selected publications
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academic article
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An NAD+-Dependent Sirtuin Depropionylase and Deacetylase (Sir2La) from the Probiotic Bacterium Lactobacillus acidophilus NCFM..
Biochemistry.
57.
2018
Histone Deacetylase 11 Is an ε-N-Myristoyllysine Hydrolase.
Cell Chemical Biology.
25.
2018
Chemical Editing of Macrocyclic Natural Products and Kinetic Profiling Reveal Slow, Tight-Binding Histone Deacetylase Inhibitors with Picomolar Affinities..
Biochemistry.
56.
2017
Frontispiece: Mechanism‐Based Inhibitors of the Human Sirtuin 5 Deacylase: Structure–Activity Relationship, Biostructural, and Kinetic Insight.
Angewandte Chemie International Edition.
56.
2017
Frontispiz: Mechanism‐Based Inhibitors of the Human Sirtuin 5 Deacylase: Structure–Activity Relationship, Biostructural, and Kinetic Insight.
Angewandte Chemie.
129.
2017
Mechanism‐Based Inhibitors of the Human Sirtuin 5 Deacylase: Structure–Activity Relationship, Biostructural, and Kinetic Insight.
Angewandte Chemie.
129.
2017
Mechanism‐Based Inhibitors of the Human Sirtuin 5 Deacylase: Structure–Activity Relationship, Biostructural, and Kinetic Insight.
Angewandte Chemie International Edition.
56.
2017
Metabolic control by sirtuins and other enzymes that sense NAD+, NADH, or their ratio.
Biochimica et Biophysica Acta (BBA) - Bioenergetics.
1858.
2017
SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion.
Cell Metabolism.
25.
2017
Scalable and Purification-Free Synthesis of a Myristoylated Fluorogenic Sirtuin Substrate.
Synlett.
28.
2017
A Continuous, Fluorogenic Sirtuin 2 Deacylase Assay: Substrate Screening and Inhibitor Evaluation..
Journal of Medicinal Chemistry.
59.
2016
A potent trifluoromethyl ketone histone deacetylase inhibitor exhibits class-dependent mechanism of action.
MedChemComm.
7.
2016
An acetylation photoswitch.
Nature Chemical Biology.
12.
2016
Innovative Strategies for Selective Inhibition of Histone Deacetylases.
Cell Chemical Biology.
23.
2016
Investigating the Sensitivity of NAD+-dependent Sirtuin Deacylation Activities to NADH.
Journal of Biological Chemistry.
291.
2016
An azumamide C analogue without the zinc-binding functionality.
MedChemComm.
5.
2014
Back Cover: The Effect of Various Zinc Binding Groups on Inhibition of Histone Deacetylases 1–11 (ChemMedChem 3/2014).
ChemMedChem.
9.
2014
Lysine Glutarylation Is a Protein Posttranslational Modification Regulated by SIRT5.
Cell Metabolism.
19.
2014
Recognition of double-stranded DNA using energetically activated duplexes with interstrand zippers of 1-, 2- or 4-pyrenyl-functionalized O 2′-alkylated RNA monomers.
Organic & Biomolecular Chemistry.
12.
2014
The Effect of Various Zinc Binding Groups on Inhibition of Histone Deacetylases 1–11.
ChemMedChem.
9.
2014
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dataset
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A Continuous, Fluorogenic
Sirtuin 2 Deacylase Assay: Substrate Screening and Inhibitor Evaluation.
american-chemical-society.
2016
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hide from search
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Identification and characterization of second-generation invader locked nucleic acids (LNAs) for mixed-sequence recognition of double-stranded DNA..
The Journal of Organic Chemistry.
2013
Effective Modulation of DNA Duplex Stability by Reversible
Transition Metal Complex Formation in the Minor Groove.
american-chemical-society.
2007
Effective Modulation of DNA Duplex Stability by Reversible
Transition Metal Complex Formation in the Minor Groove.
american-chemical-society.
2007
Effective Modulation of DNA Duplex Stability by Reversible
Transition Metal Complex Formation in the Minor Groove.
american-chemical-society.
2007
Effective Modulation of DNA Duplex Stability by Reversible
Transition Metal Complex Formation in the Minor Groove.
american-chemical-society.
2007
Synthesis and Hybridization Studies of 2‘-Amino-α-L-LNA and
Tetracyclic “Locked LNA”†.
american-chemical-society.
2006
Synthesis and Hybridization Studies of 2‘-Amino-α-L-LNA and
Tetracyclic “Locked LNA”†.
american-chemical-society.
2006
Synthesis and Hybridization Studies of 2‘-Amino-α-L-LNA and
Tetracyclic “Locked LNA”†.
american-chemical-society.
2006
Synthesis and Hybridization Studies of 2‘-Amino-α-L-LNA and
Tetracyclic “Locked LNA”†.
american-chemical-society.
2006
Synthesis and Hybridization Studies of 2‘-Amino-α-L-LNA and
Tetracyclic “Locked LNA”†.
american-chemical-society.
2006
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preprint
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Histone Deacetylase 11 is an ε-N-Myristoyllysine Hydrolase.
bioRxiv.
2017