selected publications
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academic article
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Adenylyl cyclase 6 is required for maintaining acid-base homeostasis..
Clinical Science.
132.
2018
Author Correction: The thiazide sensitive sodium chloride co-transporter NCC is modulated by site-specific ubiquitylation.
Scientific Reports.
8.
2018
Basolateral cholesterol depletion alters Aquaporin-2 post-translational modifications and disrupts apical plasma membrane targeting.
Biochemical and Biophysical Research Communications.
495.
2018
Proteomic approaches in kidney disease biomarker discovery..
American Journal of Physiology. Renal physiology.
315.
2018
RNA sequencing of kidney distal tubule cells reveals multiple mediators of chronic aldosterone action..
Physiological Genomics.
50.
2018
The murine choroid plexus epithelium expresses the 2Cl−/H+ exchanger ClC-7 and Na+/H+ exchanger NHE6 in the luminal membrane domain.
American Journal of Physiology - Cell Physiology.
314.
2018
Aquaporin-2 membrane targeting: still a conundrum..
American Journal of Physiology. Renal physiology.
312.
2017
CHIP Regulates Aquaporin-2 Quality Control and Body Water Homeostasis.
Journal of the American Society of Nephrology.
29.
2017
Functional assessment of sodium chloride cotransporter NCC mutants in polarized mammalian epithelial cells.
American Journal of Physiology. Renal physiology.
313.
2017
Hypercalcemia induces targeted autophagic degradation of aquaporin-2 at the onset of nephrogenic diabetes insipidus.
Kidney International.
91.
2017
In Primary Aldosteronism, Mineralocorticoids Influence Exosomal Sodium-Chloride Cotransporter Abundance.
Journal of the American Society of Nephrology.
28.
2017
NaCl cotransporter abundance in urinary vesicles is increased by calcineurin inhibitors and predicts thiazide sensitivity.
PLoS ONE.
12.
2017
P 149 Roles of branched-chain amino acids regulation in oxidative stress revealed by fibroblasts from classic Maple Syrup Urine Disease patients.
Free Radical Biology and Medicine.
108.
2017
Renal tubular NHE3 is required in the maintenance of water and sodium chloride homeostasis.
Kidney International.
92.
2017
Role of adenylyl cyclase 6 in the development of lithium-induced nephrogenic diabetes insipidus.
JCI Insight.
2.
2017
Temporal deletion of Aqp11 in mice is linked to the severity of cyst-like disease..
American Journal of Physiology. Renal physiology.
312.
2017
The thiazide sensitive sodium chloride co-transporter NCC is modulated by site-specific ubiquitylation.
Scientific Reports.
7.
2017
[BP.12.02] PLASMA POTASSIUM NEGATIVELY EFFECTS ABUNDANCE OF THE THAIZIDE SENSITIVE SODIUM-CHLORIDE COTRANSPORTER IN HUMANS.
Journal of Hypertension.
35.
2017
Activation of the metabolic sensor AMP-activated protein kinase inhibits aquaporin-2 function in kidney principal cells..
American Journal of Physiology. Renal physiology.
311.
2016
An immunoassay for urinary extracellular vesicles.
American Journal of Physiology. Renal physiology.
310.
2016
Autoantibodies Targeting a Collecting Duct–Specific Water Channel in Tubulointerstitial Nephritis.
Journal of the American Society of Nephrology.
27.
2016
Characterization of AQPs in Mouse, Rat, and Human Colon and Their Selective Regulation by Bile Acids.
Frontiers in Nutrition.
3.
2016
Deubiquitylation of Protein Cargo Is Not an Essential Step in Exosome Formation.
Molecular & Cellular Proteomics.
15.
2016
Mucin-mediated nanocarrier disassembly for triggered uptake of oligonucleotides as a delivery strategy for the potential treatment of mucosal tumours.
Nanoscale.
8.
2016
OS 05-06 IN PRIMARY ALDOSTERONISM, MINERALOCORTICOIDS AND POTASSIUM INFLUENCE ABUNDANCE OF THE THIAZIDE SENSITIVE SODIUM-CHLORIDE COTRANSPORTER.
Journal of Hypertension.
34.
2016
Regulation of the Water Channel Aquaporin-2 via 14-3-3θ and -ζ.
Journal of Biological Chemistry.
291.
2016
Renal aquaporins and water balance disorders.
Best Practice & Research Clinical Endocrinology & Metabolism.
30.
2016
The vascular Ca2+-sensing receptor regulates blood vessel tone and blood pressure.
American Journal of Physiology - Cell Physiology.
310.
2016
The vasopressin type 2 receptor and prostaglandin receptors EP2 and EP4 can increase aquaporin-2 plasma membrane targeting through a cAMP-independent pathway..
American Journal of Physiology. Renal physiology.
311.
2016
Urinary extracellular vesicles as markers to assess kidney sodium transport.
Current Opinion in Nephrology & Hypertension.
25.
2016
A Systems Level Analysis of Vasopressin-mediated Signaling Networks in Kidney Distal Convoluted Tubule Cells.
Scientific Reports.
5.
2015
Autophagic degradation of aquaporin-2 is an early event in hypokalemia-induced nephrogenic diabetes insipidus.
Scientific Reports.
5.
2015
Caffeine-induced diuresis and natriuresis is independent of renal tubular NHE3.
American Journal of Physiology. Renal physiology.
308.
2015
Changes in urinary excretion of water and sodium transporters during amiloride and bendroflumethiazide treatment..
World Journal of Nephrology.
4.
2015
H95 Is a pH-Dependent Gate in Aquaporin 4.
Structure.
23.
2015
Olfactory Neuroblastoma With Hyponatremia.
Journal of Clinical Oncology.
33.
2015
PP.LB03.01.
Journal of Hypertension.
33.
2015
Renal Caffeine Effects are Independent of NHE3 Abundance, Trafficking or Phosphorylation.
The FASEB Journal.
29.
2015
Role of Bile Acids for Regulation of Aquaporins in Rodent Large Intestine.
The FASEB Journal.
29.
2015
Sodium-glucose cotransport.
Current Opinion in Nephrology & Hypertension.
24.
2015
Vasopressin receptors V1a and V2 are not osmosensors.
Physiological Reports.
3.
2015
Vasopressin regulation of sodium transport in the distal nephron and collecting duct.
American Journal of Physiology. Renal physiology.
309.
2015
AQP4 plasma membrane trafficking or channel gating is not significantly modulated by phosphorylation at COOH-terminal serine residues.
American Journal of Physiology - Cell Physiology.
307.
2014
Abnormal urinary excretion of NKCC2 and AQP2 in response to hypertonic saline in chronic kidney disease: an intervention study in patients with chronic kidney disease and healthy controls.
BMC Nephrology.
15.
2014
Distal Renal Tubules Are Deficient in Aggresome Formation and Autophagy upon Aldosterone Administration.
PLoS ONE.
9.
2014
Duodenal CCK Cells from Male Mice Express Multiple Hormones Including Ghrelin.
Endocrinology.
155.
2014
Early targets of lithium in rat kidney inner medullary collecting duct include p38 and ERK1/2.
Kidney International.
86.
2014
Effects of long‐term aldosterone administration on mRNA expression levels in the renal distal nephron examined by FACS and RNA sequencing (1088.13).
The FASEB Journal.
28.
2014
Evidence for mitochondrial localization of divalent metal transporter 1 (DMT1).
The FASEB Journal.
28.
2014
Lack of adenylyl cyclase 6 causes pseudohypoparathyroidism (1181.1).
The FASEB Journal.
28.
2014
Megalin-Mediated Specific Uptake of Chitosan/siRNA Nanoparticles in Mouse Kidney Proximal Tubule Epithelial Cells Enables AQP1 Gene Silencing.
Theranostics.
4.
2014
Phosphorylation Decreases Ubiquitylation of the Thiazide-sensitive Cotransporter NCC and Subsequent Clathrin-mediated Endocytosis.
Journal of Biological Chemistry.
289.
2014
Phosphorylation and ubiquitylation are opposing processes that regulate endocytosis of the water channel aquaporin-2.
Journal of Cell Science.
127.
2014
Phosphorylation regulates clathrin‐mediated endocytosis of the thiazide‐sensitive cotransporter NCC (1181.12).
The FASEB Journal.
28.
2014
Protein Phosphatase 1 Inhibitor-1 Deficiency Reduces Phosphorylation of Renal NaCl Cotransporter and Causes Arterial Hypotension.
Journal of the American Society of Nephrology.
25.
2014
Protein phosphatase 1 Inhibitor‐1 deficiency causes hypotension and reduces the phosphorylation of renal NaCl cotransporter (892.18).
The FASEB Journal.
28.
2014
Proteomic profiling of ubiquitinated proteins in human urinary exosomes (1109.1).
The FASEB Journal.
28.
2014
Renal Phosphate Wasting in the Absence of Adenylyl Cyclase 6.
Journal of the American Society of Nephrology.
25.
2014
Renal aquaporins and water balance disorders.
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism.
1840.
2014
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chapter
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Renal Aquaporins in Health and Disease.
Springer Nature.
2016
Exosomes in Urine Biomarker Discovery.
Springer Nature.
2015
Use of Genetic Models to Study the Urinary Concentrating Mechanism.
Springer Nature.
2015
Urea Transporter Knockout Mice and Their Renal Phenotypes.
Springer Nature.
2014
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dataset
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SUMOylation Landscape
of Renal Cortical Collecting
Duct Cells.
american-chemical-society.
2019
SUMOylation Landscape
of Renal Cortical Collecting
Duct Cells.
american-chemical-society.
2019
SUMOylation Landscape
of Renal Cortical Collecting
Duct Cells.
american-chemical-society.
2019
SUMOylation Landscape
of Renal Cortical Collecting
Duct Cells.
american-chemical-society.
2019
SUMOylation Landscape
of Renal Cortical Collecting
Duct Cells.
american-chemical-society.
2019
Clinical and laboratory characteristics of the patients in study Group 1..
public-library-of-science.
2017
Clinical and laboratory characteristics of the patients in study Group 2..
public-library-of-science.
2017
NaCl cotransporter abundance in urinary vesicles is increased by calcineurin inhibitors and predicts thiazide sensitivity.
public-library-of-science.
2017
Distal Renal Tubules Are Deficient in Aggresome Formation and Autophagy upon Aldosterone Administration.
public-library-of-science.
2014
LC MS/MS analysis of proteins pulled down by H95 preferentially in samples from aldosterone treated rats but not detected in IP without beads or without antibody..
public-library-of-science.
2014
Primary antibodies used in the study..
public-library-of-science.
2014
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hide from search
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Expression and Function of the Lipocalin-2 (24p3/NGAL) Receptor in Rodent and Human Intestinal Epithelia.
public-library-of-science.
2013
Adenylyl Cyclase 6 Enhances NKCC2 Expression and Mediates Vasopressin-Induced Phosphorylation of NKCC2 and NCC.
American Journal Of Pathology.
2013
Aldosterone and angiotensin II induce protein aggregation in renal proximal tubules.
Physiological Reports.
2013
Demeclocycline attenuates hyponatremia by reducing aquaporin-2 expression in the renal inner medulla.
American Journal of Physiology. Renal physiology.
2013
Effects of ACE inhibition and ANG II stimulation on renal Na-Cl cotransporter distribution, phosphorylation, and membrane complex properties.
American Journal of Physiology - Cell Physiology.
2013
Expression and Function of the Lipocalin-2 (24p3/NGAL) Receptor in Rodent and Human Intestinal Epithelia.
PLoS ONE.
2013
Genetic ablation of aquaporin‐2 in the mouse connecting tubules results in defective renal water handling.
The Journal of Physiology.
2013
Is There a Role for PGE2 in Urinary Concentration?.
Journal of the American Society of Nephrology.
2013
K+-induced natriuresis is preserved during Na+ depletion and accompanied by inhibition of the Na+-Cl− cotransporter.
American Journal of Physiology. Renal physiology.
2013
Liver-specific Aquaporin 11 knockout mice show rapid vacuolization of the rough endoplasmic reticulum in periportal hepatocytes after amino acid feeding.
AJP Gastrointestinal and Liver Physiology.
2013
Nephrogenic Diabetes Insipidus: Essential Insights into the Molecular Background and Potential Therapies for Treatment.
Endocrine Reviews.
2013
New insights into regulated aquaporin-2 function.
Current Opinion in Nephrology & Hypertension.
2013
Phosphorylation of rat aquaporin‐4 at Ser111 is not required for channel gating.
Glia.
2013
Protection and Systemic Translocation of siRNA Following Oral Administration of Chitosan/siRNA Nanoparticles.
Molecular Therapy - Nucleic Acids.
2013
Quantitative apical membrane proteomics reveals vasopressin-induced actin dynamics in collecting duct cells.
Proceedings of the National Academy of Sciences of the United States of America.
2013
Assessment of the Effect of 24-Hour Aldosterone Administration on Protein Abundance in Fluorescence-Sorted Mouse Distal Renal Tubules by Mass Spectrometry.
Nephron.
2012