Article

Effect of Smoking on Periodontitis: A Systematic Review and Meta-regression

American Journal of Preventive Medicine, Elsevier, ISSN 1873-2607

Volume 54, 6, 2018

DOI:10.1016/j.amepre.2018.02.014, Dimensions: pub.1103221173, PMID: 29656920,

Authors

* Corresponding author

Affiliations

Organisations

  1. (1) Aarhus University, grid.7048.b, AU

Countries

Denmark

Continents

Europe

Description

CONTEXT: The study systematically reviewed articles on the association between tobacco smoking and periodontitis, as it has been hypothesized that smoking affects the course of periodontitis through impairment of immunological and vascular mechanisms. EVIDENCE ACQUISITION: Searches of articles indexed in PubMed, Scopus, and Embase were performed up to and including May 2017. Search strategy included MeSH and free terms: periodontitis, periodontal diseases, smoking, tobacco use, tobacco, tobacco products, cigarette, pipe, and cigar. Only original prospective longitudinal studies that investigated the association between smoking and periodontitis incidence or progression were included. Results were shown as combined risk ratio. Meta-regression and subgroup analyses were used to explore potential sources of heterogeneity. Analyses were conducted in August 2017. EVIDENCE SYNTHESIS: Twenty-eight studies were included in the review; of these, only 14 presented data that could be included in the meta-analysis. Pooled adjusted risk ratios estimate that smoking increases the risk of periodontitis by 85% (risk ratio=1.85, 95% CI=1.5, 2.2). Meta-regression demonstrated that age explained 54.2% of the variability between studies, time of follow-up explained 13.5%, loss to follow-up 10.7%, criteria used to assess the periodontal status explained 2.1%, and severity of periodontitis explained 16.9%. CONCLUSIONS: Smoking has a detrimental effect on the incidence and progression of periodontitis. Tobacco smoking, therefore, is important information that should be assessed along with other risk factors for periodontitis.

Research Categories

Main Subject Area

Fields of Research

Sustainable Development Goals

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NORA University Profiles

Aarhus University

Danish Open Access Indicator

2018: Unused

Research area: Medicine

Danish Bibliometrics Indicator

2018: Level 2

Research area: Medicine

Dimensions Citation Indicators

Times Cited: 43

Field Citation Ratio (FCR): 27.05

Relative Citation ratio (RCR): 10.66