Article open access publication

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

Nature Genetics, Springer Nature, ISSN 1061-4036

Volume 45, 4, 2013

DOI:10.1038/ng.2566, Dimensions: pub.1022170805, PMC: PMC3670748, PMID: 23535731,

Authors

Bojesen, Stig E * (1) (2)
Lu, Yi (4)
Weischer, Maren (1) (2)
Nielsen, Sune F (1) (2)
Wang, Qin (3)
Rossing, Mary Anne (15) (16)
Guénel, Pascal (28) (29)
Burwinkel, Barbara (21) (31)
Marme, Frederik (31) (32)
Hein, Rebecca (21) (33)
Andrulis, Irene L (36) (37)
Giles, Graham G (39) (40) (41)
Fasching, Peter A (25) (44)
Radice, Paolo (45) (46)
Brauch, Hiltrud (49) (50)
Winqvist, Robert (52) (53)
Mannermaa, Arto (57) (58)
Butzow, Ralf (24) (59)
Zheng, Wei (60)
Muir, Kenneth (66) (67)
Heitz, Florian (70) (71)
du Bois, Andreas (70) (71)
Harter, Philipp (70) (71)
Teo, Soo-Hwang (73) (74)
Blot, William (60) (76)
Hartman, Mikael (20) (79)
Høgdall, Estrid (81) (85)
Shen, Chen-Yang (86) (87)
Poole, Elizabeth M (94) (96)
Salvesen, Helga B (100) (101)
Wik, Elisabeth (100) (101)
Brouwers, Barbara (12) (102)
Krakstad, Camilla (100) (101)
Wauters, Els (26) (27)
Halle, Mari K (100) (101)
Kiemeney, Lambertus A (103) (104)
Aben, Katja K (103) (104)
Truong, Thérèse (28) (29)
Benitez, Javier (14) (106)
Kelemen, Linda E (111) (112)
Le, Nhu D (113)
Brooks-Wilson, Angela (113) (114)
Knight, Julia A (37) (120)
Gore, Martin (121)
Jager, Agnes (122)
Paul, James (124)
Severi, Gianluca (39) (41)
Baglietto, Laura (39) (41)
Sieh, Weiva (126)
Gao, Yu-Tang (129)
Goldberg, Mark S (130) (131)
Yang, Gong (60)
McLaughlin, John R (37) (118)
Ficarazzi, Filomena (45) (135)
Orr, Nick (47)
Menon, Usha (137)
Pike, Malcolm C (8) (90)
Pylkäs, Katri (52) (53)
Jaworska, Katarzyna (56) (143)
Kosma, Veli-Matti (57) (58)
Ditsch, Nina (146)
Cai, Hui (60)
Lu, Wei (149)
Signorello, Lisa B (60) (76)
Miao, Hui (79)
Peterlongo, Paolo (45) (46)
Rebbeck, Timothy R (156) (157)
Garber, Judy (165)
Olah, Edith (167)
Arun, Banu K (174)
Walker, Lisa (183)
Cole, Trevor (186)
Faivre, Laurence (189) (190)
Frenay, Marc (191)
Sinilnikova, Olga M (188) (192)
Bonadona, Valérie (193) (194)
Bernard, Loris (135) (136)
Borg, Åke (201)
Domchek, Susan M (156) (157)
Salani, Ritu (150)
Dicks, Ed (3)
Lakhani, Sunil R (5) (211)
Hall, Per (20)
Reddel, Roger R (6) (7)

* Corresponding author

Affiliations

Organisations

  1. (1) Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark
  2. (2) Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark
  3. (3) University of Cambridge, grid.5335.0
  4. (4) QIMR Berghofer Medical Research Institute, grid.1049.c
  5. (5) University of Queensland, grid.1003.2
  6. (6) Children's Medical Research Institute, grid.414235.5
  7. (7) University of Sydney, grid.1013.3
  8. (8) University of Southern California, grid.42505.36
  9. (9) National Cancer Institute, grid.48336.3a
  10. (10) Moffitt Cancer Center, grid.468198.a
  11. (11) McGill University and Génome Québec Innovation Centre, grid.411640.6
  12. (12) Universitair Ziekenhuis Leuven, grid.410569.f
  13. (13) Yale University, grid.47100.32
  14. (14) Spanish National Cancer Research Centre, grid.7719.8
  15. (15) Fred Hutchinson Cancer Research Center, grid.270240.3
  16. (16) University of Washington, grid.34477.33
  17. (17) Dartmouth College, grid.254880.3
  18. (18) Mayo Clinic, grid.66875.3a
  19. (19) University of Kansas Cancer Center, grid.468219.0
  20. (20) Karolinska Institute, grid.4714.6
  21. (21) German Cancer Research Center, grid.7497.d
  22. (22) London School of Hygiene & Tropical Medicine, grid.8991.9
  23. (23) Antoni van Leeuwenhoek Hospital, grid.430814.a
  24. (24) Department of Obstetrics and Gynecology, Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland
  25. (25) University of California, Los Angeles, grid.19006.3e
  26. (26) Flanders Institute for Biotechnology, grid.11486.3a
  27. (27) KU Leuven, grid.5596.f
  28. (28) Institut National de la Santé et de la Recherche Médicale (INSERM) U1018, CESP (Center for Research in Epidemiology and Population Health), Environmental Epidemiology of Cancer, Villejuif, France
  29. (29) University of Paris-Sud, grid.5842.b
  30. (30) University of Sheffield, grid.11835.3e
  31. (31) Heidelberg University, grid.7700.0
  32. (32) National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany
  33. (33) University of Cologne, grid.6190.e
  34. (34) King's College London, grid.13097.3c
  35. (35) University of Ulm, grid.6582.9
  36. (36) Ontario Cancer Genetics Network, Fred A. Litwin Center for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
  37. (37) University of Toronto, grid.17063.33
  38. (38) Roswell Park Cancer Institute, grid.240614.5
  39. (39) University of Melbourne, grid.1008.9
  40. (40) Monash University, grid.1002.3
  41. (41) Cancer Council Victoria, grid.3263.4
  42. (42) Centre Hospitalier Universitaire de Québec, grid.411081.d
  43. (43) University of Hawaii at Manoa, grid.410445.0
  44. (44) University Hospital Erlangen, grid.411668.c
  45. (45) Istituto Fondazione Italiana per la Ricerca sul Cancro di Oncologia Molecolare, Milan, Italy
  46. (46) Fondazione IRCCS Istituto Nazionale dei Tumori, grid.417893.0
  47. (47) Institute of Cancer Research, grid.18886.3f
  48. (48) Cedars-Sinai Medical Center, grid.50956.3f
  49. (49) Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, grid.502798.1
  50. (50) University of Tübingen, grid.10392.39
  51. (51) Hannover Medical School, grid.10423.34
  52. (52) Department of Clinical Genetics, Laboratory of Cancer Genetics and Tumor Biology, University of Oulu, Oulu University Hospital, Oulu, Finland
  53. (53) University of Oulu, grid.10858.34
  54. (54) Jena University Hospital, grid.275559.9
  55. (55) Leiden University Medical Center, grid.10419.3d
  56. (56) Pomeranian Medical University, grid.107950.a
  57. (57) Kuopio University Hospital, grid.410705.7
  58. (58) University of Eastern Finland, grid.9668.1
  59. (59) Helsinki University Central Hospital, grid.15485.3d
  60. (60) Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
  61. (61) University of California, Irvine, grid.266093.8
  62. (62) University of Pittsburgh, grid.21925.3d
  63. (63) Oslo University Hospital, grid.55325.34
  64. (64) University of Oslo, grid.5510.1
  65. (65) The University of Texas Health Science Center at Houston, grid.267308.8
  66. (66) University of Manchester, grid.5379.8
  67. (67) University of Warwick, grid.7372.1
  68. (68) Maggee Women's Hospital, Pittsburgh, Pennsylvania, USA
  69. (69) Department of Gynecology and Obstetrics, Division of Tumor Genetics, Klinikum Rechts der Isar, Technical University Munich, Munich, Germany
  70. (70) Helios Dr. Horst Schmidt Kliniken Wiesbaden, grid.491861.3
  71. (71) Kliniken Essen-Mitte, grid.461714.1
  72. (72) Aichi Cancer Center, grid.410800.d
  73. (73) Cancer Research Initiatives Foundation, Sime Darby Medical Centre, Subang Jaya, Malaysia
  74. (74) University Malaya Medical Centre, grid.413018.f
  75. (75) Institut für Humangenetik Wiesbaden, Wiesbaden, Germany
  76. (76) International Epidemiology Institute, grid.419344.f
  77. (77) Seoul National University, grid.31501.36
  78. (78) Okazaki City Hospital, grid.413724.7
  79. (79) National University of Singapore, grid.4280.e
  80. (80) National Cancer Institute of Thailand, grid.419173.9
  81. (81) Danish Cancer Society, grid.417390.8
  82. (82) Rigshospitalet, grid.475435.4, Capital Region
  83. (83) International Agency For Research On Cancer, grid.17703.32
  84. (84) Faculty of Medicine, University of Southampton, University Hospital Southampton, Southampton, UK
  85. (85) University of Copenhagen, grid.5254.6, KU
  86. (86) China Medical University, grid.254145.3
  87. (87) Institute of Biomedical Sciences, Academia Sinica, grid.482251.8
  88. (88) Department of Obstetrics and Gynaecology, Faculty of Medicine, University Malaya Medical Centre, University Malaya, Kuala Lumpur, Malaysia
  89. (89) Department of Breast Surgery, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Denmark
  90. (90) Memorial Sloan Kettering Cancer Center, grid.51462.34
  91. (91) Duke University Hospital, grid.189509.c
  92. (92) University Medical Center Hamburg-Eppendorf, grid.13648.38
  93. (93) Duke University, grid.26009.3d
  94. (94) Harvard University, grid.38142.3c
  95. (95) Sanquin, grid.417732.4
  96. (96) Brigham and Women's Hospital, grid.62560.37
  97. (97) Genome Institute of Singapore, grid.418377.e
  98. (98) Rutgers, The State University of New Jersey, grid.430387.b
  99. (99) Department of Clinical Genetics, Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland
  100. (100) Haukeland University Hospital, grid.412008.f
  101. (101) University of Bergen, grid.7914.b
  102. (102) Department of Oncology, Laboratory of Experimental Oncology, Leuven, KU Leuven, Belgium
  103. (103) Comprehensive Cancer Center The Netherlands, Utrecht, The Netherlands
  104. (104) Radboud University Nijmegen Medical Centre, grid.10417.33
  105. (105) French Institute of Health and Medical Research, grid.7429.8
  106. (106) Centre for Biomedical Network Research on Rare Diseases, grid.452372.5
  107. (107) Oregon Health & Science University, grid.5288.7
  108. (108) Hospital Monte Naranco, grid.414858.4
  109. (109) Hospital Universitario La Paz, grid.81821.32
  110. (110) University of New Mexico, grid.266832.b
  111. (111) Alberta Health Services, grid.413574.0
  112. (112) University of Calgary, grid.22072.35
  113. (113) BC Cancer Agency, grid.248762.d
  114. (114) Simon Fraser University, grid.61971.38
  115. (115) University of Oxford, grid.4991.5
  116. (116) National University of Ireland, Galway, grid.6142.1
  117. (117) University Health Network, grid.231844.8
  118. (118) Lunenfeld-Tanenbaum Research Institute, grid.250674.2
  119. (119) Department of Radiation Oncology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
  120. (120) Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
  121. (121) Royal Marsden Hospital, grid.424926.f
  122. (122) Erasmus University Medical Center, grid.5645.2
  123. (123) Imperial College London, grid.7445.2
  124. (124) Beatson West of Scotland Cancer Centre, grid.422301.6
  125. (125) Glasgow Royal Infirmary, grid.411714.6
  126. (126) Stanford University, grid.168010.e
  127. (127) Krebsregister Saarland, grid.482902.5
  128. (128) University of Montreal, grid.14848.31
  129. (129) Shanghai Cancer Institute, grid.419087.3
  130. (130) McGill University, grid.14709.3b
  131. (131) Royal Victoria Hospital, grid.416229.a
  132. (132) Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander University Erlangen–Nuremberg, Erlangen, Germany
  133. (133) University of Erlangen-Nuremberg, grid.5330.5
  134. (134) Department of Preventive and Predictive Medicine, Unit of Medical Genetics, Fondazione IRCCS INT, Milan, Italy
  135. (135) Cogentech Cancer Genetic Test Laboratory, Milan, Italy
  136. (136) European Institute of Oncology, grid.15667.33
  137. (137) Gynaecological Cancer Research Centre, University College London Elizabeth Garrett Anderson Institute for Women's Health, London, UK
  138. (138) Ruhr University Bochum, grid.5570.7
  139. (139) Department of Internal Medicine, Evangelische Kliniken Bonn, Johanniter Krankenhaus, Bonn, Germany
  140. (140) Maria Skłodowska-Curie Memorial Cancer Center and Institute of Oncology, grid.418165.f
  141. (141) Department of Oncology, Oulu University Hospital, University of Oulu, Oulu, Finland
  142. (142) Department of Pathology, Oulu University Hospital, University of Oulu, Oulu, Finland
  143. (143) Medical University of Warsaw, grid.13339.3b
  144. (144) N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk, Belarus
  145. (145) Ministry of Public Health, grid.415836.d
  146. (146) Ludwig Maximilian University of Munich, grid.5252.0
  147. (147) Technical University of Munich, grid.6936.a
  148. (148) University Hospital Cologne, grid.411097.a
  149. (149) Shanghai Center for Disease Control and Prevention, Shanghai, China
  150. (150) The Ohio State University, grid.261331.4
  151. (151) Aristotle University of Thessaloniki, grid.4793.9
  152. (152) Tri-Service General Hospital, grid.278244.f
  153. (153) Kaohsiung Medical University Chung-Ho Memorial Hospital, grid.412027.2
  154. (154) Paris Descartes University, grid.10992.33
  155. (155) Institute Curie, grid.418596.7
  156. (156) Basser Research Center, Abramson Cancer Center, The University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA
  157. (157) University of Pennsylvania, grid.25879.31
  158. (158) Medical University of Vienna, grid.22937.3d
  159. (159) Sheba Medical Center, grid.413795.d
  160. (160) Odense University Hospital, grid.7143.1, Southern Denmark Region
  161. (161) Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
  162. (162) City Of Hope National Medical Center, grid.410425.6
  163. (163) University of Delaware, grid.33489.35
  164. (164) Genetic Counseling Unit, Hereditary Cancer Program, l'Institut d'Investigació Biomèdica de Bellvitge–Catalan Institute of Oncology, Barcelona, Spain
  165. (165) Dana-Farber Cancer Institute, grid.65499.37
  166. (166) Istituto Oncologico Veneto, grid.419546.b
  167. (167) National Institute of Oncology, grid.419617.c
  168. (168) University of Kansas Medical Center, grid.412016.0
  169. (169) National Centre of Scientific Research Demokritos, grid.6083.d
  170. (170) University of Utah, grid.223827.e
  171. (171) Hospital Clínico San Carlos, grid.411068.a
  172. (172) Institute of Oncology NN Petrov, grid.465337.0
  173. (173) Latvian Biomedical Research and Study Centre, grid.419210.f
  174. (174) The University of Texas MD Anderson Cancer Center, grid.240145.6
  175. (175) Peter MacCallum Cancer Centre, grid.1055.1
  176. (176) Maastricht University Medical Centre, grid.412966.e
  177. (177) VU University Medical Center, grid.16872.3a
  178. (178) University Medical Center Groningen, grid.4494.d
  179. (179) University Medical Center Utrecht, grid.7692.a
  180. (180) Academic Medical Center, grid.5650.6
  181. (181) Manchester University NHS Foundation Trust, grid.498924.a
  182. (182) University Hospitals of Leicester NHS Trust, grid.269014.8
  183. (183) Churchill Hospital, grid.415719.f
  184. (184) St. James's Hospital, grid.416409.e
  185. (185) Southern General Hospital, grid.413030.5
  186. (186) West Midlands Regional Genetics Service, Birmingham Women's Hospital Healthcare NHS Trust, Edgbaston, Birmingham, UK
  187. (187) Institut Gustave Roussy, grid.14925.3b
  188. (188) Cancer Center of Lyon, grid.462282.8
  189. (189) Centre Georges François Leclerc, grid.418037.9
  190. (190) Centre de Génétique, Centre Hôspitalier Universitaire Dijon, Université de Bourgogne, Dijon, France
  191. (191) Centre Antoine Lacassagne, grid.417812.9
  192. (192) Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents, Hospices Civils de Lyon, Centre Léon Bérard, Lyon, France
  193. (193) Centre Léon Bérard, grid.418116.b
  194. (194) Claude Bernard University Lyon 1, grid.7849.2
  195. (195) Sapienza University of Rome, grid.7841.a
  196. (196) Centro di Riferimento Oncologico, grid.418321.d
  197. (197) Kiel University, grid.9764.c
  198. (198) Leipzig University, grid.9647.c
  199. (199) Heinrich Heine University Düsseldorf, grid.411327.2
  200. (200) Institute of Human Genetics, University Hospital of Schleswig-Holstein, University Kiel, Kiel, Germany
  201. (201) Lund University, grid.4514.4
  202. (202) Umeå University, grid.12650.30
  203. (203) Karolinska University Hospital, grid.24381.3c
  204. (204) Skåne University Hospital, grid.411843.b
  205. (205) NorthShore University HealthSystem, grid.240372.0
  206. (206) Vejle Sygehus, grid.417271.6, Southern Denmark Region
  207. (207) Aarhus University Hospital, grid.154185.c, Central Denmark Region
  208. (208) Department of Clinical Genetics, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
  209. (209) Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
  210. (210) Masaryk Memorial Cancer Institute, grid.419466.8
  211. (211) Royal Brisbane and Women's Hospital, grid.416100.2

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Danish Open Access Indicator

2013: Unused

Research area: Medicine

Danish Bibliometrics Indicator

2013: Level 2

Research area: Medicine

Dimensions Citation Indicators

Times Cited: 392

Field Citation Ratio (FCR): 67.2

Relative Citation ratio (RCR): 13.06

Open Access Info

Green, Accepted