Article open access publication

Illness management and recovery: Clinical outcomes of a randomized clinical trial in community mental health centers

PLoS ONE, Public Library of Science (PLoS), ISSN 1932-6203

Volume 13, 4, 2018

DOI:10.1371/journal.pone.0194027, Dimensions: pub.1103170248, PMC: PMC5886399, PMID: 29621284,



  1. (1) Mental Health Services, grid.466916.a, Central Denmark Region
  2. (2) Municipality of Roskilde, Roskilde, Denmark
  3. (3) Copenhagen Trial Unit, Centre for Clinical Intervention Research, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark






OBJECTIVE: Illness Management and Recovery (IMR) is a psychosocial intervention with a recovery-oriented approach. The program has been evaluated in different settings; however evidence for the effects of IMR is still deficient. The aim of this trial was to investigate the benefits and harms of the IMR program compared with treatment as usual in Danish patients with schizophrenia or bipolar disorder. METHOD: The trial was designed as a randomized, assessor-blinded, multi-center, clinical trial investigating the IMR program compared with usual treatment. 198 people diagnosed with schizophrenia or bipolar disorder participated. The primary outcome was the Global Assessment of Functioning (GAF-F) at the end of intervention and the secondary and explorative outcomes included severity of symptoms and service utilization. RESULTS: IMR had no significant effect on functioning, symptoms, substance use or service utilization. CONCLUSION: This randomized trial contributes to the evidence base of IMR by providing a methodological solid base for its conclusions; however the trial has some important limitations. More research is needed to get a firm answer on the effectiveness of the IMR.


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