Article

Synthesis of Oligo-(alkyne-triplet)peptide Constructs.

Organic Letters, American Chemical Society (ACS), ISSN 1523-7052

Volume 19, 24, 2017

DOI:10.1021/acs.orglett.7b03231, Dimensions: pub.1095858164, PMID: 29205042,

Affiliations

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  1. (1) University of Copenhagen, grid.5254.6, KU

Countries

Denmark

Continents

Europe

Description

Copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) click synthesis of an Fmoc-(trispropargyl)amino acid building block for solid phase peptide synthesis (SPPS) of oligo-(trialkyne)peptide constructs is reported. These can carry potentially indefinite numbers of inherent alkyne-triplets, which are click derivatized with GlcNAc-azide into the corresponding glycopeptides.

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NORA University Profiles

University of Copenhagen

Danish Open Access Indicator

2017: Blocked

Research area: Science & Technology

Danish Bibliometrics Indicator

2017: Level 2

Research area: Science & Technology

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Times Cited: 1

Field Citation Ratio (FCR): 0.22

Relative Citation ratio (RCR): 0