
Vaag, Allan
Positions
- , AstraZeneca (Sweden)
- , Steno Diabetes Center
- , National Institute of Child Health and Human Development
- , Novo Nordisk (Denmark)
- , Lund University
- , Rigshospitalet
- , Copenhagen University Hospital
- , University of Copenhagen
- , State Serum Institute
- , Aarhus University
- , Odense University Hospital
- , Astra Zeneca, Göteborg, SE-431 50 Sweden.
- , AstraZenaca, Mölndal, Sweden
- , AstraZeneca Gothenburg, 43150, Mölndal, Sweden
- , AstraZeneca Gothenburg, Mölndal 43150, Sweden
- , Astrazeneca Gothenburg Sweden
- , Center for Fetal Programming, Copenhagen, Denmark
- , Center for Fetal Programming, Orestads Boulevard 5, 2300 Copenhagen S, Denmark
- , Center for Physical Activity Research, Copenhagen University Hospital, Copenhagen, Denmark
- , Centre for Physical Activity Research, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
- , Centre of Inflammation and Metabolism, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
- , Copenhagen University Hospital (Rigshospitalet) Diabetes and Metabolism Denmark
- , Deep Hospital481-Model Town, Ludhiana, Punjab, IndiaDepartment of Clinical SciencesDiabetes and Endocrinology, Clinical Research Centre, Lund University, Malmö, SwedenDepartment of Endocrinology (Diabetes and Metabolism)Rigshospitalet, Copenhagen, Denmark Deep Hospital481-Model Town, Ludhiana, Punjab, IndiaDepartment of Clinical SciencesDiabetes and Endocrinology, Clinical Research Centre, Lund University, Malmö, SwedenDepartment of Endocrinology (Diabetes and Metabolism)Rigshospitalet, Copenhagen, Denmark.
- , Department of Clinical Sciences, Lund University, Skåne University Hospital, SE-205 02 Malmö, Sweden
- , Department of Diabetes and Metabolism, Copenhagen University Hospital, Copenhagen, Denmark
- , Department of Diabetes and Metabolism, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark
- , Department of Endocrinology, Copenhagen University Hospital, Copenhagen, Denmark
- , Department of Endocrinology (Diabetes and Metabolism), Rigshospitalet, University of Copenhagen, Blegdamsvej 9, 2100, Copenhagen, Denmark
- , Department of Endocrinology (Diabetes and Metabolism), Section 7652, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, DK-2100, Copenhagen, Denmark
- , Department of Endocrinology, Diabetes and Metabolism, Copenhagen University Hospital, Copenhagen, Denmark
- , Department of Endocrinology, Diabetes and Metabolism, Rigshospitalet – Section 7652, Tagensvej 20, DK-2200, Copenhagen, Denmark
- , Department of Endocrinology, Diabetes and Metabolism, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
- , Department of Endocrinology, Diabetes and Metabolism, Rigshospitalet, and Copenhagen University, Denmark.
- , Department of Endocrinology (Diabetes and Metabolism) Rigshospitalet Denmark
- , Department of Endocrinology (Diabetes and Metabolism)Rigshospitalet, Copenhagen, Denmark Steno Diabetes CenterGentofte, Denmark.
- , Department of Endocrinology, Diabetes and Metabolism Rigshospitalet Copenhagen University Hospital Copenhagen Denmark
- , Department of Endocrinology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
- , Department of Endocrinology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
- , Department of Endocrinology (S.W.J., A.V.), Rigshospitalet and Copenhagen University, DK-2100 Denmark
- , Department of Endocrinology and.
- , Department of Infectious Diseases, Center for Physical Activity Research, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
- , Department of Infectious Diseases, Centre for Physical Activity Research, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; The Danish Diabetes Academy, Odense University Hospital, Odense, Denmark; Department of Endocrinology (Diabetes and Metabolism), Rigshospitalet, University of Copenhagen, Denmark.
- , Department of Infectious Diseases, Centre of Inflammation and Metabolism, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
- , Department of Medical Endocrinology Copenhagen Denmark
- , Diabetes and Metabolism, Department of Endocrinology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
- , Diabetes and Metabolism, Rigshospitalet Department of Endocrinology Copenhagen Denmark
- , From the Epidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Rockville, MD (WB, MK, and CZ); the Division of Biostatistics and Epidemiology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH (KB); the Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA (DKT and JC); the Centre for Fetal Programming, Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark (SFO); the Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (JC); and the Department of Endocrinology, Rigshospitalet, Copenhagen, Denmark (AV)
- , Rigshospitalet, Department of Endocrinology, University of Copenhagen, Copenhagen, Denmark;
- , Rigshospitalet University Hospital/Copenhagen University Department of Endocrinology, Diabetes and Metabolism Copenhagen Denmark
- , Steno Diabetes Centre A/S, Gentofte, Denmark.
- , b Rigshospitalet , Department of Endocrinology , Copenhagen , Denmark.
- Affiliation
- Publications
- Research
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Affiliation
Publications
selected publications
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academic article
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Maternal glycemic index and glycemic load in pregnancy and offspring metabolic health in childhood and adolescence—a cohort study of 68,471 mother–offspring dyads from the Danish National Birth Cohort.
European Journal of Clinical Nutrition.
73.
2019
Association between genetic risk variants and glucose intolerance during pregnancy in north Indian women.
BMC Medical Genomics.
11.
2018
Danish Centre for Strategic Research in Type 2 Diabetes (DD2) project cohort of newly diagnosed patients with type 2 diabetes: a cohort profile.
BMJ Open.
8.
2018
Escitalopram Ameliorates Hypercortisolemia and Insulin Resistance in Low Birth Weight Men With Limbic Brain Alterations.
The Journal of Clinical Endocrinology & Metabolism.
103.
2018
Gestational Diabetes Mellitus and Renal Function: A Prospective Study With 9- to 16-Year Follow-up After Pregnancy.
Diabetes Care.
41.
2018
Gestational diabetes and maternal obesity are associated with epigenome-wide methylation changes in children.
JCI Insight.
3.
2018
In utero exposure to extra vitamin D from food fortification and the risk of subsequent development of gestational diabetes: the D-tect study.
Nutrition Journal.
17.
2018
Increased expression of microRNA-15a and microRNA-15b in skeletal muscle from adult offspring of women with diabetes in pregnancy..
Human Molecular Genetics.
27.
2018
Plasma ceramide levels are altered in low and normal birth weight men in response to short-term high-fat overfeeding.
Scientific Reports.
8.
2018
Prevalence of micro- and macrovascular diabetes complications at time of type 2 diabetes diagnosis and associated clinical characteristics: A cross-sectional baseline study of 6958 patients in the Danish DD2 cohort.
Journal of Diabetes and its Complications.
32.
2018
Telomere length is reduced in 9- to 16-year-old girls exposed to gestational diabetes in utero.
Diabetologia.
61.
2018
36 h fasting of young men influences adipose tissue DNA methylation of LEP and ADIPOQ in a birth weight-dependent manner.
Clinical Epigenetics.
9.
2017
A retrospective analysis of a societal experiment among the Danish population suggests that exposure to extra doses of vitamin A during fetal development may lower type 2 diabetes mellitus (T2DM) risk later in life.
British Journal Of Nutrition.
117.
2017
Abnormal epigenetic changes during differentiation of human skeletal muscle stem cells from obese subjects.
BMC Medicine.
15.
2017
Adiposity, Dysmetabolic Traits and Earlier Onset of Female Puberty in Adolescent Offspring of Women With Gestational Diabetes Mellitus: A Clinical Study Within the Danish National Birth Cohort.
Diabetes Care.
40.
2017
Childhood body mass index and development of type 2 diabetes throughout adult life—A large‐scale danish cohort study.
Obesity.
25.
2017
Complement factors C4 and C3 are down regulated in response to short term overfeeding in healthy young men.
Scientific Reports.
7.
2017
Complement factors C4 and C3 are down regulated in response to short term overfeeding in healthy young men.
Molecular Immunology.
89.
2017
DNA methylation and gene expression of TXNIP in adult offspring of women with diabetes in pregnancy.
PLoS ONE.
12.
2017
Diagnosing gestational diabetes mellitus in the Danish National Birth Cohort.
Acta Obstetricia Et Gynecologica Scandinavica.
96.
2017
Differential adipokine DNA methylation and gene expression in subcutaneous adipose tissue from adult offspring of women with diabetes in pregnancy.
Clinical Epigenetics.
9.
2017
Dnmt3a is an epigenetic mediator of adipose insulin resistance.
eLife.
6.
2017
Dysregulation of a novel miR-23b/27b-p53 axis impairs muscle stem cell differentiation of humans with type 2 diabetes.
Molecular Metabolism.
6.
2017
Effect of an Intensive Lifestyle Intervention on Glycemic Control in Patients With Type 2 Diabetes: A Randomized Clinical Trial.
JAMA.
318.
2017
Fetal Hyperglycemia Changes Human Preadipocyte Function in Adult Life..
The Journal of Clinical Endocrinology & Metabolism.
102.
2017
Insulin secretion and action in North Indian women during pregnancy.
Diabetic Medicine.
34.
2017
Long-term effect of smartphone-delivered Interval Walking Training on physical activity in patients with type 2 diabetes: protocol for a parallel group single-blinded randomised controlled trial.
BMJ Open.
7.
2017
Maternal protein intake in pregnancy and offspring metabolic health at age 9-16 y: results from a Danish cohort of gestational diabetes mellitus pregnancies and controls..
American Journal of Clinical Nutrition.
106.
2017
Ponderal index at birth associates with later risk of gestational diabetes mellitus.
Archives of Gynecology and Obstetrics.
296.
2017
A Genome-Wide mQTL Analysis in Human Adipose Tissue Identifies Genetic Variants Associated with DNA Methylation, Gene Expression and Metabolic Traits.
PLoS ONE.
11.
2016
A common variation of the PTEN gene is associated with peripheral insulin resistance.
Diabetes & Metabolism.
42.
2016
Adipose tissue transcriptomics and epigenomics in low birthweight men and controls: role of high-fat overfeeding.
Diabetologia.
59.
2016
Are hepatic and soleus lipid content, assessed by magnetic resonance spectroscopy, associated with low birth weight or insulin resistance in a rural Indian population of healthy young men?.
Diabetic Medicine.
33.
2016
Association of parental history of type 2 diabetes with age, lifestyle, anthropometric factors, and clinical severity at type 2 diabetes diagnosis: results from the DD2 study.
Diabetes/Metabolism Research and Reviews.
32.
2016
Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes.
Nature Communications.
7.
2016
Criterion validity and reliability of a smartphone delivered sub-maximal fitness test for people with type 2 diabetes.
BMC Sports Science, Medicine and Rehabilitation.
8.
2016
DNA methylation and gene expression of HIF3A: cross-tissue validation and associations with BMI and insulin resistance.
Clinical Epigenetics.
8.
2016
DNA methylation of loci within ABCG1 and PHOSPHO1 in blood DNA is associated with future type 2 diabetes risk.
Epigenetics.
11.
2016
Disproportionately increased 24-h energy expenditure and fat oxidation in young men with low birth weight during a high-fat overfeeding challenge.
European Journal of Nutrition.
55.
2016
Do very small adipocytes in subcutaneous adipose tissue (a proposed risk factor for insulin insensitivity) have a fetal origin?.
Clinical Nutrition Experimental.
8.
2016
EMPA-REG: Glucose excretion and lipid mobilization – not storage – saves lives.
Journal of Diabetes and its Complications.
30.
2016
Effects of biphasic, basal-bolus or basal insulin analogue treatments on carotid intima-media thickness in patients with type 2 diabetes mellitus: the randomised Copenhagen Insulin and Metformin Therapy (CIMT) trial.
BMJ Open.
6.
2016
Endocrine and metabolic diurnal rhythms in young adult men born small vs appropriate for gestational age.
European Journal of Endocrinology.
175.
2016
Epigenetic programming of adipose-derived stem cells in low birthweight individuals.
Diabetologia.
59.
2016
Gene Expression and DNA Methylation of PPARGC1A in Muscle and Adipose Tissue From Adult Offspring of Women With Diabetes in Pregnancy.
Diabetes.
65.
2016
Genome-wide associations for birth weight and correlations with adult disease.
Nature.
538.
2016
Growth and obesity through the first 7 y of life in association with levels of maternal glycemia during pregnancy: a prospective cohort study..
American Journal of Clinical Nutrition.
103.
2016
Human adipogenesis is associated with genome-wide DNA methylation and gene-expression changes.
Epigenomics.
8.
2016
Impact of the TCF7L2 genotype on risk of hypoglycaemia and glucagon secretion during hypoglycaemia.
Endocrine Connections.
5.
2016
Implementation of interval walking training in patients with type 2 diabetes in Denmark: rationale, design, and baseline characteristics.
Clinical Epidemiology.
Volume 8.
2016
Metabolic and Transcriptional Changes in Cultured Muscle Stem Cells from Low Birth Weight Subjects.
The Journal of Clinical Endocrinology & Metabolism.
101.
2016
Metformin versus placebo in combination with insulin analogues in patients with type 2 diabetes mellitus—the randomised, blinded Copenhagen Insulin and Metformin Therapy (CIMT) trial.
BMJ Open.
6.
2016
Parental smoking during pregnancy and the risk of gestational diabetes in the daughter.
International Journal of Epidemiology.
45.
2016
Plasma acylcarnitine profiling indicates increased fatty acid oxidation relative to tricarboxylic acid cycle capacity in young, healthy low birth weight men.
Physiological Reports.
4.
2016
Plasma amino acid levels are elevated in young, healthy low birth weight men exposed to short‐term high‐fat overfeeding.
Physiological Reports.
4.
2016
Rates of Community-based Antibiotic Prescriptions and Hospital-treated Infections in Individuals With and Without Type 2 Diabetes: A Danish Nationwide Cohort Study, 2004-2012..
Clinical Infectious Diseases.
63.
2016
Smartphone-app-delivered Interval Walking Training In Denmark.
Medicine & Science in Sports & Exercise.
48.
2016
Vitamin D fortification and seasonality of birth in type 1 diabetic cases: D-tect study.
Journal of Developmental Origins of Health and Disease.
7.
2016
Effects of 12 weeks of treatment with fermented milk on blood pressure, glucose metabolism and markers of cardiovascular risk in patients with type 2 diabetes: a randomised double-blind placebo-controlled study.
European Journal of Endocrinology.
172.
2015
Effects of an outdoor bicycle-based intervention in healthy rural Indian men with normal and low birth weight.
Journal of Developmental Origins of Health and Disease.
6.
2015
Erratum to: Metabolic response to 36 hours of fasting in young men born small vs appropriate for gestational age.
Diabetologia.
58.
2015
Gestational and Early Infancy Exposure to Margarine Fortified with Vitamin D through a National Danish Programme and the Risk of Type 1 Diabetes: The D-Tect Study.
PLoS ONE.
10.
2015
Glucose tolerance is associated with differential expression of microRNAs in skeletal muscle: results from studies of twins with and without type 2 diabetes.
Diabetologia.
58.
2015
Glucose-Dependent Insulinotropic Polypeptide Stimulates Osteopontin Expression in the Vasculature via Endothelin-1 and CREB.
Diabetes.
65.
2015
Head-to-head comparison of intensive lifestyle intervention (U-TURN) versus conventional multifactorial care in patients with type 2 diabetes: protocol and rationale for an assessor-blinded, parallel group and randomised trial.
BMJ Open.
5.
2015
Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood.
Human Molecular Genetics.
24.
2015
Impaired cerebral blood flow and oxygenation during exercise in type 2 diabetic patients.
Physiological Reports.
3.
2015
Insulin is not insulin and a unit not a unit.
Diabetes Obesity and Metabolism.
17.
2015
Long-term risk of type 2 diabetes mellitus in relation to BMI and weight change among women with a history of gestational diabetes mellitus: a prospective cohort study.
Diabetologia.
58.
2015
Metabolic response to 36 hours of fasting in young men born small vs appropriate for gestational age.
Diabetologia.
58.
2015
Metformin in combination with various insulin secretagogues in type 2 diabetes and associated risk of cardiovascular morbidity and mortality—A retrospective nationwide study.
Diabetes Research and Clinical Practice.
107.
2015
Microchimerism of male origin in a cohort of Danish girls.
Chimerism.
6.
2015
No evidence of seasonality of birth in adult type 2 diabetes in Denmark.
Diabetologia.
58.
2015
Prescribing practices and clinical predictors of glucose‐lowering therapy within the first year in people with newly diagnosed Type 2 diabetes.
Diabetic Medicine.
32.
2015
Prevalence and risk factors of gestational diabetes in Punjab, North India: results from a population screening program.
European Journal of Endocrinology.
173.
2015
Sulfonylurea in combination with insulin is associated with increased mortality compared with a combination of insulin and metformin in a retrospective Danish nationwide study.
Diabetologia.
58.
2015
Sulphonylurea monotherapy for patients with type 2 diabetes mellitus.
Cochrane Database of Systematic Reviews.
2015
Targeting intensive glycaemic control versus targeting conventional glycaemic control for type 2 diabetes mellitus.
Cochrane Database of Systematic Reviews.
2015
All‐cause mortality and cardiovascular effects associated with the DPP‐IV inhibitor sitagliptin compared with metformin, a retrospective cohort study on the Danish population.
Diabetes Obesity and Metabolism.
16.
2014
Altered DNA Methylation and Differential Expression of Genes Influencing Metabolism and Inflammation in Adipose Tissue From Subjects With Type 2 Diabetes.
Diabetes.
63.
2014
Association of heart failure severity with risk of diabetes: a Danish nationwide cohort study.
Diabetologia.
57.
2014
CTSH regulates β-cell function and disease progression in newly diagnosed type 1 diabetes patients.
Proceedings of the National Academy of Sciences of the United States of America.
111.
2014
Cardiovascular safety of combination therapies with incretin‐based drugs and metformin compared with a combination of metformin and sulphonylurea in type 2 diabetes mellitus – a retrospective nationwide study.
Diabetes Obesity and Metabolism.
16.
2014
Carotid intima-media thickness is reduced 12months after gastric bypass surgery in obese patients with type 2 diabetes or impaired glucose tolerance.
Journal of Diabetes and its Complications.
28.
2014
Genetic versus Non-Genetic Regulation of miR-103, miR-143 and miR-483-3p Expression in Adipose Tissue and Their Metabolic Implications—A Twin Study.
Genes.
5.
2014
Genetic, nongenetic and epigenetic risk determinants in developmental programming of type 2 diabetes.
Acta Obstetricia Et Gynecologica Scandinavica.
93.
2014
Impaired Leptin Gene Expression and Release in Cultured Preadipocytes Isolated From Individuals Born With Low Birth Weight.
Diabetes.
63.
2014
Low Circulating Levels of IGF-1 in Healthy Adults Are Associated With Reduced β-Cell Function, Increased Intramyocellular Lipid, and Enhanced Fat Utilization During Fasting.
The Journal of Clinical Endocrinology & Metabolism.
99.
2014
PPARGC1A DNA methylation in subcutaneous adipose tissue in low birth weight subjects — impact of 5days of high-fat overfeeding.
Metabolism.
63.
2014
Physical Activity and Sedentary Behaviors Associated With Risk of Progression From Gestational Diabetes Mellitus to Type 2 Diabetes Mellitus: A Prospective Cohort Study.
JAMA Internal Medicine.
174.
2014
Physical inactivity affects skeletal muscle insulin signaling in a birth weight-dependent manner.
Journal of Diabetes and its Complications.
28.
2014
Prepregnancy low-carbohydrate dietary pattern and risk of gestational diabetes mellitus: a prospective cohort study.
American Journal of Clinical Nutrition.
99.
2014
Pre‐natal undernutrition and post‐natal overnutrition are associated with permanent changes in hepatic metabolism markers and fatty acid composition in sheep.
Acta Physiologica.
210.
2014
Rationale, design, and method of the Diabetes & Women's Health study – a study of long‐term health implications of glucose intolerance in pregnancy and their determinants.
Acta Obstetricia Et Gynecologica Scandinavica.
93.
2014
Subclinical inflammation during third trimester of pregnancy was not associated with markers of the metabolic syndrome in young adult offspring.
Obesity.
22.
2014
Sulfonylurea versus metformin monotherapy in patients with type 2 diabetes: a Cochrane systematic review and meta-analysis of randomized clinical trials and trial sequential analysis.
CMAJ Open.
2.
2014
Targeting intensive versus conventional glycaemic control for type 1 diabetes mellitus: a systematic review with meta-analyses and trial sequential analyses of randomised clinical trials.
BMJ Open.
4.
2014
Young men with low birthweight exhibit decreased plasticity of genome-wide muscle DNA methylation by high-fat overfeeding.
Diabetologia.
57.
2014
-
dataset
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Additional file 2: of Association between genetic risk variants and glucose intolerance during pregnancy in north Indian women.
springer-nature.
2018
Baseline clinical characteristics in adult offspring of women with gestational diabetes (O-GDM) or type 1 diabetes (O-T1DM) compared to offspring of women from the background population (O-BP)..
public-library-of-science.
2017
Correlations between TXNIP DNA methylation and gene expression and offspring markers of metabolic disease..
public-library-of-science.
2017
TXNIP DNA methylation and gene expression in subcutaneous adipose tissue, skeletal muscle and blood from offspring of women with gestational diabetes (O-GDM) or type 1 diabetes (O-T1DM) compared to offspring of women from the background population (O-BP) in univariate and multivariate analyses..
public-library-of-science.
2017
TXNIP DNA methylation and gene expression in subjects with normal glucose tolerance compared to subjects with prediabetes..
public-library-of-science.
2017
A Genome-Wide mQTL Analysis in Human Adipose Tissue Identifies Genetic Variants Associated with DNA Methylation, Gene Expression and Metabolic Traits.
public-library-of-science.
2016
Characteristics of 119 Scandinavian men included in the mQTL analysis..
public-library-of-science.
2016
Identified cis-mQTLs where DNA methylation potentially mediates the interactions between a genotype and a phenotype in human adipose tissue..
public-library-of-science.
2016
Number of significant eQTL results in human adipose tissue..
public-library-of-science.
2016
Number of significant mQTL results in human adipose tissue..
public-library-of-science.
2016
Gestational and Early Infancy Exposure to Margarine Fortified with Vitamin D through a National Danish Programme and the Risk of Type 1 Diabetes: The D-Tect Study.
public-library-of-science.
2015
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hide from search
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Characteristics for the total cohort, triglyceride and total cholesterol groups..
public-library-of-science.
2020
Cumulative incidences of toxicity..
public-library-of-science.
2020
Dyslipidemia at diagnosis of childhood acute lymphoblastic leukemia.
public-library-of-science.
2020
Epigenome- and Transcriptome-wide Changes in Muscle Stem Cells from Low Birth Weight Men.
taylor-&-francis-group.
2020
Anthropometry at birth, infancy and adolescence of subjects born appropriate for gestational age (AGA) and small for gestational age (SGA)..
public-library-of-science.
2013
Association between CES1 mRNA expression level in adipose tissue and measures of glucose and lipid metabolism..
public-library-of-science.
2013
Association of CES1 gene copy number with measures of adiposity and metabolic regulation..
public-library-of-science.
2013
Baseline Characteristics.
public-library-of-science.
2013
Clinical characteristics of the FDR group (n = 124) stratified according to glucose tolerance status..
public-library-of-science.
2013
Dietary Glycemic Index during Pregnancy Is Associated with Biomarkers of the Metabolic Syndrome in Offspring at Age 20 Years.
public-library-of-science.
2013
Effect of selected variables on CES1 mRNA expression level in adipose tissue..
public-library-of-science.
2013
Effects of early infant weight gain (ΔSDSbirth to 3 months) on glucose metabolism, body composition, and cardiovascular risk factors at adolescence..
public-library-of-science.
2013
Expression and phosphorylation of key proteins involved in MAPK-signalling..
public-library-of-science.
2013
Heritability of CES1 and CES1P1 mRNA expression levels in adipose tissue..
public-library-of-science.
2013
Pre- and Early-Postnatal Nutrition Modify Gene and Protein Expressions of Muscle Energy Metabolism Markers and Phospholipid Fatty Acid Composition in a Muscle Type Specific Manner in Sheep.
public-library-of-science.
2013
References and efficiencies of the primer sequences that were used for qPCR..
public-library-of-science.
2013
Total triglyceride (TG) and ceramide (Cer) contents in muscles of 6-months old lambs..
public-library-of-science.
2013
Akt2 influences glycogen synthase activity in human skeletal muscle through regulation of NH2-terminal (sites 2 + 2a) phosphorylation.
AJP Endocrinology and Metabolism.
2013
Carboxylesterase 1 Gene Duplication and mRNA Expression in Adipose Tissue Are Linked to Obesity and Metabolic Function.
PLoS ONE.
2013
DPP-4 inhibitors and GLP-1 agonists in type 2 diabetes - early assessment of cardiovascular safety in a nationwide setting.
European Heart Journal.
2013
Dietary Glycemic Index during Pregnancy Is Associated with Biomarkers of the Metabolic Syndrome in Offspring at Age 20 Years.
PLoS ONE.
2013
Differences in mortality and cardiovascular risk associated with insulin in combination with individual insulin secretagogues or metformin - a nationwide study.
European Heart Journal.
2013
Does physical activity during pregnancy adversely influence markers of the metabolic syndrome in adult offspring? A prospective study over two decades.
Journal of Epidemiology & Community Health.
2013
Effect of birth weight and 12 weeks of exercise training on exercise-induced AMPK signaling in human skeletal muscle.
AJP Endocrinology and Metabolism.
2013
Increased nocturnal fat oxidation in young healthy men with low birth weight: Results from 24-h whole-body respiratory chamber measurements.
Metabolism.
2013
Insulin resistance and impaired pancreatic β-cell function in adult offspring of women with diabetes in pregnancy..
The Journal of Clinical Endocrinology & Metabolism.
2013
New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism.
Nature Genetics.
2013
Pre- and Early-Postnatal Nutrition Modify Gene and Protein Expressions of Muscle Energy Metabolism Markers and Phospholipid Fatty Acid Composition in a Muscle Type Specific Manner in Sheep.
PLoS ONE.
2013
Sulphonylurea monotherapy for patients with type 2 diabetes mellitus
2013
The influence of early exposure to vitamin D for development of diseases later in life.
BMC Public Health.
2013
Treating allergic rhinitis with depot-steroid injections increase risk of osteoporosis and diabetes.
Respiratory Medicine.
2013
Characteristics of monozygotic twins discordant for type 2 diabetes..
public-library-of-science.
2012
Differentially methylated genes..
public-library-of-science.
2012
Differentially methylated type 2 diabetes susceptibility genes..
public-library-of-science.
2012
Genome-Wide Analysis of DNA Methylation Differences in Muscle and Fat from Monozygotic Twins Discordant for Type 2 Diabetes.
public-library-of-science.
2012
Genotype and allele frequency of rs738409 among individuals with traits related to the metabolic syndrome in Inter99..
public-library-of-science.
2012
Quantitative traits among individuals from the Inter99 cohort according to PNPLA3 rs738409 genotype..
public-library-of-science.
2012
The PNPLA3 rs738409 G-Allele Associates with Reduced Fasting Serum Triglyceride and Serum Cholesterol in Danes with Impaired Glucose Regulation.
public-library-of-science.
2012
Associations between rs900400 near LEKR1 and CCNL1 and birth weight, birth length and ponderal index in the Danish Inter99 sample..
public-library-of-science.
2011
Associations between rs900400 near LEKR1 and CCNL1 and quantitative metabolic traits during an oral glucose tolerance test in 5,484 non-diabetic participants of the Inter99 study and 6,915 non-diabetic men from the METSIM study..
public-library-of-science.
2011
Birth weight characteristics of participants from the Inter99 study and characteristics of non-diabetic participants from the Inter99 study and from the METSIM study..
public-library-of-science.
2011
Meta-analyses of rs900400 and insulin traits including up to 12,394 individuals from the Inter99 and the METSIM study..
public-library-of-science.
2011
Table S1 - The Birth Weight Lowering C-Allele of rs900400 Near LEKR1 and CCNL1 Associates with Elevated Insulin Release following an Oral Glucose Challenge.
public-library-of-science.
2011
Analyses of obesity risk scores and adult BMI, birth weight and ponderal index in a subsample of Inter99 with available genotype and birth weight data (n = 2,926)..
public-library-of-science.
2010
Do Gene Variants Influencing Adult Adiposity Affect Birth Weight? A Population-Based Study of 24 Loci in 4,744 Danish Individuals.
public-library-of-science.
2010
Clinical characteristics of participants..
public-library-of-science.
2009
Clinical characteristics of subjects..
public-library-of-science.
2009
Gene Expression in Skeletal Muscle Biopsies from People with Type 2 Diabetes and Relatives: Differential Regulation of Insulin Signaling Pathways.
public-library-of-science.
2009
Genes differentially expressed in first degree relatives of people with type 2 diabetes..
public-library-of-science.
2009
Genes differentially expressed in people with type 2 diabetes..
public-library-of-science.
2009
Genetic Variation in ATP5O Is Associated with Skeletal Muscle ATP50 mRNA Expression and Glucose Uptake in Young Twins.
public-library-of-science.
2009
Heritability of ATP5O mRNA expression in skeletal muscle from 86 young and 69 elderly twins during clamp..
public-library-of-science.
2009
Pathways/functions regulated on gene level..
public-library-of-science.
2009
Effect of Adjunct Metformin Treatment in Patients with Type-1 Diabetes and Persistent Inadequate Glycaemic Control. A Randomized Study.
public-library-of-science.
2008
Effect of metformin versus placebo on follow-up (intermediate and study visit) levels of HbA1c and insulin doses in 72 patients with type-1 diabetes during a one year period..
public-library-of-science.
2008
Inclusion, exclusion and withdrawal criteria.
public-library-of-science.
2008
Metabolism-related variables in 100 patients with type-1 diabetes before and after one year of treatment with metformin or placebo..
public-library-of-science.
2008
Non-hypoglycaemia-related serious adverse events in 100 patients with type-1 diabetes allocated treatment with metformin or placebo for one year..
public-library-of-science.
2008
Reported hypoglycaemic episodes in patients with type-1 diabetes during one year of treatment with metformin or placebo..
public-library-of-science.
2008
Subject characteristics at enrolment (−1 month) for 100 patients with type-1 diabetes..
public-library-of-science.
2008
TXNIP Regulates Peripheral Glucose Metabolism in Humans.
public-library-of-science.
2007
Research
principal investigator on
- Dynamics of Stem Cell Epigenetics in Response to Lifestyle Changes awarded by Novo Nordisk Foundation 2016 - 2017
- Danish title: VICYDIP - The role of epigenetics in the evil cycle of diabetes and pregnancy awarded by Danish Ministry of Higher Education and Science 2014 - 2016
- Subcutaneous adipose tissue expandability and ex vivo preadipocyte functions in low birth weight individuals - impact of a 6 weeks carbohydrate overfeeding challenge awarded by Novo Nordisk Foundation 2013 - 2014
Contact
full name
- Allan Vaag
- Allan Arthur Vaag