selected publications
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academic article
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Biopolymer nanogels improve antibacterial activity and safety profile of a novel lysine-based α-peptide/β-peptoid peptidomimetic.
European Journal of Pharmaceutics and Biopharmaceutics.
128.
2018
Ciprofloxacin-loaded sodium alginate/poly (lactic-co-glycolic acid) electrospun fibrous mats for wound healing.
European Journal of Pharmaceutics and Biopharmaceutics.
123.
2018
Combining diagnostic methods for antimicrobial susceptibility testing – A comparative approach.
Journal of Microbiological Methods.
144.
2018
Evaluation of drug permeation under fed state conditions using mucus-covered Caco-2 cell epithelium.
European Journal of Pharmaceutical Sciences.
118.
2018
Fluorophore labeling of a cell-penetrating peptide significantly alters the mode and degree of biomembrane interaction.
Scientific Reports.
8.
2018
Immunogenicity investigations of lipidoid structures in vitro and in silico: Modulating lipidoid-mediated TLR4 activation by nanoparticle design.
Molecular Therapy - Nucleic Acids.
11.
2018
In Vitro ADME Properties of Two Novel Antimicrobial Peptoid-Based Compounds as Potential Agents against Canine Pyoderma.
Molecules.
23.
2018
Poly(ethylene carbonate)‐containing polylactic acid microparticles with rifampicin improve drug delivery to macrophages.
Journal of Pharmacy and Pharmacology.
70.
2018
Stereochemistry as a determining factor for the effect of a cell-penetrating peptide on cellular viability and epithelial integrity..
Biochemical Journal.
475.
2018
The role of mucus as an invisible cloak to transepithelial drug delivery by nanoparticles.
Advanced Drug Delivery Reviews.
124.
2018
Animal models for evaluation of oral delivery of biopharmaceuticals.
Journal of Controlled Release.
268.
2017
Engineering of small interfering RNA-loaded lipidoid-poly(DL-lactic-co-glycolic acid) hybrid nanoparticles for highly efficient and safe gene silencing: A quality by design-based approach.
European Journal of Pharmaceutics and Biopharmaceutics.
120.
2017
Fluorophore labeling of a cell-penetrating peptide induces differential effects on its cellular distribution and affects cell viability.
Biochimica et Biophysica Acta (BBA) - Biomembranes.
1859.
2017
Innovative Methods and Applications in Mucoadhesion Research.
Macromolecular Bioscience.
17.
2017
Lysine‐Based α‐Peptide/β‐Peptoid Peptidomimetics: Influence of Hydrophobicity, Fluorination, and Distribution of Cationic Charge on Antimicrobial Activity and Cytotoxicity.
ChemMedChem.
12.
2017
The impact of particle preparation methods and polymorphic stability of lipid excipients on protein distribution in microparticles.
Drug Development and Industrial Pharmacy.
43.
2017
Antimicrobial activity of GN peptides and their mode of action.
Biopolymers.
106.
2016
Cell-penetrating peptides as tools to enhance non-injectable delivery of biopharmaceuticals.
Tissue Barriers.
4.
2016
Cell‐Penetrating Peptides as Carriers for Oral Delivery of Biopharmaceuticals.
Basic & Clinical Pharmacology & Toxicology.
118.
2016
Delivery of siRNA Complexed with Palmitoylated α-Peptide/β-Peptoid Cell-Penetrating Peptidomimetics: Membrane Interaction and Structural Characterization of a Lipid-Based Nanocarrier System..
Molecular Pharmaceutics.
13.
2016
Impact of Lipid-Based Drug Delivery Systems on the Transport and Uptake of Insulin Across Caco-2 Cell Monolayers.
Journal of Pharmaceutical Sciences.
105.
2016
Interactions between Surfactants in Solution and Electrospun Protein Fibers: Effects on Release Behavior and Fiber Properties..
Molecular Pharmaceutics.
13.
2016
Large-Scale Biophysical Evaluation of Protein PEGylation Effects: In Vitro Properties of 61 Protein Entities..
Molecular Pharmaceutics.
13.
2016
Quantification of pharmaceutical peptides in human plasma by LC-ICP-MS sulfur detection.
Journal of Analytical Atomic Spectrometry.
31.
2016
Soft hydrogels interpenetrating silicone—A polymer network for drug‐releasing medical devices.
Journal of Biomedical Materials Research Part B Applied Biomaterials.
104.
2016
Bioactive protein-based nanofibers interact with intestinal biological components resulting in transepithelial permeation of a therapeutic protein.
International Journal of Pharmaceutics.
495.
2015
Cell-Penetrating Antimicrobial Peptides – Prospectives for Targeting Intracellular Infections.
Pharmaceutical Research.
32.
2015
Characterization of particulate drug delivery systems for oral delivery of Peptide and protein drugs..
Current Pharmaceutical Design.
21.
2015
Conjugation of cell-penetrating peptides to parathyroid hormone affects its structure, potency, and transepithelial permeation..
Bioconjugate Chemistry.
26.
2015
End group modification: Efficient tool for improving activity of antimicrobial peptide analogues towards Gram-positive bacteria.
European Journal of Pharmaceutics and Biopharmaceutics.
95.
2015
Hyaluronic Acid-Based Nanogels Produced by Microfluidics-Facilitated Self-Assembly Improves the Safety Profile of the Cationic Host Defense Peptide Novicidin.
Pharmaceutical Research.
32.
2015
Improved insulin loading in poly(lactic-co-glycolic) acid (PLGA) nanoparticles upon self-assembly with lipids.
International Journal of Pharmaceutics.
482.
2015
Investigation of protein distribution in solid lipid particles and its impact on protein release using coherent anti-Stokes Raman scattering microscopy.
Journal of Controlled Release.
197.
2015
Investigation of skin permeation, ex vivo inhibition of venom-induced tissue destruction, and wound healing of African plants used against snakebites.
Journal of Ethnopharmacology.
165.
2015
Mechanistic profiling of the siRNA delivery dynamics of lipid–polymer hybrid nanoparticles.
Journal of Controlled Release.
201.
2015
Mucus as a Barrier to Drug Delivery – Understanding and Mimicking the Barrier Properties.
Basic & Clinical Pharmacology & Toxicology.
116.
2015
Nanoparticle-mediated delivery of the antimicrobial peptide plectasin against Staphylococcus aureus in infected epithelial cells.
European Journal of Pharmaceutics and Biopharmaceutics.
92.
2015
Penetratin-Mediated Transepithelial Insulin Permeation: Importance of Cationic Residues and pH for Complexation and Permeation.
The AAPS Journal.
17.
2015
Selenium as an alternative peptide label – comparison to fluorophore-labelled penetratin.
European Journal of Pharmaceutical Sciences.
67.
2015
Steric and interactive barrier properties of intestinal mucus elucidated by particle diffusion and peptide permeation.
European Journal of Pharmaceutics and Biopharmaceutics.
95.
2015
Surface coating of siRNA–peptidomimetic nano-self-assemblies with anionic lipid bilayers: enhanced gene silencing and reduced adverse effects in vitro.
Nanoscale.
7.
2015
Sustained prevention of biofilm formation on a novel silicone matrix suitable for medical devices.
European Journal of Pharmaceutics and Biopharmaceutics.
94.
2015
Three‐Dimensional Printing of Drug‐Eluting Implants: Preparation of an Antimicrobial Polylactide Feedstock Material.
Journal of Pharmaceutical Sciences.
104.
2015
Property profiling of biosimilar mucus in a novel mucus-containing in vitro model for assessment of intestinal drug absorption.
European Journal of Pharmaceutics and Biopharmaceutics.
87.
2014
Self-nanoemulsifying drug delivery systems for oral insulin delivery: In vitro and in vivo evaluations of enteric coating and drug loading.
International Journal of Pharmaceutics.
477.
2014
Solid Lipid Particles for Oral Delivery of Peptide and Protein Drugs II – The Digestion of Trilaurin Protects Desmopressin from Proteolytic Degradation.
Pharmaceutical Research.
31.
2014
Solid Lipid Particles for Oral Delivery of Peptide and Protein Drugs III — the Effect of Fed State Conditions on the In Vitro Release and Degradation of Desmopressin.
The AAPS Journal.
16.
2014
Tailoring cytotoxicity of antimicrobial peptidomimetics with high activity against multidrug-resistant Escherichia coli..
Journal of Medicinal Chemistry.
57.
2014
The surface charge of liposomal adjuvants is decisive for their interactions with the Calu-3 and A549 airway epithelial cell culture models.
European Journal of Pharmaceutics and Biopharmaceutics.
87.
2014
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chapter
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Cell-Penetrating Peptides as Carriers for Transepithelial Drug Delivery In Vitro.
Springer Nature.
2015
ISCOMs as a Vaccine Delivery System.
Springer Nature.
2015
Epithelial Permeation and Absorption Mechanisms of Biopharmaceuticals.
Springer Nature.
2014
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dataset
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Data_Sheet_1_Antimicrobial Activity of α-Peptide/β-Peptoid Lysine-Based Peptidomimetics Against Colistin-Resistant Pseudomonas aeruginosa Isolated From Cystic Fibrosis Patients.PDF.
frontiers.
2019
Data_Sheet_1_Repurposing Azithromycin and Rifampicin Against Gram-Negative Pathogens by Combination With Peptidomimetics.PDF.
frontiers.
2019
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Antimicrobial and cell-penetrating properties of penetratin analogs: Effect of sequence and secondary structure.
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism.
2013
Buccal delivery of metformin: TR146 cell culture model evaluating the use of bioadhesive chitosan discs for drug permeability enhancement.
International Journal of Pharmaceutics.
2013
Characterization of spray dried bioadhesive metformin microparticles for oromucosal administration.
European Journal of Pharmaceutics and Biopharmaceutics.
2013
Design and characterization of core–shell mPEG–PLGA composite microparticles for development of cell–scaffold constructs.
European Journal of Pharmaceutics and Biopharmaceutics.
2013
Designing CAF-adjuvanted dry powder vaccines: Spray drying preserves the adjuvant activity of CAF01.
Journal of Controlled Release.
2013
Engineering of an Inhalable DDA/TDB Liposomal Adjuvant: A Quality-by-Design Approach Towards Optimization of the Spray Drying Process.
Pharmaceutical Research.
2013
Evaluation of carrier-mediated siRNA delivery: Lessons for the design of a stem-loop qPCR-based approach for quantification of intracellular full-length siRNA.
Journal of Controlled Release.
2013
Preparation and characterization of insulin–surfactant complexes for loading into lipid‐based drug delivery systems.
Journal of Pharmaceutical Sciences.
2013
Solid lipid particles for oral delivery of peptide and protein drugs I – Elucidating the release mechanism of lysozyme during lipolysis.
European Journal of Pharmaceutics and Biopharmaceutics.
2013
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patent
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NON-AQUEOUS TOPICAL COMPOSITIONS COMPRISING A HALOGENATED SALICYLANILIDE
2019
NON-AQUEOUS TOPICAL COMPOSITIONS COMPRISING A HALOGENATED SALICYLANILIDE
2019
Non-aqueous topical compositions comprising a halogenated salicylanilide
2018
NANOPARTICLE COMPOSITIONS COMPRISING PLGA DERIVATIVES AND A LIPID
2017
NON-AQUEOUS TOPICAL COMPOSITIONS COMPRISING A HALOGENATED SALICYLANILIDE
2017
NON-AQUEOUS TOPICAL COMPOSITIONS COMPRISING A HALOGENATED SALICYLANILIDE
2017