selected publications
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academic article
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A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer.
Nature Genetics.
50.
2018
Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.
Nature Genetics.
50.
2018
Harmonising measures of knee and hip osteoarthritis in population-based cohort studies: an international study.
Osteoarthritis and Cartilage.
26.
2018
Association analysis identifies 65 new breast cancer risk loci.
Nature.
551.
2017
Body mass index and breast cancer survival: a Mendelian randomization analysis.
International Journal of Epidemiology.
46.
2017
Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk.
Nature Genetics.
49.
2017
Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.
Nature Genetics.
49.
2017
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.
Nature Genetics.
49.
2017
Interactions Between Genome-Wide Significant Genetic Variants and Circulating Concentrations of 25-Hydroxyvitamin D in Relation to Prostate Cancer Risk in the National Cancer Institute BPC3..
American Journal of Epidemiology.
185.
2017
The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers.
Cancer Epidemiology Biomarkers & Prevention.
26.
2017
Association of genetic susceptibility variants for type 2 diabetes with breast cancer risk in women of European ancestry.
Cancer Causes & Control.
27.
2016
Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation.
Nature Communications.
7.
2016
Clinical algorithms to aid osteoarthritis guideline dissemination.
Osteoarthritis and Cartilage.
24.
2016
Examining the Minimal Important Difference of Patient-reported Outcome Measures for Individuals with Knee Osteoarthritis: A Model Using the Knee Injury and Osteoarthritis Outcome Score.
The Journal of Rheumatology.
43.
2016
Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome.
Nature Communications.
7.
2016
Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-Wide Association Studies.
Gastroenterology.
151.
2016
Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent.
PLoS Medicine.
13.
2016
Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types.
Cancer Discovery.
6.
2016
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.
Nature Communications.
7.
2016
Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer.
Nature Communications.
7.
2016
Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus.
Breast Cancer Research.
18.
2016
Measuring the variation between self-reported osteoarthritis pain assessments.
Osteoarthritis and Cartilage.
24.
2016
Osteoarthritis chronic disease management programs: implementing best practice.
Osteoarthritis and Cartilage.
24.
2016
Osteoarthritis: Models for appropriate care across the disease continuum.
Best Practice & Research Clinical Rheumatology.
30.
2016
PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS.
Journal of Medical Genetics.
53.
2016
The effect of anterior cruciate ligament reconstruction on the area of subchondral bone covered by cartilage.
Osteoarthritis and Cartilage.
24.
2016
A Genome-wide Pleiotropy Scan for Prostate Cancer Risk.
European Urology.
67.
2015
Association of breast cancer risk loci with breast cancer survival.
International Journal of Cancer.
137.
2015
Characterization of Large Structural Genetic Mosaicism in Human Autosomes.
American Journal of Human Genetics.
96.
2015
Common germline polymorphisms associated with breast cancer-specific survival.
Breast Cancer Research.
17.
2015
Corrigendum to ‘2014 OARSI Guidelines for the Non-Surgical Management of Knee Osteoarthritis’ [Osteoarthritis and Cartilage 22 (2014) 363–388].
Osteoarthritis and Cartilage.
23.
2015
Examining the minimal important difference of the knee injury and osteoarthritis outcome score.
Osteoarthritis and Cartilage.
23.
2015
Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2.
Human Molecular Genetics.
24.
2015
Genetic studies of body mass index yield new insights for obesity biology.
Nature.
518.
2015
Genome-Wide Association Study of Prostate Cancer–Specific Survival.
Cancer Epidemiology Biomarkers & Prevention.
24.
2015
Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer.
Nature Genetics.
47.
2015
Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk.
Human Molecular Genetics.
24.
2015
New genetic loci link adipose and insulin biology to body fat distribution.
Nature.
518.
2015
OARSI Clinical Trials Recommendations: Design, conduct, and reporting of clinical trials for knee osteoarthritis.
Osteoarthritis and Cartilage.
23.
2015
Vitamin D–Associated Genetic Variation and Risk of Breast Cancer in the Breast and Prostate Cancer Cohort Consortium (BPC3).
Cancer Epidemiology Biomarkers & Prevention.
24.
2015
A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer.
Nature Genetics.
46.
2014
Defining the role of common variation in the genomic and biological architecture of adult human height.
Nature Genetics.
46.
2014
FTO genetic variants, dietary intake and body mass index: insights from 177 330 individuals.
Human Molecular Genetics.
23.
2014
Fine-Mapping the HOXB Region Detects Common Variants Tagging a Rare Coding Allele: Evidence for Synthetic Association in Prostate Cancer.
PLOS Genetics.
10.
2014
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
Nature Genetics.
46.
2014
Knee pain and inflammation in the infrapatellar fat pad estimated by conventional and dynamic contrast-enhanced magnetic resonance imaging in obese patients with osteoarthritis: A cross-sectional study.
Osteoarthritis and Cartilage.
22.
2014
Knee pain and inflammation in the infrapatellar fat pad estimated by conventional and dynamic contrast-enhanced magnetic resonance imaging in obese patients with osteoarthritis: a cross-sectional study.
Osteoarthritis and Cartilage.
22.
2014
OARSI guidelines for the non-surgical management of knee osteoarthritis.
Osteoarthritis and Cartilage.
22.
2014
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
Nature.
514.
2014
Response to Letter to the Editor entitled “Comments on ‘OARSI guidelines for the non-surgical management of knee osteoarthritis’”.
Osteoarthritis and Cartilage.
22.
2014
Structural changes in the knee during weight loss maintenance after a significant weight loss in obese patients with osteoarthritis: a report of secondary outcome analyses from a randomized controlled trial.
Osteoarthritis and Cartilage.
22.
2014
The association between muscle perfusion assessed by dynamic contrast enhanced magnetic resonance imaging and knee related pain and function in patients with knee osteoarthritis: an exploratory cross sectional study.
Osteoarthritis and Cartilage.
22.
2014
The effect of anterior cruciate ligament injury on bone curvature: exploratory analysis in the KANON trial.
Osteoarthritis and Cartilage.
22.
2014
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dataset
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Associations between genetically predicted BMI and breast cancer risk..
public-library-of-science.
2016
Associations of the weighted BMI-GSs with BMI and traditional breast cancer risk factors..
public-library-of-science.
2016
Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent.
public-library-of-science.
2016
Significant associations detected at p < 0.05 between breast cancer risk and BMI-related SNPs..
public-library-of-science.
2016
Fine-Mapping the HOXB Region Detects Common Variants Tagging a Rare Coding Allele: Evidence for Synthetic Association in Prostate Cancer.
public-library-of-science.
2014
Haplotype analysis for rs117576373 and rs138213197 in the subset of 5500 PrCa cases and 4923 controls from the UK and Sweden for which both had been directly genotyped..
public-library-of-science.
2014
Haplotype analysis for rs145922598 and rs138213197 in the subset of 5500 PrCa cases and 4923 controls from the UK and Sweden genotyped for rs138213197..
public-library-of-science.
2014
PrCa association information for SNPs significant at P<10−6 in the iCOGS imputed data..
public-library-of-science.
2014
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hide from search
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An Absolute Risk Model to Identify Individuals at Elevated Risk for Pancreatic Cancer in the General Population.
public-library-of-science.
2013
Association between pancreatic cancer risk and smoking, personal history of diabetes, family history of pancreatic cancer, alcohol use, body mass index, and known genetic markers..
public-library-of-science.
2013
Genetic Variation in the HSD17B1 Gene and Risk of Prostate Cancer.
public-library-of-science.
2013
Participants' Characteristics, the PanScan Consortium..
public-library-of-science.
2013
Reclassification of lifetime risk of pancreatic cancer after adding genetic information to the risk model with both genetic and non-genetic covariates..
public-library-of-science.
2013
An Absolute Risk Model to Identify Individuals at Elevated Risk for Pancreatic Cancer in the General Population.
PLoS ONE.
2013
Diabetes and risk of pancreatic cancer: a pooled analysis from the pancreatic cancer cohort consortium.
Cancer Causes & Control.
2013
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
Nature Genetics.
2013
Identification of heart rate–associated loci and their effects on cardiac conduction and rhythm disorders.
Nature Genetics.
2013
Insulin‐like growth factor pathway genes and blood concentrations, dietary protein and risk of prostate cancer in the NCI Breast and Prostate Cancer Cohort Consortium (BPC3).
International Journal of Cancer.
2013
Is increased joint loading detrimental to obese patients with knee osteoarthritis? A secondary data analysis from a randomized trial.
Osteoarthritis and Cartilage.
2013
Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits.
PLOS Genetics.
2013
Heterogeneity of Breast Cancer Associations with Five Susceptibility Loci by Clinical and Pathological Characteristics.
public-library-of-science.
2008
Multivariate Cox proportional hazards analysis of genetic polymorphisms in relation to overall survival following breast cancer diagnosis, by ER status*..
public-library-of-science.
2008
Odds ratios for breast cancer risk by lymph node involvement*..
public-library-of-science.
2008
Odds ratios for breast cancer risk by tumor grade*..
public-library-of-science.
2008
Per-allele odds ratios for breast cancer risk by estrogen receptor status..
public-library-of-science.
2008