selected publications
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academic article
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A Genetic Investigation of Sex Bias in the Prevalence of Attention-Deficit/Hyperactivity Disorder.
Biological Psychiatry.
83.
2018
ASD and schizophrenia show distinct developmental profiles in common genetic overlap with population-based social communication difficulties.
Molecular Psychiatry.
23.
2018
Amniotic Fluid INSL3 Measured During the Critical Time Window in Human Pregnancy Relates to Cryptorchidism, Hypospadias, and Phthalate Load: A Large Case–Control Study.
Frontiers in Physiology.
9.
2018
Analysis of shared heritability in common disorders of the brain.
Science.
360.
2018
Associations between vitamin D status and atherosclerosis among Inuit in Greenland.
Atherosclerosis.
268.
2018
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.
Nature Genetics.
50.
2018
Complex spatio-temporal distribution and genomic ancestry of mitochondrial DNA haplogroups in 24,216 Danes.
PLoS ONE.
13.
2018
Elevated polygenic burden for autism is associated with differential DNA methylation at birth.
Genome Medicine.
10.
2018
Exploring Cuba’s population structure and demographic history using genome-wide data.
Scientific Reports.
8.
2018
Fetal sexual dimorphism in systemic soluble fms‐like tyrosine kinase 1 among normotensive and preeclamptic women.
American Journal of Reproductive Immunology.
80.
2018
Genetics of suicide attempts in individuals with and without mental disorders: a population-based genome-wide association study.
Molecular Psychiatry.
2018
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.
Nature Genetics.
50.
2018
Genome-wide association study of Hirschsprung disease detects a novel low-frequency variant at the RET locus.
European Journal of Human Genetics.
26.
2018
Improved Lentiviral Gene Delivery to Mouse Liver by Hydrodynamic Vector Injection through Tail Vein.
Molecular Therapy - Nucleic Acids.
12.
2018
Prevalence of rearrangements in the 22q11.2 region and population-based risk of neuropsychiatric and developmental disorders in a Danish population: a case-cohort study.
The Lancet Psychiatry.
5.
2018
Quantifying the Impact of Rare and Ultra-rare Coding Variation across the Phenotypic Spectrum.
American Journal of Human Genetics.
102.
2018
Schizophrenia-associated mt-DNA SNPs exhibit highly variable haplogroup affiliation and nuclear ancestry: Bi-genomic dependence raises major concerns for link to disease.
PLoS ONE.
13.
2018
The association between neonatal vitamin D status and risk of schizophrenia.
Scientific Reports.
8.
2018
The iPSYCH2012 case–cohort sample: new directions for unravelling genetic and environmental architectures of severe mental disorders.
Molecular Psychiatry.
23.
2018
The role of genetic liability in the association of urbanicity at birth and during upbringing with schizophrenia in Denmark.
Psychological Medicine.
48.
2018
011 Hormonal and Psychosocial Factors Associated to Sexual Dysfunctions in Premenopausal Women.
Journal of Sexual Medicine.
14.
2017
5 Mitochondrial DNA Haplogroups are Associated with Psychiatric Disease: A Nation-Wide Study of 74,763 Danes.
Biological Psychiatry.
81.
2017
Androgens and Psychosocial Factors Related to Sexual Dysfunctions in Premenopausal Women∗ ∗2016 ISSM Female Sexual Dysfunction Prize.
Journal of Sexual Medicine.
14.
2017
Association of The Polygenic Risk Score For Schizophrenia With Mortality And Suicidal Behaviour - A Danish Population-Based Study.
European Neuropsychopharmacology.
27.
2017
Association of the polygenic risk score for schizophrenia with mortality and suicidal behavior - A Danish population-based study.
Schizophrenia Research.
184.
2017
COMT Val158Met and MTHFR C677T moderate risk of schizophrenia in response to childhood adversity.
Acta Psychiatrica Scandinavica.
136.
2017
Differential DNA methylation at birth associated with mental disorder in individuals with 22q11.2 deletion syndrome.
Translational Psychiatry.
7.
2017
Genome-wide association study identifies variants in HORMAD2 associated with tonsillectomy.
Journal of Medical Genetics.
54.
2017
Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity.
Nature Communications.
8.
2017
MR spectroscopy of hepatic fat and adiponectin and leptin levels during testosterone therapy in type 2 diabetes: a randomized, double-blinded, placebo-controlled trial.
European Journal of Endocrinology.
177.
2017
Monitoring steroid replacement therapy in children with congenital adrenal hyperplasia.
Journal of Pediatric Endocrinology and Metabolism.
30.
2017
Neonatal levels of adiponectin, interleukin-10 and interleukin-12 are associated with the risk of developing type 1 diabetes in childhood and adolescence: A nationwide Danish case-control study.
Clinical Immunology.
174.
2017
Neonatal vitamin D status and risk of multiple sclerosis.
Neurology.
88.
2017
Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders.
Nature Genetics.
49.
2017
RNA sequencing of archived neonatal dried blood spots.
Molecular Genetics and Metabolism Reports.
10.
2017
Testosterone therapy preserves muscle strength and power in aging men with type 2 diabetes—a randomized controlled trial.
Andrology.
5.
2017
The impact of gastric bypass surgery on sex hormones and menstrual cycles in premenopausal women.
Gynecological Endocrinology.
33.
2017
043 Hormonal and Psychosocial Characteristics of Female Sexual Dysfunction.
Journal of Sexual Medicine.
13.
2016
Alcohol-related breast cancer in postmenopausal women – effect of CYP19A1, PPARG and PPARGC1A polymorphisms on female sex-hormone levels and interaction with alcohol consumption and NSAID usage in a nested case-control study and a randomised controlled trial.
BMC Cancer.
16.
2016
An epigenetic clock for gestational age at birth based on blood methylation data.
Genome Biology.
17.
2016
Associations between Vitamin D Status and Type 2 Diabetes Measures among Inuit in Greenland May Be Affected by Other Factors.
PLoS ONE.
11.
2016
Effect of testosterone on insulin sensitivity, oxidative metabolism and body composition in aging men with type 2 diabetes on metformin monotherapy.
Diabetes Obesity and Metabolism.
18.
2016
Genetic Variation in NFKBIE Is Associated With Increased Risk of Pneumococcal Meningitis in Children.
EBioMedicine.
3.
2016
Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population.
Nature Genetics.
48.
2016
Genome-wide associations for birth weight and correlations with adult disease.
Nature.
538.
2016
High loading of polygenic risk in cases with chronic schizophrenia.
Molecular Psychiatry.
21.
2016
High-Quality Exome Sequencing of Whole-Genome Amplified Neonatal Dried Blood Spot DNA.
PLoS ONE.
11.
2016
Influence of Polygenic Risk Scores on the Association Between Infections and Schizophrenia.
Biological Psychiatry.
80.
2016
Mid-pregnancy circulating immune biomarkers in women with preeclampsia and normotensive controls.
Pregnancy Hypertension.
6.
2016
Perfluorooctane Sulfonate Concentrations in Amniotic Fluid, Biomarkers of Fetal Leydig Cell Function, and Cryptorchidism and Hypospadias in Danish Boys (1980–1996).
Environmental Health Perspectives.
124.
2016
UGT1A1*28 Genotypes and Respiratory Disease in Very Preterm Infants: A Cohort Study.
Neonatology.
109.
2016
Adipose tissue, estradiol levels, and bone health in obese men with metabolic syndrome.
European Journal of Endocrinology.
172.
2015
Amniotic Fluid Phthalate Levels and Male Fetal Gonad Function.
Epidemiology.
26.
2015
Androgens and Sexual Desire in Women.
Journal of Sexual Medicine.
12.
2015
Androgens and Women's Sexual Desire.
Journal of Sexual Medicine.
12.
2015
Anthropometry in Klinefelter Syndrome - Multifactorial Influences Due to CAG Length, Testosterone Treatment and Possibly Intrauterine Hypogonadism.
The Journal of Clinical Endocrinology & Metabolism.
100.
2015
Delay in blood sampling for routine newborn screening is associated with increased risk of schizophrenia.
Schizophrenia Research.
162.
2015
Differential effects of strength training and testosterone treatment on soluble CD36 in aging men: Possible relation to changes in body composition..
Scandinavian Journal of Clinical and Laboratory Investigation.
75.
2015
Elevated fetal steroidogenic activity in autism.
Molecular Psychiatry.
20.
2015
Heterologous Immunological Effects of Early BCG Vaccination in Low-Birth-Weight Infants in Guinea-Bissau: A Randomized-controlled Trial.
The Journal of Infectious Diseases.
211.
2015
Hormonal disturbances due to severe and mild forms of congenital adrenal hyperplasia are already detectable in neonatal life.
Acta Paediatrica.
104.
2015
Investigating interactions between early life stress and two single nucleotide polymorphisms in HSD11B2 on the risk of schizophrenia.
Psychoneuroendocrinology.
60.
2015
Levels of adiponectin and leptin at onset of type 1 diabetes have changed over time in children and adolescents.
Acta Diabetologica.
52.
2015
Mannose-Binding Lectin Gene, MBL2, Polymorphisms Do Not Increase Susceptibility to Invasive Meningococcal Disease in a Population of Danish Children.
Open Forum Infectious Diseases.
2.
2015
Neonatal Levels of Inflammatory Markers and Later Risk of Schizophrenia.
Biological Psychiatry.
77.
2015
Osteoprotegerin in Turner syndrome – relationship to aortic diameter.
Clinical Endocrinology.
82.
2015
Polygenic Risk Score, Parental Socioeconomic Status, Family History of Psychiatric Disorders, and the Risk for Schizophrenia: A Danish Population-Based Study and Meta-analysis.
JAMA Psychiatry.
72.
2015
Resveratrol reduces the levels of circulating androgen precursors but has no effect on, testosterone, dihydrotestosterone, PSA levels or prostate volume. A 4‐month randomised trial in middle‐aged men.
The Prostate.
75.
2015
Serum Leptin Measured in Early Pregnancy Is Higher in Women With Preeclampsia Compared With Normotensive Pregnant Women.
Hypertension.
65.
2015
Short QTc Interval in Males with Klinefelter Syndrome—Influence of CAG Repeat Length, Body Composition, and Testosterone Replacement Therapy.
Pacing and Clinical Electrophysiology.
38.
2015
[175-POS] Elevated serum inflammatory markers and preeclampsia: Results from a large national cohort study.
Pregnancy Hypertension.
5.
2015
A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations.
Nature Genetics.
46.
2014
Acute and Short-term Chronic Testosterone Fluctuation Effects on Glucose Homeostasis, Insulin Sensitivity, and Adiponectin: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study.
The Journal of Clinical Endocrinology & Metabolism.
99.
2014
Common variant at 16p11.2 conferring risk of psychosis.
Molecular Psychiatry.
19.
2014
Common variants associated with general and MMR vaccine–related febrile seizures.
Nature Genetics.
46.
2014
Cytokines associated with necrotizing enterocolitis in extremely-low-birth-weight infants.
Pediatric Research.
76.
2014
Decrease in Vitamin D Status in the Greenlandic Adult Population from 1987–2010.
PLoS ONE.
9.
2014
Differences in MBL levels between juvenile patients newly diagnosed with type 1 diabetes and their healthy siblings.
Molecular Immunology.
62.
2014
Extreme Neonatal Hyperbilirubinemia and a Specific Genotype: A Population-Based Case-Control Study.
Pediatrics.
134.
2014
Fetal Gender and Several Cytokines Are Associated with the Number of Fetal Cells in Maternal Blood – An Observational Study.
PLoS ONE.
9.
2014
Genome-wide association analyses identify variants in developmental genes associated with hypospadias.
Nature Genetics.
46.
2014
Genome-wide study of association and interaction with maternal cytomegalovirus infection suggests new schizophrenia loci.
Molecular Psychiatry.
19.
2014
Investigation of the involvement of MIR185 and its target genes in the development of schizophrenia..
Journal of Psychiatry and Neuroscience.
39.
2014
Mannose-Binding Lectin Gene, MBL2, Polymorphisms Are Not Associated With Susceptibility to Invasive Pneumococcal Disease in Children.
Clinical Infectious Diseases.
59.
2014
Neuropsychology and brain morphology in Klinefelter syndrome – the impact of genetics.
Andrology.
2.
2014
Systemic Effects of Wood Smoke in a Short-Term Experimental Exposure Study of Atopic Volunteers.
Journal of Occupational and Environmental Medicine.
56.
2014
The prevalence of polycystic ovary syndrome in a normal population according to the Rotterdam criteria versus revised criteria including anti-Müllerian hormone.
Human Reproduction.
29.
2014
The relationship between health-related quality of life, obesity and testosterone levels in older men.
Age and Ageing.
43.
2014
UGT1A1*28 polymorphism and acute lymphoblastic leukemia in children: a Danish case–control study.
Pediatric Research.
76.
2014
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chapter
-
dataset
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Supplementary Tables 1-8 from Variable DNA methylation in neonates mediates the association between prenatal smoking and birth weight.
the-royal-society.
2019
Supplementary Tables 1-8 from Variable DNA methylation in neonates mediates the association between prenatal smoking and birth weight.
the-royal-society.
2019
Additional file 3: of Elevated polygenic burden for autism is associated with differential DNA methylation at birth.
springer-nature.
2018
Additional file 4: of Elevated polygenic burden for autism is associated with differential DNA methylation at birth.
springer-nature.
2018
Association of SNPs with SZ in Danish nuclear ancestry and a specific mtDNA haplogroup..
public-library-of-science.
2018
Complex spatio-temporal distribution and genomic ancestry of mitochondrial DNA haplogroups in 24,216 Danes.
public-library-of-science.
2018
Distribution of mtDNA haplogroups constituting the macro-hg R..
public-library-of-science.
2018
Distribution of mtDNA haplogroups contained within the N and M macro hgs..
public-library-of-science.
2018
Distribution of mtDNA macro hgs L0-L6, M, N and R..
public-library-of-science.
2018
Distribution of mtDNA sub-haplogroups of H, V, J, T, K, and U, the most frequent European haplogroups..
public-library-of-science.
2018
Distribution of the most frequent haplogroups in the five administrative regions of Denmark..
public-library-of-science.
2018
Distributions of the most frequent haplogroups in the period 1981–1986 and 2000–2005..
public-library-of-science.
2018
Schizophrenia associated mtDNA SNPs, their frequency, mtDNA hg association, and link with disease..
public-library-of-science.
2018
Schizophrenia-associated mt-DNA SNPs exhibit highly variable haplogroup affiliation and nuclear ancestry: Bi-genomic dependence raises major concerns for link to disease.
public-library-of-science.
2018
Additional file 2: of An epigenetic clock for gestational age at birth based on blood methylation data.
springer-nature.
2016
Additional file 3: of An epigenetic clock for gestational age at birth based on blood methylation data.
springer-nature.
2016
Additional file 4: of An epigenetic clock for gestational age at birth based on blood methylation data.
springer-nature.
2016
Additional file 5: of An epigenetic clock for gestational age at birth based on blood methylation data.
springer-nature.
2016
Additional file 6: of An epigenetic clock for gestational age at birth based on blood methylation data.
springer-nature.
2016
Additional file 8: of An epigenetic clock for gestational age at birth based on blood methylation data.
springer-nature.
2016
Association between serum 25(OH)D3 (nmol/L) and glucose intolerance in 2005–2010..
public-library-of-science.
2016
Association between serum 25(OH)D3 (nmol/L) and measures of glucose homeostasis in 2005–2010..
public-library-of-science.
2016
Characteristics of the study population in 1987 (N = 330) and 2005–2010 (N = 2877)..
public-library-of-science.
2016
High-Quality Exome Sequencing of Whole-Genome Amplified Neonatal Dried Blood Spot DNA.
public-library-of-science.
2016
Supplementary Material for: UGT1A1*28 Genotypes and Respiratory Disease in Very Preterm Infants: A Cohort Study.
karger-publishers.
2015
Decrease in Vitamin D Status in the Greenlandic Adult Population from 1987–2010.
public-library-of-science.
2014
Predictors of serum 25(OH)D3 (nmol/L) expressed as percentage change per defined unit change in the explanatory variablea..
public-library-of-science.
2014
Serum 25(OH)D3 (nmol/L) among 306 individuals examined in May-June 1987 and 745 individuals examined in May-June 2005–2010 by gender and age groupsa..
public-library-of-science.
2014
Serum 25(OH)D3 (nmol/L) and prevalence of concentrations above 50 nmol/L, 25–50 nmol/L and less than 25 nmol/L among 2877 individuals included in the IHIT-study, 2005–2010, by gender and age groups..
public-library-of-science.
2014
Table S1 - Fetal Gender and Several Cytokines Are Associated with the Number of Fetal Cells in Maternal Blood – An Observational Study.
public-library-of-science.
2014
The median and 25–75th percentile of different continuous variables and their correlation isolated fetal cells in 30 ml maternal blood..
public-library-of-science.
2014
The number of isolated fetal cells in 30 ml maternal blood in relation to fetal gender and multipara..
public-library-of-science.
2014
The number of isolated fetal cells in 30 ml maternal blood in relation to selected cytokines..
public-library-of-science.
2014
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hide from search
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Odds ratio (OR) for PPD by covariates and distribution of covariates amongst cases and controls..
public-library-of-science.
2013
Odds ratio for PPD by six levels of vitamin D with adjustment for different potential confounders..
public-library-of-science.
2013
Table S1 - Vitamin D Status during Pregnancy and the Risk of Subsequent Postpartum Depression: A Case-Control Study.
public-library-of-science.
2013
Amniotic fluid inflammatory cytokines: Potential markers of immunologic dysfunction in autism spectrum disorders.
The World Journal of Biological Psychiatry.
2013
Archived neonatal dried blood spot samples can be used for accurate whole genome and exome-targeted next-generation sequencing.
Molecular Genetics and Metabolism.
2013
Independent Effects of Testosterone on Lipid Oxidation and VLDL-TG Production A Randomized, Double-Blind, Placebo-Controlled, Crossover Study.
Diabetes.
2013
N-3 Polyunsaturated Fatty Acids, Body Fat and Inflammation.
Obesity Facts.
2013
Neonatal chemokine levels and risk of autism spectrum disorders: Findings from a Danish historic birth cohort follow-up study.
Cytokine.
2013
Neonatal levels of neurotrophic factors and risk of autism spectrum disorders.
Acta Psychiatrica Scandinavica.
2013
New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism.
Nature Genetics.
2013
Similar reference intervals for total testosterone in healthy young and elderly men: results from the Odense Androgen Study.
Clinical Endocrinology.
2013
Strength Training and Testosterone Treatment Have Opposing Effects on Migration Inhibitor Factor Levels in Ageing Men.
Mediators of Inflammation.
2013
Vitamin D Status during Pregnancy and the Risk of Subsequent Postpartum Depression: A Case-Control Study.
PLoS ONE.
2013
Osteoprotegerin levels decrease during testosterone therapy in aging men and are associated with changed distribution of regional fat..
Hormone and Metabolic Research.
2012
Characteristics according to FTO rs9939609 given as mean (S.D.) of the two study cohorts representing, respectively, a random sample of Danish male draftees and all obese male draftees..
public-library-of-science.
2011
Effect estimates* with 95% CIs based on regression analyses of the inflammatory markers per the unit of the covariates..
public-library-of-science.
2011
Geometric mean (95% confidence intervals) of the inflammatory markers according to FTO rs9939609 genotype for the two cohorts combined..
public-library-of-science.
2011
Influences of the Common FTO rs9939609 Variant on Inflammatory Markers Throughout a Broad Range of Body Mass Index.
public-library-of-science.
2011
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preprint
-
A Major Role for Common Genetic Variation in Anxiety Disorders.
bioRxiv.
2017
A genetic investigation of sex bias in the prevalence of attention deficit hyperactivity disorder.
bioRxiv.
2017
A genome-wide association study for shared risk across major psychiatric disorders in a nation-wide birth cohort implicates fetal neurodevelopment as a key mediator.
bioRxiv.
2017
Common risk variants identified in autism spectrum disorder.
bioRxiv.
2017
Complex spatio-temporal distribution and genogeographic affinity of mitochondrial DNA haplogroups in 24,216 Danes.
bioRxiv.
2017
Discovery of the first genome-wide significant risk loci for ADHD.
bioRxiv.
2017
Elevated polygenic burden for autism is associated with differential DNA methylation at birth.
bioRxiv.
2017
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depressive disorder.
bioRxiv.
2017
Genome-wide association study identifies 30 Loci Associated with Bipolar Disorder.
bioRxiv.
2017
Genome-wide association study implicates CHRNA2 in cannabis use disorder.
bioRxiv.
2017
Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes.
bioRxiv.
2017
Mitochondrial DNA SNPs associated with Schizophrenia exhibit Highly Variable Inter-allelic Haplogroup Affiliation and Nuclear Genogeographic Affinity: Bi-Genomic Linkage Disequilibrium raises Major Concerns for Link to Disease.
bioRxiv.
2017
Quantifying the impact of rare and ultra-rare coding variation across the phenotypic spectrum.
bioRxiv.
2017
The iPSYCH2012 case-cohort sample: New directions for unravelling genetic and environmental architectures of severe mental disorders.
bioRxiv.
2017
A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects: CNV Analysis Group and the Schizophrenia Working Group of the Psychiatric Genomics Consortium.
bioRxiv.
2016
Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders.
bioRxiv.
2016
Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population.
bioRxiv.
2015