selected publications
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academic article
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Activation of the Stringent Response by Loading of RelA-tRNA Complexes at the Ribosomal A-Site.
Molecular Cell.
70.
2018
Novel (p)ppGpp Binding and Metabolizing Proteins of Escherichia coli.
mBio.
9.
2018
Ribosome Hibernation.
Annual Review of Genetics.
52.
2018
SLING: a tool to search for linked genes in bacterial datasets.
Nucleic Acids Research.
46.
2018
The kinases HipA and HipA7 phosphorylate different substrate pools in Escherichia coli to promote multidrug tolerance.
Science Signaling.
11.
2018
Toxins, Targets, and Triggers: An Overview of Toxin-Antitoxin Biology.
Molecular Cell.
70.
2018
HicA toxin of Escherichia coli derepresses hicAB transcription to selectively produce HicB antitoxin.
Molecular Microbiology.
104.
2017
Peptide‐nucleotide antibiotic Microcin C is a potent inducer of stringent response and persistence in both sensitive and producing cells.
Molecular Microbiology.
104.
2017
Prophages and Growth Dynamics Confound Experimental Results with Antibiotic-Tolerant Persister Cells.
mBio.
8.
2017
Ribosome-dependent Vibrio cholerae mRNAse HigB2 is regulated by a β-strand sliding mechanism.
Nucleic Acids Research.
45.
2017
Alarmone (p)ppGpp regulates the transition from pathogenicity to mutualism in Photorhabdus luminescens.
Molecular Microbiology.
100.
2016
Back to the Roots: Deep View into the Evolutionary History of ADP-Ribosylation Opened by the DNA-Targeting Toxin-Antitoxin Module DarTG.
Molecular Cell.
64.
2016
Hypothesis: type I toxin–antitoxin genes enter the persistence field—a feedback mechanism explaining membrane homoeostasis.
Philosophical Transactions of the Royal Society B Biological Sciences.
371.
2016
Mechanisms of bacterial persistence during stress and antibiotic exposure.
Science.
354.
2016
Pumping persisters.
Nature.
534.
2016
Rapid Curtailing of the Stringent Response by Toxin-Antitoxin Module-Encoded mRNases.
Journal of Bacteriology.
198.
2016
VapCs of Mycobacterium tuberculosis cleave RNAs essential for translation.
Nucleic Acids Research.
44.
2016
Adenylylation of Gyrase and Topo IV by FicT Toxins Disrupts Bacterial DNA Topology.
Cell Reports.
12.
2015
CRP‐dependent Positive Autoregulation and Proteolytic Degradation Regulate Competence Activator Sxy of Escherichia coli.
Molecular Microbiology.
95.
2015
Cell age dependent concentration of Escherichia coli divisome proteins analyzed with ImageJ and ObjectJ.
Frontiers in Microbiology.
6.
2015
Crystallization of two operator complexes from the Vibrio cholerae HigBA2 toxin–antitoxin module.
Acta Crystallographica Section F: Structural Biology Communications.
71.
2015
Recent functional insights into the role of (p)ppGpp in bacterial physiology.
Nature Reviews Microbiology.
13.
2015
Remarkable Functional Convergence: Alarmone ppGpp Mediates Persistence by Activating Type I and II Toxin-Antitoxins.
Molecular Cell.
59.
2015
Stochastic induction of persister cells by HipA through (p)ppGpp-mediated activation of mRNA endonucleases.
Proceedings of the National Academy of Sciences of the United States of America.
112.
2015
Competing ParA Structures Space Bacterial Plasmids Equally over the Nucleoid.
PLoS Computational Biology.
10.
2014
Molecular Mechanisms Underlying Bacterial Persisters.
Cell.
157.
2014
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chapter
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dataset
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Data_Sheet_1_CRP Interacts Specifically With Sxy to Activate Transcription in Escherichia coli.docx.
frontiers.
2019
Parameter values used in the diffusion/immobilization model..
public-library-of-science.
2014
Parameter values used in the directed motion models..
public-library-of-science.
2014
Reactions and propensities used in the diffusion/immobilization model..
public-library-of-science.
2014
Reactions and propensities used in the directed motion models..
public-library-of-science.
2014
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hide from search
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Conditional Cooperativity of Toxin - Antitoxin Regulation Can Mediate Bistability between Growth and Dormancy.
public-library-of-science.
2013
Reference parameter values..
public-library-of-science.
2013
Conditional Cooperativity of Toxin - Antitoxin Regulation Can Mediate Bistability between Growth and Dormancy.
PLoS Computational Biology.
2013
Crystallization of the HigBA2 toxin–antitoxin complex from Vibrio cholerae.
Acta Crystallographica Section F: Structural Biology Communications.
2013
Killing the survivors.
Nature.
2013
Protein expression, crystallization and preliminary X-ray crystallographic analysis of the isolated Shigella flexneri VapC toxin.
Acta Crystallographica Section F: Structural Biology Communications.
2013
VapC20 of Mycobacterium tuberculosis cleaves the Sarcin–Ricin loop of 23S rRNA.
Nature Communications.
2013
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preprint