selected publications
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academic article
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Immunization with Recombinant Plasmodium falciparum Erythrocyte Membrane Protein 1 CIDRα1 Domains Induces Domain Subtype Inhibitory Antibodies.
Infection and Immunity.
86.
2018
Supporting capacity for research on malaria in Africa.
BMJ Global Health.
3.
2018
The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner.
Nature Communications.
9.
2018
Virus-like particle display of HER2 induces potent anti-cancer responses.
OncoImmunology.
7.
2018
Burkitt lymphoma expresses oncofetal chondroitin sulfate without being a reservoir for placental malaria sequestration.
International Journal of Cancer.
140.
2017
Cellulose filtration of blood from malaria patients for improving ex vivo growth of Plasmodium falciparum parasites.
Malaria Journal.
16.
2017
Comparison of functional assays used in the clinical development of a placental malaria vaccine.
Vaccine.
35.
2017
Improving the malaria transmission-blocking activity of a Plasmodium falciparum 48/45 based vaccine antigen by SpyTag/SpyCatcher mediated virus-like display.
Vaccine.
35.
2017
Parasites Causing Cerebral Falciparum Malaria Bind Multiple Endothelial Receptors and Express EPCR and ICAM-1-Binding PfEMP1.
The Journal of Infectious Diseases.
215.
2017
Plasmodium falciparum Infection Early in Pregnancy has Profound Consequences for Fetal Growth..
The Journal of Infectious Diseases.
216.
2017
Pre-clinical and clinical development of the first placental malaria vaccine.
Expert Review of Vaccines.
16.
2017
Structure-Guided Identification of a Family of Dual Receptor-Binding PfEMP1 that Is Associated with Cerebral Malaria.
Cell Host & Microbe.
21.
2017
The Severity of Plasmodium falciparum Infection Is Associated with Transcript Levels of var Genes Encoding Endothelial Protein C Receptor-Binding P. falciparum Erythrocyte Membrane Protein 1.
Infection and Immunity.
85.
2017
Adhesion of Plasmodium falciparum infected erythrocytes in ex vivo perfused placental tissue: a novel model of placental malaria.
Malaria Journal.
15.
2016
Bacterial superglue enables easy development of efficient virus-like particle based vaccines.
Journal of Nanobiotechnology.
14.
2016
Bacterial superglue generates a full-length circumsporozoite protein virus-like particle vaccine capable of inducing high and durable antibody responses.
Malaria Journal.
15.
2016
Differences in PfEMP1s recognized by antibodies from patients with uncomplicated or severe malaria.
Malaria Journal.
15.
2016
Oncofetal Chondroitin Sulfate Glycosaminoglycans Are Key Players in Integrin Signaling and Tumor Cell Motility.
Molecular Cancer Research.
14.
2016
Placental Sequestration of Plasmodium falciparum Malaria Parasites Is Mediated by the Interaction Between VAR2CSA and Chondroitin Sulfate A on Syndecan-1.
PLoS Pathogens.
12.
2016
Plasma Ang2 and ADAM17 levels are elevated during clinical malaria; Ang2 level correlates with severity and expression of EPCR-binding PfEMP1.
Scientific Reports.
6.
2016
Plasmodium falciparum var genes expressed in children with severe malaria encode CIDRα1 domains.
EMBO Molecular Medicine.
8.
2016
Real-time and label free determination of ligand binding-kinetics to primary cancer tissue specimens; a novel tool for the assessment of biomarker targeting.
Sensing and Bio-Sensing Research.
9.
2016
A Novel Virus-Like Particle Based Vaccine Platform Displaying the Placental Malaria Antigen VAR2CSA.
PLoS ONE.
10.
2015
Genetic Diversity and Protective Efficacy of the RTS,S/AS01 Malaria Vaccine.
New England Journal of Medicine.
373.
2015
Haplotypes of the endothelial protein C receptor (EPCR) gene are not associated with severe malaria in Tanzania.
Malaria Journal.
14.
2015
IgG Antibodies to Endothelial Protein C Receptor-Binding Cysteine-Rich Interdomain Region Domains of Plasmodium falciparum Erythrocyte Membrane Protein 1 Are Acquired Early in Life in Individuals Exposed to Malaria.
Infection and Immunity.
83.
2015
Protein C system defects inflicted by the malaria parasite protein PfEMP1 can be overcome by a soluble EPCR variant..
Thrombosis and Haemostasis.
114.
2015
Structural Conservation Despite Huge Sequence Diversity Allows EPCR Binding by the PfEMP1 Family Implicated in Severe Childhood Malaria.
Cell Host & Microbe.
17.
2015
Targeting Human Cancer by a Glycosaminoglycan Binding Malaria Protein.
Cancer Cell.
28.
2015
The Influence of Sub-Unit Composition and Expression System on the Functional Antibody Response in the Development of a VAR2CSA Based Plasmodium falciparum Placental Malaria Vaccine.
PLoS ONE.
10.
2015
DNA secondary structures are associated with recombination in major Plasmodium falciparum variable surface antigen gene families.
Nucleic Acids Research.
42.
2014
Disruption of EPCR-Dependent Functions By Plasmodium Falciparum Erythrocyte Membrane Protein 1 (PfEMP1) Can be Rescued By a Soluble EPCR Variant.
Blood.
124.
2014
Utilizing Nanobody Technology to Target Non-Immunodominant Domains of VAR2CSA.
PLoS ONE.
9.
2014
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dataset
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Characteristics of 736 women..
public-library-of-science.
2019
Factors affecting the chance of conceiving within 180 days..
public-library-of-science.
2019
Marked reduction in fertility among African women with urogenital infections: A prospective cohort study.
public-library-of-science.
2019
Multivariate model for factors significantly affecting change of conceiving..
public-library-of-science.
2019
Placental CSPGs, identified by mass spectrometry, from placenta extract or syncytiotrophoblast membrane vesicles binding rVAR2 in pull-downs experiments..
public-library-of-science.
2016
Placental Sequestration of Plasmodium falciparum Malaria Parasites Is Mediated by the Interaction Between VAR2CSA and Chondroitin Sulfate A on Syndecan-1.
public-library-of-science.
2016
Serum endpoint titers (median {25 and 75 percentiles}) obtained with the different immunogens..
public-library-of-science.
2015
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hide from search
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Additional file 1 of Immunization with virus-like particles conjugated to CIDRα1 domain of Plasmodium falciparum erythrocyte membrane protein 1 induces inhibitory antibodies.
springer-nature.
2020
Characteristics of the 876 mother-newborn pairs eligible for analysis stratified by gravidity..
public-library-of-science.
2013
Different growth patterns after a malaria infection..
public-library-of-science.
2013
Fetal weight, fetal growth, birth weight and gestational age at delivery..
public-library-of-science.
2013
Malaria and Fetal Growth Alterations in the 3rd Trimester of Pregnancy: A Longitudinal Ultrasound Study.
public-library-of-science.
2013
Patterns of fetal growth following a malaria infection evaluated using Δz for the individual offspring..
public-library-of-science.
2013
Proportion of primi and secundigravidae with a fetal weight gain belonging to the lowest 25%, stratified by malaria positivity..
public-library-of-science.
2013
The effect of malaria among primi- and secundigravidae on z-score of birth weight, relative weight gain from ANV3 to ANV4, ANV4 to delivery, and ANV3 to delivery..
public-library-of-science.
2013
The effect of malaria during pregnancy on fetal growth, given as relative fetal growth (g/week*kg), among primi- and secundigravidae..
public-library-of-science.
2013
A Novel Domain Cassette Identifies Plasmodium falciparum PfEMP1 Proteins Binding ICAM-1 and Is a Target of Cross-Reactive, Adhesion-Inhibitory Antibodies.
The Journal of Immunology.
2013
Expression of the Domain Cassette 8 Plasmodium falciparum Erythrocyte Membrane Protein 1 Is Associated with Cerebral Malaria in Benin.
PLoS ONE.
2013
Human genetic polymorphisms in the Knops blood group are not associated with a protective advantage against Plasmodium falciparum malaria in Southern Ghana.
Malaria Journal.
2013
Malaria and Fetal Growth Alterations in the 3rd Trimester of Pregnancy: A Longitudinal Ultrasound Study.
PLoS ONE.
2013
Multilaboratory Approach to Preclinical Evaluation of Vaccine Immunogens for Placental Malaria.
Infection and Immunity.
2013
PfSETvs methylation of histone H3K36 represses virulence genes in Plasmodium falciparum.
Nature.
2013
Plasmodium falciparum Expressing Domain Cassette 5 Type PfEMP1 (DC5-PfEMP1) Bind PECAM1.
PLoS ONE.
2013
Plasmodium falciparum Mutant Haplotype Infection during Pregnancy Associated with Reduced Birthweight, Tanzania - Volume 19, Number 9—September 2013 - Emerging Infectious Diseases journal - CDC.
Emerging Infectious Diseases.
2013
Severe malaria is associated with parasite binding to endothelial protein C receptor.
Nature.
2013
Characteristics of the 583 newborns included in the FW charts and their mothers..
public-library-of-science.
2012
Development of a Fetal Weight Chart Using Serial Trans-Abdominal Ultrasound in an East African Population: A Longitudinal Observational Study.
public-library-of-science.
2012
Weight percentiles for the weight chart..
public-library-of-science.
2012
Differential Induction of Functional IgG Using the Plasmodium falciparum Placental Malaria Vaccine Candidate VAR2CSA.
public-library-of-science.
2011
Plasmodium falciparum Erythrocyte Membrane Protein 1 Diversity in Seven Genomes – Divide and Conquer.
public-library-of-science.
2010
Confirmation by real-time quantitative rt-PCR of in vivo expression of mRNA for 13 different genes, compared with that in 3D7 in vitro reference..
public-library-of-science.
2008
Plasmodium falciparum Transcriptome Analysis Reveals Pregnancy Malaria Associated Gene Expression.
public-library-of-science.
2008
Structural Insight into Epitopes in the Pregnancy-Associated Malaria Protein VAR2CSA.
public-library-of-science.
2008
Total number of genes that were differentially expressed in in vivo parasite isolates compared with expression in in vitro 3D7 reference..
public-library-of-science.
2008
Epitope Mapping and Topographic Analysis of VAR2CSA DBL3X Involved in P. falciparum Placental Sequestration.
public-library-of-science.
2006
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patent
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VIRUS LIKE PARTICLE WITH EFFICIENT EPITOPE DISPLAY
2019
VIRUS LIKE PARTICLE WITH EFFICIENT EPITOPE DISPLAY
2018
VIRUS-LIKE PARTICLE WITH EFFICIENT EPITOPE DISPLAY
2018
VIRUS-LIKE PARTICLE WITH EFFICIENT EPITOPE DISPLAY
2018
VIRUSUAL PARTICLES WITH EFFICIENT EPITOPHONE
2018
Virus-like particle with efficient epitope display
2018
VIRUS-LIKE PARTICLE WITH EFFICIENT EPITOPE DISPLAY
2017
Virus like particle with efficient epitope display
2017
Virus-like particle with efficient epitope display
2017
VIRUS-LIKE PARTICLE WITH EFFICIENT EPITOPE DISPLAY
2016
VIRUS-LIKE PARTICLE WITH EFFICIENT EPITOPE DISPLAY
2016
COMPOUNDS USEFUL IN THE DIAGNOSIS AND TREATMENT OF PREGNANCY-ASSOCIATED MALARIA
2014