copenhagen, grid.5254.6, KU

Countries

Denmark

Continents

Europe

Description

Schizophrenia is often referred to as one of the most severe mental disorders, primarily because of the very high mortality rates of those with the disorder. This article reviews the literature on excess early mortality in persons with schizophrenia and suggests reasons for the high mortality as well as possible ways to reduce it. Persons with schizophrenia have an exceptionally short life expectancy. High mortality is found in all age groups, resulting in a life expectancy of approximately 20 years below that of the general population. Evidence suggests that persons with schizophrenia may not have seen the same improvement in life expectancy as the general population during the past decades. Thus, the mortality gap not only persists but may actually have increased. The most urgent research agenda concerns primary candidates for modifiable risk factors contributing to this excess mortality, i.e., side effects of treatment and lifestyle factors, as well as sufficient prevention and treatment of physical comorbidity.

Research Categories

Main Subject Area

Sustainable Development Goals

Links & Metrics

NORA University Profiles

Aarhus University

University of Copenhagen

Dimensions Citation Indicators

Times Cited: 260

Field Citation Ratio (FCR): 55.38

Relative Citation ratio (RCR): 12.99