selected publications
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academic article
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Abnormal islet sphingolipid metabolism in type 1 diabetes.
Diabetologia.
61.
2018
Cell Type-Selective Expression of Circular RNAs in Human Pancreatic Islets.
Non-Coding RNA.
4.
2018
Hepatitis B virus suppresses the secretion of insulin-like growth factor binding protein 1 to facilitate anti-apoptotic IGF-1 effects in HepG2 cells.
Experimental Cell Research.
370.
2018
Hepatitis B virus upregulates host microRNAs that target apoptosis-regulatory genes in an in vitro cell model.
Experimental Cell Research.
371.
2018
Influence of Disease Duration on Circulating Levels of miRNAs in Children and Adolescents with New Onset Type 1 Diabetes.
Non-Coding RNA.
4.
2018
MicroRNAs and histone deacetylase inhibition-mediated protection against inflammatory β-cell damage.
PLoS ONE.
13.
2018
Plasma lipid species at type 1 diabetes onset predict residual beta-cell function after 6 months.
Metabolomics.
14.
2018
The emerging role of lncRNAs in inflammatory bowel disease.
Experimental & Molecular Medicine.
50.
2018
miRNAs regulate development and function of regulatory T-cells in recent onset islet autoimmunity in pre-Type 1 diabetes.
Non-coding RNA Investigation.
2.
2018
‘25‐Hydroxyvitamin D, Autoantigenic and Total Antibody Concentrations: Results from a Danish Case–control Study of Newly Diagnosed Patients with Childhood Type 1 Diabetes and their Healthy Siblings’.
Scandinavian Journal of Immunology.
87.
2018
25-Hydroxyvitamin D and Peripheral Immune Mediators: Results from Two Nationwide Danish Pediatric Cohorts.
Nutrients.
9.
2017
Circulating microRNA levels predict residual beta cell function and glycaemic control in children with type 1 diabetes mellitus.
Diabetologia.
60.
2017
High Neonatal Blood Iron Content Is Associated with the Risk of Childhood Type 1 Diabetes Mellitus.
Nutrients.
9.
2017
Increased mortality in a Danish cohort of young people with Type 1 diabetes mellitus followed for 24 years.
Diabetic Medicine.
34.
2017
Levels of soluble TREM‐1 in children with newly diagnosed type 1 diabetes and their siblings without type 1 diabetes: a Danish case–control study.
Pediatric Diabetes.
18.
2017
Long non-coding RNAs as novel players in β cell function and type 1 diabetes.
Human Genomics.
11.
2017
Low perinatal zinc status is not associated with the risk of type 1 diabetes in children.
Pediatric Diabetes.
18.
2017
Neonatal levels of adiponectin, interleukin-10 and interleukin-12 are associated with the risk of developing type 1 diabetes in childhood and adolescence: A nationwide Danish case-control study.
Clinical Immunology.
174.
2017
Pannexin-2-deficiency sensitizes pancreatic β-cells to cytokine-induced apoptosis in vitro and impairs glucose tolerance in vivo.
Molecular and Cellular Endocrinology.
448.
2017
Survey of 800+ data sets from human tissue and body fluid reveals xenomiRs are likely artifacts.
RNA.
23.
2017
The identification and functional annotation of RNA structures conserved in vertebrates.
Genome Research.
27.
2017
Type 1 Diabetes Candidate Genes Linked to Pancreatic Islet Cell Inflammation and Beta-Cell Apoptosis.
Genes.
8.
2017
Type 1 diabetes genome-wide association studies: not to be lost in translation.
Clinical & Translational Immunology.
6.
2017
A Systematic Comparison of Purification and Normalization Protocols for Quantitative MicroRNA Expressional Profiling in Insulin-Producing Cells.
International Journal of Molecular Sciences.
17.
2016
A20 Inhibits β-Cell Apoptosis by Multiple Mechanisms and Predicts Residual β-Cell Function in Type 1 Diabetes.
Endocrinology.
30.
2016
Effects of the genome on immune regulation in type 1 diabetes.
Pediatric Diabetes.
17.
2016
GLP-1 Induces Barrier Protective Expression in Brunner's Glands and Regulates Colonic Inflammation.
Inflammatory Bowel Diseases.
22.
2016
Genetic Risk Score Modelling for Disease Progression in New-Onset Type 1 Diabetes Patients: Increased Genetic Load of Islet-Expressed and Cytokine-Regulated Candidate Genes Predicts Poorer Glycemic Control.
Journal of Diabetes Research.
2016.
2016
Genetic risk factors for type 1 diabetes.
The Lancet.
387.
2016
Identification of valid reference genes for microRNA expression studies in a hepatitis B virus replicating liver cell line.
BMC Research Notes.
9.
2016
Lipidomic and metabolomic characterization of a genetically modified mouse model of the early stages of human type 1 diabetes pathogenesis.
Metabolomics.
12.
2016
Metabolomic Biomarkers in the Progression to Type 1 Diabetes.
Current Diabetes Reports.
16.
2016
MicroRNAs as regulators of beta‐cell function and dysfunction.
Diabetes/Metabolism Research and Reviews.
32.
2016
Neonatal vitamin D status is not associated with later risk of type 1 diabetes: results from two large Danish population-based studies.
Diabetologia.
59.
2016
No Contribution of GAD-65 and IA-2 Autoantibodies around Time of Diagnosis to the Increasing Incidence of Juvenile Type 1 Diabetes: A 9-Year Nationwide Danish Study.
International Journal of Endocrinology.
2016.
2016
Potential beneficial effects of a gluten-free diet in newly diagnosed children with type 1 diabetes: a pilot study.
SpringerPlus.
5.
2016
Systematic Evaluation of Genes and Genetic Variants Associated with Type 1 Diabetes Susceptibility.
The Journal of Immunology.
196.
2016
The genetic and regulatory architecture of ERBB3-type 1 diabetes susceptibility locus.
Molecular and Cellular Endocrinology.
419.
2016
Alu Elements as Novel Regulators of Gene Expression in Type 1 Diabetes Susceptibility Genes?.
Genes.
6.
2015
Genes Affecting β-Cell Function in Type 1 Diabetes.
Current Diabetes Reports.
15.
2015
Genetic Determinants of Enterovirus Infections: Polymorphisms in Type 1 Diabetes and Innate Immune Genes in the MIDIA Study.
Viral Immunology.
28.
2015
Levels of adiponectin and leptin at onset of type 1 diabetes have changed over time in children and adolescents.
Acta Diabetologica.
52.
2015
Novel Association Between Immune-Mediated Susceptibility Loci and Persistent Autoantibody Positivity in Type 1 Diabetes.
Diabetes.
64.
2015
Polymorphisms in the CTSH gene may influence the progression of diabetic retinopathy: a candidate-gene study in the Danish Cohort of Pediatric Diabetes 1987 (DCPD1987).
Graefe's Archive for Clinical and Experimental Ophthalmology.
253.
2015
Residual β-cell function and the insulin-like growth factor system in Danish children and adolescents with type 1 diabetes..
The Journal of Clinical Endocrinology & Metabolism.
100.
2015
Shared Genetic Basis for Type 1 Diabetes, Islet Autoantibodies, and Autoantibodies Associated With Other Immune-Mediated Diseases in Families With Type 1 Diabetes.
Diabetes Care.
38.
2015
TYK2, a Candidate Gene for Type 1 Diabetes, Modulates Apoptosis and the Innate Immune Response in Human Pancreatic β-Cells.
Diabetes.
64.
2015
Transcriptomic landscape of lncRNAs in inflammatory bowel disease.
Genome Medicine.
7.
2015
Bifurcation analysis of an existing mathematical model reveals novel treatment strategies and suggests potential cure for type 1 diabetes..
Mathematical Medicine and Biology A Journal of the IMA.
31.
2014
CTSH regulates β-cell function and disease progression in newly diagnosed type 1 diabetes patients.
Proceedings of the National Academy of Sciences of the United States of America.
111.
2014
Circulating MicroRNAs in Plasma of Hepatitis B e Antigen Positive Children Reveal Liver-Specific Target Genes.
International Journal of Hepatology.
2014.
2014
Differences in MBL levels between juvenile patients newly diagnosed with type 1 diabetes and their healthy siblings.
Molecular Immunology.
62.
2014
Effects of GWAS-Associated Genetic Variants on lncRNAs within IBD and T1D Candidate Loci.
PLoS ONE.
9.
2014
Genetic versus Non-Genetic Regulation of miR-103, miR-143 and miR-483-3p Expression in Adipose Tissue and Their Metabolic Implications—A Twin Study.
Genes.
5.
2014
Genetics of diabetes – Are we missing the genes or the disease?.
Molecular and Cellular Endocrinology.
382.
2014
No association between type 1 diabetes and genetic variation in vitamin D metabolism genes: a Danish study.
Pediatric Diabetes.
15.
2014
Spatially conserved regulatory elements identified within human and mouse Cd247 gene using high-throughput sequencing data from the ENCODE project.
Gene.
545.
2014
Systemic Levels of CCL2, CCL3, CCL4 and CXCL8 Differ According to Age, Time Period and Season among Children Newly Diagnosed with type 1 Diabetes and their Healthy Siblings.
Scandinavian Journal of Immunology.
80.
2014
Temporal profiling of cytokine-induced genes in pancreatic β-cells by meta-analysis and network inference.
Genomics.
103.
2014
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dataset
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Data_Sheet_1_Breast Milk-Derived Extracellular Vesicles Enriched in Exosomes From Mothers With Type 1 Diabetes Contain Aberrant Levels of microRNAs.docx.
frontiers.
2019
Data_Sheet_2_Breast Milk-Derived Extracellular Vesicles Enriched in Exosomes From Mothers With Type 1 Diabetes Contain Aberrant Levels of microRNAs.xlsx.
frontiers.
2019
Blood plasma lipidomics peak area data from 123 pediatric patients diagnosed with type 1 diabetes mellitus generated by targeted mass spectrometry.
springer-nature.
2018
MicroRNAs and histone deacetylase inhibition-mediated protection against inflammatory β-cell damage.
public-library-of-science.
2018
Summary of miR microarray results..
public-library-of-science.
2018
miRs regulated by cytokines and Givinostat..
public-library-of-science.
2018
Common structure-disruptive SNPs within IBD and T1D loci-associated lncRNAs..
public-library-of-science.
2014
Effects of GWAS-Associated Genetic Variants on lncRNAs within IBD and T1D Candidate Loci.
public-library-of-science.
2014
IBD and T1D candidate gene associated lncRNAs..
public-library-of-science.
2014
Structure-disruptive SNPs and their-associated lncRNAs..
public-library-of-science.
2014
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hide from search
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Characteristics of children with chronic hepatitis B and of healthy controls..
public-library-of-science.
2013
Clinical and demographic data at onset and 1 month (‡) after diagnosis by age groups: *P<0.05..
public-library-of-science.
2013
Differential Plasma MicroRNA Profiles in HBeAg Positive and HBeAg Negative Children with Chronic Hepatitis B.
public-library-of-science.
2013
Expressional profiling of thirty candidate genes divided into four interaction networks (A–D) demonstrating genetic and protein interactions..
public-library-of-science.
2013
Gene set enrichment analysis..
public-library-of-science.
2013
Genes in consensus network of the DR3/DR3 and DR3/DRX groups..
public-library-of-science.
2013
Genes in consensus networks of the DR3/DR4, DR4/DR4 and DR4/DRX groups..
public-library-of-science.
2013
Plasma levels of circulating miRNAs in children with CHB relative to healthy controls..
public-library-of-science.
2013
Stimulated C-peptide (pmol/L), HbA1c (%) and IDAA1c during 12 months follow up..
public-library-of-science.
2013
Summarization of the genes occurring most frequently in the network modules for each HLA risk group..
public-library-of-science.
2013
Table S1 - Hepatitis B Surface Antigen Quantity Positively Correlates with Plasma Levels of microRNAs Differentially Expressed in Immunological Phases of Chronic Hepatitis B in Children.
public-library-of-science.
2013
The enrichment of the four interaction networks for significant SNPs associated with T1D in the WTCCC study is measured..
public-library-of-science.
2013
The top significant networks modules identified for each HLA risk group..
public-library-of-science.
2013
Complex Multi-Block Analysis Identifies New Immunologic and Genetic Disease Progression Patterns Associated with the Residual β-Cell Function 1 Year after Diagnosis of Type 1 Diabetes.
PLoS ONE.
2013
Differential Plasma MicroRNA Profiles in HBeAg Positive and HBeAg Negative Children with Chronic Hepatitis B.
PLoS ONE.
2013
Hepatitis B Surface Antigen Quantity Positively Correlates with Plasma Levels of microRNAs Differentially Expressed in Immunological Phases of Chronic Hepatitis B in Children.
PLoS ONE.
2013
Residual β-Cell Function 3–6 Years After Onset of Type 1 Diabetes Reduces Risk of Severe Hypoglycemia in Children and Adolescents.
Diabetes Care.
2013
Selenium supplementation for patients with Graves’ hyperthyroidism (the GRASS trial): study protocol for a randomized controlled trial.
Trials.
2013
Association to the chromosome 5p13 region in Danish multiplex/simplex families, BDD cohort and the Swedish case-control material..
public-library-of-science.
2012
Association to the chromosome 5p13 region in Swedish multiplex/simplex families..
public-library-of-science.
2012
Haplotype association; Swedish – and Danish families..
public-library-of-science.
2012
T1D data materials..
public-library-of-science.
2012
Table S1 - HTR1A a Novel Type 1 Diabetes Susceptibility Gene on Chromosome 5p13-q13.
public-library-of-science.
2012