selected publications
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academic article
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A fast and novel internal calibration method for quantitative Raman measurements on aqueous solutions.
Analytical Methods.
10.
2018
Application of a Salt Coformer in a Co-Amorphous Drug System Dramatically Enhances the Glass Transition Temperature: A Case Study of the Ternary System Carbamazepine, Citric Acid, and l-Arginine..
Molecular Pharmaceutics.
15.
2018
Are phytosomes a superior nanodelivery system for the antioxidant rutin?.
International Journal of Pharmaceutics.
548.
2018
Characterization of the Hydrodynamics in a Miniaturized Dissolution Apparatus.
Journal of Pharmaceutical Sciences.
107.
2018
Development and characterization of clove oil nanoemulsions and self-microemulsifying drug delivery systems.
Journal of Drug Delivery Science and Technology.
46.
2018
Effect of composition of simulated intestinal media on the solubility of poorly soluble compounds investigated by design of experiments.
European Journal of Pharmaceutical Sciences.
111.
2018
Formulation of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine and Kolliphor® RH40 using experimental design.
Asian Journal of Pharmaceutical Sciences.
13.
2018
Hydrolysed pea proteins mitigate in vitro wheat starch digestibility.
Food Hydrocolloids.
79.
2018
In vivo anesthetic effect and mechanism of action of active compounds from Alpinia galanga oil on Cyprinus carpio (koi carp).
Aquaculture.
496.
2018
The Influence of Polymers on the Supersaturation Potential of Poor and Good Glass Formers.
Pharmaceutics.
10.
2018
The ability of two in vitro lipolysis models reflecting the human and rat gastro-intestinal conditions to predict the in vivo performance of SNEDDS dosing regimens.
European Journal of Pharmaceutics and Biopharmaceutics.
124.
2018
Using Potentiometric Free Drug Sensors to Determine the Free Concentration of Ionizable Drugs in Colloidal Systems.
Journal of Pharmaceutical Sciences.
107.
2018
Amorphous is not always better—A dissolution study on solid state forms of carbamazepine.
International Journal of Pharmaceutics.
522.
2017
Analysis of 3D Prints by X-ray Computed Microtomography and Terahertz Pulsed Imaging.
Pharmaceutical Research.
34.
2017
Bioinspired Layer-by-Layer Microcapsules Based on Cellulose Nanofibers with Switchable Permeability..
Biomacromolecules.
18.
2017
Cellulose Nanopaper and Nanofoam for Patient‐Tailored Drug Delivery.
Advanced Materials Interfaces.
4.
2017
Development of a Video-Microscopic Tool To Evaluate the Precipitation Kinetics of Poorly Water Soluble Drugs: A Case Study with Tadalafil and HPMC..
Molecular Pharmaceutics.
14.
2017
Dissolution enhancement of griseofulvin from griseofulvin-sodium dodecyl sulfate discs investigated by UV imaging.
Journal of Drug Delivery Science and Technology.
39.
2017
Efficacy of oral lipid‐based formulations of apomorphine and its diester in a Parkinson's disease rat model.
Journal of Pharmacy and Pharmacology.
69.
2017
Floating solid cellulose nanofibre nanofoams for sustained release of the poorly soluble model drug furosemide.
Journal of Pharmacy and Pharmacology.
69.
2017
From concept to in vivo testing: Microcontainers for oral drug delivery.
Journal of Controlled Release.
268.
2017
High-Throughput Lipolysis in 96-Well Plates for Rapid Screening of Lipid-Based Drug Delivery Systems.
Journal of Pharmaceutical Sciences.
106.
2017
In Vitro Model Simulating Gastro-Intestinal Digestion in the Pediatric Population (Neonates and Young Infants).
AAPS PharmSciTech.
18.
2017
In vitro and in vivo performance of monoacyl phospholipid-based self-emulsifying drug delivery systems.
Journal of Controlled Release.
255.
2017
Influence of drug load and physical form of cinnarizine in new SNEDDS dosing regimens: in vivo and in vitro evaluations.
The AAPS Journal.
19.
2017
Investigation of the Intra- and Interlaboratory Reproducibility of a Small Scale Standardized Supersaturation and Precipitation Method..
Molecular Pharmaceutics.
14.
2017
Mapping the intermediate digestion phases of human healthy intestinal contents from distal ileum and caecum at fasted and fed state conditions.
Journal of Pharmacy and Pharmacology.
69.
2017
Monoacyl phosphatidylcholine inhibits the formation of lipid multilamellar structures during in vitro lipolysis of self-emulsifying drug delivery systems.
European Journal of Pharmaceutical Sciences.
108.
2017
Self-microemulsifying drug delivery system and nanoemulsion for enhancing aqueous miscibility of Alpinia galanga oil.
PLoS ONE.
12.
2017
Solution or suspension – Does it matter for lipid based systems? In vivo studies of chase dosing lipid vehicles with aqueous suspensions of a poorly soluble drug.
European Journal of Pharmaceutics and Biopharmaceutics.
117.
2017
Studying furosemide solubilization using an in vitro model simulating gastrointestinal digestion and drug solubilization in neonates and young infants.
European Journal of Pharmaceutical Sciences.
109.
2017
Anhydrate to hydrate solid-state transformations of carbamazepine and nitrofurantoin in biorelevant media studied in situ using time-resolved synchrotron X-ray diffraction.
European Journal of Pharmaceutics and Biopharmaceutics.
100.
2016
Apomorphine and its esters: Differences in Caco-2 cell permeability and chylomicron affinity.
International Journal of Pharmaceutics.
509.
2016
Buccal absorption of diazepam is improved when administered in bioadhesive tablets—An in vivo study in conscious Göttingen mini-pigs.
International Journal of Pharmaceutics.
515.
2016
Comparison of lipases for in vitro models of gastric digestion: lipolysis using two infant formulas as model substrates.
Food & Function.
7.
2016
Corrigendum to “Formulation and characterization of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine” [Int. J. Pharm. 502 (1–2) (2016) 151–160].
International Journal of Pharmaceutics.
507.
2016
Development of a μDissolution-Permeation model with in situ drug concentration monitoring.
Journal of Drug Delivery Science and Technology.
35.
2016
Dissolution Model Development: Formulation Effects and Filter Complications.
Dissolution Technologies.
23.
2016
Effect of food intake and co-administration of placebo self-nanoemulsifying drug delivery systems on the absorption of cinnarizine in healthy human volunteers.
European Journal of Pharmaceutical Sciences.
84.
2016
Formulation and characterization of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine.
International Journal of Pharmaceutics.
502.
2016
Impact of Lipid-Based Drug Delivery Systems on the Transport and Uptake of Insulin Across Caco-2 Cell Monolayers.
Journal of Pharmaceutical Sciences.
105.
2016
In Vivo Precipitation of Poorly Soluble Drugs from Lipid-Based Drug Delivery Systems..
Molecular Pharmaceutics.
13.
2016
In vivo evaluation of lipid-based formulations for oral delivery of apomorphine and its diester prodrugs.
International Journal of Pharmaceutics.
513.
2016
Interlaboratory Validation of Small-Scale Solubility and Dissolution Measurements of Poorly Water-Soluble Drugs.
Journal of Pharmaceutical Sciences.
105.
2016
Optimizing Clinical Drug Product Performance: Applying Biopharmaceutics Risk Assessment Roadmap (BioRAM) and the BioRAM Scoring Grid.
Journal of Pharmaceutical Sciences.
105.
2016
Polymeric microcontainers improve oral bioavailability of furosemide.
International Journal of Pharmaceutics.
504.
2016
Rhamnogalacturonan-I Based Microcapsules for Targeted Drug Release.
PLoS ONE.
11.
2016
Solid cellulose nanofiber based foams – Towards facile design of sustained drug delivery systems.
Journal of Controlled Release.
244.
2016
Studying the Propensity of Compounds to Supersaturate: A Practical and Broadly Applicable Approach.
Journal of Pharmaceutical Sciences.
105.
2016
Supersaturation of zafirlukast in fasted and fed state intestinal media with and without precipitation inhibitors.
European Journal of Pharmaceutical Sciences.
91.
2016
Survival of Lactobacillus acidophilus NCFM® and Bifidobacterium lactis HN019 encapsulated in chocolate during in vitro simulated passage of the upper gastrointestinal tract.
LWT.
74.
2016
The Effect of Digestion and Drug Load on Halofantrine Absorption from Self-nanoemulsifying Drug Delivery System (SNEDDS).
The AAPS Journal.
18.
2016
Development of a high-throughput in vitro intestinal lipolysis model for rapid screening of lipid-based drug delivery systems.
European Journal of Pharmaceutics and Biopharmaceutics.
94.
2015
Elucidating the Molecular Interactions Occurring during Drug Precipitation of Weak Bases from Lipid-Based Formulations: A Case Study with Cinnarizine and a Long Chain Self-Nanoemulsifying Drug Delivery System..
Molecular Pharmaceutics.
12.
2015
Evaluation of the Use of Göttingen Minipigs to Predict Food Effects on the Oral Absorption of Drugs in Humans.
Journal of Pharmaceutical Sciences.
104.
2015
Image Analytical Approach for Needle-Shaped Crystal Counting and Length Estimation.
Crystal Growth & Design.
15.
2015
Kolliphor surfactants affect solubilization and bioavailability of fenofibrate. Studies of in vitro digestion and absorption in rats..
Molecular Pharmaceutics.
12.
2015
Lipophilic prodrugs of apomorphine I: Preparation, characterisation, and in vitro enzymatic hydrolysis in biorelevant media.
European Journal of Pharmaceutics and Biopharmaceutics.
89.
2015
Stabilisation of amorphous furosemide increases the oral drug bioavailability in rats.
International Journal of Pharmaceutics.
490.
2015
Steric and interactive barrier properties of intestinal mucus elucidated by particle diffusion and peptide permeation.
European Journal of Pharmaceutics and Biopharmaceutics.
95.
2015
Structural features of colloidal species in the human fasted upper small intestine.
Journal of Pharmacy and Pharmacology.
67.
2015
Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations. 5. Lipolysis of Representative Formulations by Gastric Lipase.
Pharmaceutical Research.
32.
2015
pH-triggered drug release from biodegradable microwells for oral drug delivery.
Biomedical Microdevices.
17.
2015
A slow cooling rate of indomethacin melt spatially confined in microcontainers increases the physical stability of the amorphous drug without influencing its biorelevant dissolution behaviour.
Drug Delivery and Translational Research.
4.
2014
Azone® Decreases the Buccal Mucosal Permeation of Diazepam in a Concentration‐Dependent Manner via a Reservoir Effect.
Journal of Pharmaceutical Sciences.
103.
2014
Cinnarizine food-effects in beagle dogs can be avoided by administration in a Self Nano Emulsifying Drug Delivery System (SNEDDS).
European Journal of Pharmaceutical Sciences.
57.
2014
Combining in vitro and in silico methods for better prediction of surfactant effects on the absorption of poorly water soluble drugs—a fenofibrate case example.
International Journal of Pharmaceutics.
473.
2014
Early pharmaceutical profiling to predict oral drug absorption: Current status and unmet needs.
European Journal of Pharmaceutical Sciences.
57.
2014
Ex Vivo Correlation of the Permeability of Metoprolol Across Human and Porcine Buccal Mucosa.
Journal of Pharmaceutical Sciences.
103.
2014
Feasibility of Capsule Endoscopy for Direct Imaging of Drug Delivery Systems in the Fasted Upper-Gastrointestinal Tract.
Pharmaceutical Research.
31.
2014
Fed and fasted state gastro-intestinal in vitro lipolysis: In vitro in vivo relations of a conventional tablet, a SNEDDS and a solidified SNEDDS.
European Journal of Pharmaceutical Sciences.
57.
2014
Impact of sodium dodecyl sulphate on the dissolution of poorly soluble drug into biorelevant medium from drug-surfactant discs.
International Journal of Pharmaceutics.
467.
2014
In Vitro Lipolysis Data Does Not Adequately Predict the In Vivo Performance of Lipid-Based Drug Delivery Systems Containing Fenofibrate.
The AAPS Journal.
16.
2014
In vitro and in vivo evaluations of the performance of an indirubin derivative, formulated in four different self‐emulsifying drug delivery systems.
Journal of Pharmacy and Pharmacology.
66.
2014
In vitro models for the prediction of in vivo performance of oral dosage forms.
European Journal of Pharmaceutical Sciences.
57.
2014
Investigating the correlation between in vivo absorption and in vitro release of fenofibrate from lipid matrix particles in biorelevant medium.
European Journal of Pharmaceutical Sciences.
51.
2014
Miniaturized Approach for Excipient Selection During the Development of Oral Solid Dosage Form.
Journal of Pharmaceutical Sciences.
103.
2014
Oral biopharmaceutics tools – Time for a new initiative – An introduction to the IMI project OrBiTo.
European Journal of Pharmaceutical Sciences.
57.
2014
Polymer-filled microcontainers for oral delivery loaded using supercritical impregnation.
Journal of Controlled Release.
173.
2014
Property profiling of biosimilar mucus in a novel mucus-containing in vitro model for assessment of intestinal drug absorption.
European Journal of Pharmaceutics and Biopharmaceutics.
87.
2014
Refining stability and dissolution rate of amorphous drug formulations.
Expert Opinion on Drug Delivery.
11.
2014
Self-nanoemulsifying drug delivery systems for oral insulin delivery: In vitro and in vivo evaluations of enteric coating and drug loading.
International Journal of Pharmaceutics.
477.
2014
Solid Lipid Particles for Oral Delivery of Peptide and Protein Drugs II – The Digestion of Trilaurin Protects Desmopressin from Proteolytic Degradation.
Pharmaceutical Research.
31.
2014
Solid Lipid Particles for Oral Delivery of Peptide and Protein Drugs III — the Effect of Fed State Conditions on the In Vitro Release and Degradation of Desmopressin.
The AAPS Journal.
16.
2014
The Biopharmaceutics Risk Assessment Roadmap for Optimizing Clinical Drug Product Performance.
Journal of Pharmaceutical Sciences.
103.
2014
Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations, Part 6: Effects of Varying Pancreatin and Calcium Levels.
The AAPS Journal.
16.
2014
Toward the Establishment of Standardized In Vitro Tests for Lipid‐Based Formulations, Part 4: Proposing a New Lipid Formulation Performance Classification System.
Journal of Pharmaceutical Sciences.
103.
2014
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chapter
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Evaluating Oral Drug Delivery Systems: Digestion Models.
Springer Nature.
2016
Evaluating Oral Drug Delivery Systems: Dissolution Models.
Springer Nature.
2016
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dataset
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Anesthetic behavioral changes of Cyprinus carpio exposed to 100, 200, 300, and 400 mg/L of AGO in SMEDDS-AGO and NE-AGO-D in comparison with EtOH-AGO..
public-library-of-science.
2017
Characterization of NE-AGO kept at different temperature for 1 month..
public-library-of-science.
2017
Characterization of NE-AGO..
public-library-of-science.
2017
Characterization of SMEDDS-AGO kept at different temperature for 1 month..
public-library-of-science.
2017
Chemical composition of AGO..
public-library-of-science.
2017
Self-microemulsifying drug delivery system and nanoemulsion for enhancing aqueous miscibility of Alpinia galanga oil.
public-library-of-science.
2017
Rhamnogalacturonan-I Based Microcapsules for Targeted Drug Release.
public-library-of-science.
2016
The composition of the SGF and SIF media (devoid of enzymes)..
public-library-of-science.
2016
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A New Approach to Dissolution Testing by UV Imaging and Finite Element Simulations.
Pharmaceutical Research.
2013
Bile salts and their importance for drug absorption.
International Journal of Pharmaceutics.
2013
Bioavailability of Cinnarizine in Dogs: Effect of SNEDDS Loading Level and Correlation with Cinnarizine Solubilization During In Vitro Lipolysis.
Pharmaceutical Research.
2013
Biorelevant characterisation of amorphous furosemide salt exhibits conversion to a furosemide hydrate during dissolution.
International Journal of Pharmaceutics.
2013
Characterization of fasted human gastric fluid for relevant rheological parameters and gastric lipase activities.
European Journal of Pharmaceutics and Biopharmaceutics.
2013
Lipid-based formulations for oral administration of poorly water-soluble drugs.
International Journal of Pharmaceutics.
2013
Optimization of self nanoemulsifying drug delivery system for poorly water-soluble drug using response surface methodology.
Drug Development and Industrial Pharmacy.
2013
Oral bioavailability of cinnarizine in dogs: Relation to SNEDDS droplet size, drug solubility and in vitro precipitation.
European Journal of Pharmaceutical Sciences.
2013
Preparation and characterization of insulin–surfactant complexes for loading into lipid‐based drug delivery systems.
Journal of Pharmaceutical Sciences.
2013
Preparation of an amorphous sodium furosemide salt improves solubility and dissolution rate and leads to a faster Tmax after oral dosing to rats.
European Journal of Pharmaceutics and Biopharmaceutics.
2013
Real-time dissolution behavior of furosemide in biorelevant media as determined by UV imaging.
Pharmaceutical Development and Technology.
2013
Solid lipid particles for oral delivery of peptide and protein drugs I – Elucidating the release mechanism of lysozyme during lipolysis.
European Journal of Pharmaceutics and Biopharmaceutics.
2013
Supersaturated Self-Nanoemulsifying Drug Delivery Systems (Super-SNEDDS) Enhance the Bioavailability of the Poorly Water-Soluble Drug Simvastatin in Dogs.
The AAPS Journal.
2013
Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations, Part 3: Understanding Supersaturation Versus Precipitation Potential During the In Vitro Digestion of Type I, II, IIIA, IIIB and IV Lipid-Based Formulations.
Pharmaceutical Research.
2013
Unravelling the ultrastructure of ascending colon fluids from patients with ulcerative colitis by cryogenic transmission electron microscopy.
Journal of Pharmacy and Pharmacology.
2013
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patent
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A CELLULAR SOLID MATERIAL DRUG CARRIER COMPRISING CELLULOSE NANOFIBERS (CNF) WHEREIN THE CELLULAR SOLID MATERIAL COMPRISES CLOSED CELLS
2019
EDIBLE SEMI-SOLID COMPOSITION FOR USE IN PATIENTS UNDERGOING ENDOSCOPY INCLUDING COLONOSCOPY
2019
EDIBLE SEMI-SOLID COMPOSITION FOR USE IN PATIENTS UNDERGOING ENDOSCOPY INCLUDING COLONOSCOPY
2019
A CELLULAR SOLID MATERIAL DRUG CARRIER COMPRISING CELLULOSE NANOFIBERS (CNF) WHEREIN THE CELLULAR SOLID MATERIAL COMPRISES CLOSED CELLS
2018
EDIBLE SEMI-SOLID COMPOSITION FOR USE IN PATIENTS UNDERGOING ENDOSCOPY INCLUDING COLONOSCOPY
2018
Edible semi-solid composition for use in patients undergoing endoscopy including colonoscopy
2018
EDIBLE SEMI-SOLID COMPOSITION FOR USE IN PATIENTS UNDERGOING ENDOSCOPY INCLUDING COLONOSCOPY
2017
EDIBLE SEMI-SOLID COMPOSITION FOR USE IN PATIENTS UNDERGOING ENDOSCOPY INCLUDING COLONOSCOPY
2017