Article open access publication

Genomic evidence for the Pleistocene and recent population history of Native Americans

Science, American Association for the Advancement of Science (AAAS), ISSN 0036-8075

Volume 349, 6250, 2015

DOI:10.1126/science.aab3884, Dimensions: pub.1029259567, PMC: PMC4733658, PMID: 26198033,

Authors

Eriksson, Anders R (11) (12)
Metspalu, Mait (13) (14)
Wall, Jeff (15)
Campos, Paula F (1) (17)
Metspalu, Ene (13) (14)
Karmin, Monika (13) (14)
Warmuth, Vera M (25) (26)
Grimes, Vaughan (34) (35)
Posukh, Olga L (40) (41)
Litvinov, Sergey (13) (47)
Cybulski, Jerome S (53) (54) (55)
Kivisild, Toomas (12) (13)
Villems, Richard (13) (14)
Meltzer, David J (1) (62)
Song, Yun S (3) (4)

Affiliations

Organisations

  1. (1) Natural History Museum of Denmark, grid.507616.3
  2. (2) University of Massachusetts Amherst, grid.266683.f
  3. (3) University of California, Berkeley, grid.47840.3f
  4. (4) University of California System, grid.30389.31
  5. (5) Wellcome Sanger Institute, grid.10306.34
  6. (6) Technical University of Denmark, grid.5170.3, DTU
  7. (7) Pennsylvania State University, grid.29857.31
  8. (8) University of Copenhagen, grid.5254.6, KU
  9. (9) La Trobe University, grid.1018.8
  10. (10) Stanford University, grid.168010.e
  11. (11) King Abdullah University of Science and Technology, grid.45672.32
  12. (12) University of Cambridge, grid.5335.0
  13. (13) Estonian Biocentre, grid.82937.37
  14. (14) University of Tartu, grid.10939.32
  15. (15) University of California, San Francisco, grid.266102.1
  16. (16) Washington State University, grid.30064.31
  17. (17) University of Porto, grid.5808.5
  18. (18) University of Illinois at Urbana Champaign, grid.35403.31
  19. (19) Complutense University of Madrid, grid.4795.f
  20. (20) National Institute of Anthropology and History, grid.462439.e
  21. (21) University of Utah, grid.223827.e
  22. (22) Uppsala University, grid.8993.b
  23. (23) Aarhus University, grid.7048.b, AU
  24. (24) Instituto Politécnico Nacional, grid.418275.d
  25. (25) Evolutionsbiologiskt Centrum, Norbyvägen 18D, 75236 Uppsala, Sweden
  26. (26) University College London, grid.83440.3b
  27. (27) University of Reading, grid.9435.b
  28. (28) School of Geographical Sciences, University Road, Clifton, Bristol BS8 1SS, UK
  29. (29) University of Guadalajara, grid.412890.6
  30. (30) University of Bologna, grid.6292.f
  31. (31) Oregon State University, grid.4391.f
  32. (32) Museum National d'Histoire Naturelle, CNRS, Université Paris 7 Diderot, Sorbonne Paris Cité, Sorbonne Universités, Unité Eco-Anthropologie et Ethnobiologie (UMR7206), Paris, France
  33. (33) University of Zurich, grid.7400.3
  34. (34) Max Planck Institute for Evolutionary Anthropology, grid.419518.0
  35. (35) Memorial University of Newfoundland, grid.25055.37
  36. (36) University of California, Irvine, grid.266093.8
  37. (37) University of Tarapacá, grid.412182.c
  38. (38) Fundação Museu do Homem Americano, grid.472910.9
  39. (39) Federal University of Toulouse Midi-Pyrénées, grid.508721.9
  40. (40) Novosibirsk State University, grid.4605.7
  41. (41) Institute of Cytology and Genetics, grid.418953.2
  42. (42) Siberian Branch of the Russian Academy of Sciences, grid.415877.8
  43. (43) Vavilov Institute of General Genetics, grid.433823.d
  44. (44) Research Centre for Medical Genetics, grid.415876.9
  45. (45) Kemerovo State University, grid.79013.3c
  46. (46) Bashkir State University, grid.77269.3d
  47. (47) Institute of Biochemistry and Genetics of Ufa Scientific Centre, grid.429129.5
  48. (48) Department of Molecular Genetics, Yakut Scientific Centre of Complex Medical Problems, Sergelyahskoe Shosse 4, 677010 Yakutsk, Russia
  49. (49) North-Eastern Federal University, grid.440700.7
  50. (50) Institute of Biological Problems of the North, grid.493323.c
  51. (51) Western Washington University, grid.281386.6
  52. (52) Coast Mountain College, grid.458371.c
  53. (53) Canadian Museum of History, 100 Rue Laurier, Gatineau, Quebec K1A 0M8, Canada
  54. (54) Simon Fraser University, grid.61971.38
  55. (55) Western University, grid.39381.30
  56. (56) Metlakatla Treaty Office, Post Office Box 224, Prince Rupert, BC V8J 3P6, Canada
  57. (57) Sealaska Heritage Institute, grid.438004.b
  58. (58) University of Kansas, grid.266515.3
  59. (59) University of California, Davis, grid.27860.3b
  60. (60) Texas A&M University, grid.264756.4
  61. (61) Santa Barbara Museum of Natural History, grid.421844.f
  62. (62) Southern Methodist University, grid.263864.d

Description

How and when the Americas were populated remains contentious. Using ancient and modern genome-wide data, we found that the ancestors of all present-day Native Americans, including Athabascans and Amerindians, entered the Americas as a single migration wave from Siberia no earlier than 23 thousand years ago (ka) and after no more than an 8000-year isolation period in Beringia. After their arrival to the Americas, ancestral Native Americans diversified into two basal genetic branches around 13 ka, one that is now dispersed across North and South America and the other restricted to North America. Subsequent gene flow resulted in some Native Americans sharing ancestry with present-day East Asians (including Siberians) and, more distantly, Australo-Melanesians. Putative "Paleoamerican" relict populations, including the historical Mexican Pericúes and South American Fuego-Patagonians, are not directly related to modern Australo-Melanesians as suggested by the Paleoamerican Model.

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NORA University Profiles

Technical University of Denmark

University of Copenhagen

Aarhus University

Danish Open Access Indicator

2015: Unused

Research area: Science & Technology

Danish Bibliometrics Indicator

2015: Level 2

Research area: Science & Technology

Dimensions Citation Indicators

Times Cited: 303

Field Citation Ratio (FCR): 117.17

Relative Citation ratio (RCR): 8.18

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