selected publications
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academic article
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Adult height is associated with increased risk of ovarian cancer: a Mendelian randomisation study.
British Journal of Cancer.
118.
2018
Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.
Nature Genetics.
50.
2018
Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations.
Human Mutation.
39.
2018
MyD88 and TLR4 Expression in Epithelial Ovarian Cancer.
Mayo Clinic Proceedings.
93.
2018
Prostate-specific antigen velocity in a prospective prostate cancer screening study of men with genetic predisposition.
British Journal of Cancer.
118.
2018
The BRCA2 c.68‐7T > A variant is not pathogenic: A model for clinical calibration of spliceogenicity.
Human Mutation.
39.
2018
Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility.
PLoS ONE.
13.
2018
rs495139 in the TYMS-ENOSF1 Region and Risk of Ovarian Carcinoma of Mucinous Histology.
International Journal of Molecular Sciences.
19.
2018
Association analysis identifies 65 new breast cancer risk loci.
Nature.
551.
2017
BRCA2 Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer.
Cancer Research.
77.
2017
Body mass index and breast cancer survival: a Mendelian randomization analysis.
International Journal of Epidemiology.
46.
2017
Dose-Response Association of CD8+ Tumor-Infiltrating Lymphocytes and Survival Time in High-Grade Serous Ovarian Cancer.
JAMA Oncology.
3.
2017
Enrichment of putative PAX8 target genes at serous epithelial ovarian cancer susceptibility loci.
British Journal of Cancer.
116.
2017
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.
Nature Genetics.
49.
2017
No Evidence That Genetic Variation in the Myeloid-Derived Suppressor Cell Pathway Influences Ovarian Cancer Survival.
Cancer Epidemiology Biomarkers & Prevention.
26.
2017
Adult body mass index and risk of ovarian cancer by subtype: a Mendelian randomization study.
International Journal of Epidemiology.
45.
2016
Assessing the genetic architecture of epithelial ovarian cancer histological subtypes.
Human Genetics.
135.
2016
Association of genetic susceptibility variants for type 2 diabetes with breast cancer risk in women of European ancestry.
Cancer Causes & Control.
27.
2016
Association of vitamin D levels and risk of ovarian cancer: a Mendelian randomization study.
International Journal of Epidemiology.
45.
2016
Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.
Nature Genetics.
48.
2016
Exome genotyping arrays to identify rare and low frequency variants associated with epithelial ovarian cancer risk..
Human Molecular Genetics.
25.
2016
Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs).
Scientific Reports.
6.
2016
Fine-Mapping of the 1p11.2 Breast Cancer Susceptibility Locus.
PLoS ONE.
11.
2016
Fine‐scale mapping of 8q24 locus identifies multiple independent risk variants for breast cancer.
International Journal of Cancer.
139.
2016
Genetic predisposition to ductal carcinoma in situ of the breast.
Breast Cancer Research.
18.
2016
Genetic variation in the immunosuppression pathway genes and breast cancer susceptibility: a pooled analysis of 42,510 cases and 40,577 controls from the Breast Cancer Association Consortium.
Human Genetics.
135.
2016
Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent.
PLoS Medicine.
13.
2016
Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types.
Cancer Discovery.
6.
2016
Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer.
Nature Communications.
7.
2016
Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus.
Breast Cancer Research.
18.
2016
Investigation of Exomic Variants Associated with Overall Survival in Ovarian Cancer.
Cancer Epidemiology Biomarkers & Prevention.
25.
2016
Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2.
Breast Cancer Research.
18.
2016
No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.
Gynecologic Oncology.
141.
2016
No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: implications for gene panel testing.
Journal of Medical Genetics.
53.
2016
PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS.
Journal of Medical Genetics.
53.
2016
Patient survival and tumor characteristics associated with CHEK2:p.I157T – findings from the Breast Cancer Association Consortium.
Breast Cancer Research.
18.
2016
RAD51B in Familial Breast Cancer.
PLoS ONE.
11.
2016
Assessing Associations between the AURKA-HMMR-TPX2-TUBG1 Functional Module and Breast Cancer Risk in BRCA1/2 Mutation Carriers.
PLoS ONE.
10.
2015
Association of Type and Location of BRCA1 and BRCA2 Mutations With Risk of Breast and Ovarian Cancer.
JAMA.
313.
2015
Candidate Genetic Modifiers for Breast and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers.
Cancer Epidemiology Biomarkers & Prevention.
24.
2015
Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer.
Nature Communications.
6.
2015
Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk.
PLoS ONE.
10.
2015
Common Genetic Variation in Circadian Rhythm Genes and Risk of Epithelial Ovarian Cancer (EOC).
Journal of Genetics and Genome Research.
2.
2015
Common germline polymorphisms associated with breast cancer-specific survival.
Breast Cancer Research.
17.
2015
Evaluating the ovarian cancer gonadotropin hypothesis: A candidate gene study.
Gynecologic Oncology.
136.
2015
Fine-Scale Mapping of the 4q24 Locus Identifies Two Independent Loci Associated with Breast Cancer Risk.
Cancer Epidemiology Biomarkers & Prevention.
24.
2015
Genome-Wide Association Study of Prostate Cancer–Specific Survival.
Cancer Epidemiology Biomarkers & Prevention.
24.
2015
Genome-wide Analysis Identifies Novel Loci Associated with Ovarian Cancer Outcomes: Findings from the Ovarian Cancer Association Consortium.
Clinical Cancer Research.
21.
2015
Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer.
Nature Genetics.
47.
2015
Identification of six new susceptibility loci for invasive epithelial ovarian cancer.
Nature Genetics.
47.
2015
Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.
Nature Genetics.
47.
2015
Network-Based Integration of GWAS and Gene Expression Identifies a HOX-Centric Network Associated with Serous Ovarian Cancer Risk.
Cancer Epidemiology Biomarkers & Prevention.
24.
2015
Obesity, Aspirin, and Risk of Colorectal Cancer in Carriers of Hereditary Colorectal Cancer: A Prospective Investigation in the CAPP2 Study.
Journal of Clinical Oncology.
33.
2015
A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46 450 cases and 42 461 controls from the breast cancer association consortium.
Human Molecular Genetics.
23.
2014
Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers.
Breast Cancer Research.
16.
2014
DNA Glycosylases Involved in Base Excision Repair May Be Associated with Cancer Risk in BRCA1 and BRCA2 Mutation Carriers.
PLOS Genetics.
10.
2014
FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium.
British Journal of Cancer.
110.
2014
Functional Screening Identifies miRNAs Influencing Apoptosis and Proliferation in Colorectal Cancer.
PLoS ONE.
9.
2014
Genetic Predisposition to In Situ and Invasive Lobular Carcinoma of the Breast.
PLOS Genetics.
10.
2014
Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study.
Breast Cancer Research.
16.
2014
Genome-wide association study of subtype-specific epithelial ovarian cancer risk alleles using pooled DNA.
Human Genetics.
133.
2014
Methylation of the BRCA1 promoter in peripheral blood DNA is associated with triple-negative and medullary breast cancer.
Breast Cancer Research and Treatment.
148.
2014
Targeted Prostate Cancer Screening in BRCA1 and BRCA2 Mutation Carriers: Results from the Initial Screening Round of the IMPACT Study.
European Urology.
66.
2014
Variation in NF-κB Signaling Pathways and Survival in Invasive Epithelial Ovarian Cancer.
Cancer Epidemiology Biomarkers & Prevention.
23.
2014
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dataset
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Association of variants in small GTPase genes with epithelial ovarian cancer risk (p-value<10−4) and functional annotation..
public-library-of-science.
2018
Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility.
public-library-of-science.
2018
Associations between genetically predicted BMI and breast cancer risk..
public-library-of-science.
2016
Associations of the weighted BMI-GSs with BMI and traditional breast cancer risk factors..
public-library-of-science.
2016
Estimated haplotype frequencies and haplotype-specific ORs among the BCAC dataset..
public-library-of-science.
2016
Fine-Mapping of the 1p11.2 Breast Cancer Susceptibility Locus.
public-library-of-science.
2016
Frequencies and ORs for the SNPs rs2588809, rs1314913, and rs999737 for all breast cancer cases, familial cases and ER-positive and -negative cases in the BCAC dataset..
public-library-of-science.
2016
Frequencies and ORs for the c.541C>T mutation among the different patient subgroups in the Helsinki, Tampere, Oulu, and Belarus series..
public-library-of-science.
2016
Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent.
public-library-of-science.
2016
RAD51B in Familial Breast Cancer.
public-library-of-science.
2016
Significant associations detected at p < 0.05 between breast cancer risk and BMI-related SNPs..
public-library-of-science.
2016
Two independent association signals at the 1p11.2 locus: Association results for breast cancer risk among European women in BCAC, by tumor characteristic..
public-library-of-science.
2016
Two independent association signals at the 1p11.2 locus: Association results for breast cancer risk among women in BCAC, by ancestry..
public-library-of-science.
2016
Variants identified in the screening of the RAD51B gene (RefSeq NM_133509.3)..
public-library-of-science.
2016
Assessing Associations between the AURKA-HMMR-TPX2-TUBG1 Functional Module and Breast Cancer Risk in BRCA1/2 Mutation Carriers.
public-library-of-science.
2015
Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk.
public-library-of-science.
2015
Potential GxG associated with breast cancer risk in BRCA1/2 mutation carriers..
public-library-of-science.
2015
The most significant SNPs in the transport pathway genes and risk of EOC by histology, invasiveness, and race/ethnicity1..
public-library-of-science.
2015
Top SNPs associated with SER EOC across racial groups..
public-library-of-science.
2015
Associations with breast and ovarian cancer risk for SNPs observed at p-trend<0.05 in stage II of the experiment..
public-library-of-science.
2014
DNA Glycosylases Involved in Base Excision Repair May Be Associated with Cancer Risk in BRCA1 and BRCA2 Mutation Carriers.
public-library-of-science.
2014
Expression of known direct miR-375 targets..
public-library-of-science.
2014
Functional Screening Identifies miRNAs Influencing Apoptosis and Proliferation in Colorectal Cancer.
public-library-of-science.
2014
Summary of patients and sample characteristics..
public-library-of-science.
2014
The most differentially expressed miRNAs in stage II colorectal adenocarcinomas and their ability to induce phenotypic changes in the high-throughput analysis..
public-library-of-science.
2014
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hide from search
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Analysis of associations with breast and ovarian cancer risk simultaneously (competing risks analysis) for SNPs found to be associated with breast or ovarian cancer..
public-library-of-science.
2013
Associations with SNPs at the novel 17q21 region with ovarian cancer risk for BRCA1 and BRCA2 mutation carriers..
public-library-of-science.
2013
Associations with breast and ovarian cancer risk for SNPs found to be associated with risk at all 3 stages of the experiment..
public-library-of-science.
2013
Associations with breast or ovarian cancer risk for loci previously reported to be associated with cancer risk for BRCA1 mutation carriers..
public-library-of-science.
2013
Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk.
public-library-of-science.
2013
A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease.
Human Molecular Genetics.
2013
Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer.
Nature Communications.
2013
GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.
Nature Genetics.
2013
Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk.
PLOS Genetics.
2013
Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31.
Nature Communications.
2013
MiRNA‐362‐3p induces cell cycle arrest through targeting of E2F1, USF2 and PTPN1 and is associated with recurrence of colorectal cancer.
International Journal of Cancer.
2013
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer.
Nature Genetics.
2013