Article open access publication

From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics: meeting report from the third international symposium on “New frontiers in cardiovascular research”

Basic Research in Cardiology, Springer Nature, ISSN 1435-1803

Volume 111, 6, 2016

DOI:10.1007/s00395-016-0586-x, Dimensions: pub.1043602212, PMC: PMC5065587, PMID: 27743118,

Affiliations

Organisations

  1. (1) Monterrey Institute of Technology and Higher Education, grid.419886.a
  2. (2) University of Giessen, grid.8664.c
  3. (3) Kazan Federal University, grid.77268.3c
  4. (4) National Heart Centre Singapore, grid.419385.2
  5. (5) Duke NUS Graduate Medical School, grid.428397.3
  6. (6) Autonomous University of Madrid, grid.5515.4
  7. (7) Klinikum der Universität München, grid.411095.8
  8. (8) Munich Cluster for Systems Neurology, grid.452617.3
  9. (9) University of Hawaii at Manoa, grid.410445.0
  10. (10) Aarhus University Hospital, grid.154185.c, Central Denmark Region
  11. (11) University College London, grid.83440.3b
  12. (12) University of Padua, grid.5608.b
  13. (13) University of Erlangen-Nuremberg, grid.5330.5
  14. (14) Ludwig Maximilian University of Munich, grid.5252.0
  15. (15) Pharmahungary Group, Szeged, Hungary
  16. (16) Semmelweis University, grid.11804.3c
  17. (17) Department of Cardiology, Sarawak Heart Centre, Sarawak, Malaysia
  18. (18) Goethe University Frankfurt, grid.7839.5
  19. (19) Innsbruck Medical University, grid.5361.1
  20. (20) Instituto Nacional de Cardiología, grid.419172.8
  21. (21) UCL Biomedical Research Centre, grid.485385.7
  22. (22) Dong-A University Hospital, grid.412048.b
  23. (23) University of Cape Town, grid.7836.a
  24. (24) University Hospital Aachen, grid.412301.5
  25. (25) King's College London, grid.13097.3c
  26. (26) The James Black Centre, King’s College, University of London, London, UK
  27. (27) Sapporo Medical University, grid.263171.0
  28. (28) Baker IDI Heart and Diabetes Institute, grid.1051.5
  29. (29) Hannover Medical School, grid.10423.34
  30. (30) Bristol Heart Institute, University of Bristol, Bristol Royal Infirmary, Bristol, UK
  31. (31) Institute of Anatomy and Vascular Biology, Westfalian-Wilhelms-University, Münster, Germany

Description

In this meeting report, particularly addressing the topic of protection of the cardiovascular system from ischemia/reperfusion injury, highlights are presented that relate to conditioning strategies of the heart with respect to molecular mechanisms and outcome in patients' cohorts, the influence of co-morbidities and medications, as well as the contribution of innate immune reactions in cardioprotection. Moreover, developmental or systems biology approaches bear great potential in systematically uncovering unexpected components involved in ischemia-reperfusion injury or heart regeneration. Based on the characterization of particular platelet integrins, mitochondrial redox-linked proteins, or lipid-diol compounds in cardiovascular diseases, their targeting by newly developed theranostics and technologies opens new avenues for diagnosis and therapy of myocardial infarction to improve the patients' outcome.

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Aarhus University

Danish Open Access Indicator

2016: Unused

Research area: Medicine

Danish Bibliometrics Indicator

2016: Level 1

Research area: Medicine

Dimensions Citation Indicators

Times Cited: 33

Field Citation Ratio (FCR): 12.4

Relative Citation ratio (RCR): 2.87

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