selected publications
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academic article
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LEGO‐Inspired Drug Design: Unveiling a Class of Benzo[d]thiazoles Containing a 3,4‐Dihydroxyphenyl Moiety as Plasma Membrane H+‐ATPase Inhibitors.
ChemMedChem.
13.
2018
Nonlinear relationship between ER Ca2+ depletion versus induction of the unfolded protein response, autophagy inhibition, and cell death.
Cell Calcium.
76.
2018
Phorbol Rearrangements..
Journal of Natural Products.
81.
2018
Preparation of Enzyme-Activated Thapsigargin Prodrugs by Solid-Phase Synthesis.
Molecules.
23.
2018
Accelerating the Domestication of New Crops: Feasibility and Approaches.
Trends in Plant Science.
22.
2017
Cover Feature: Difluoroacetic Acid as a New Reagent for Direct C−H Difluoromethylation of Heteroaromatic Compounds (Chem. Eur. J. 72/2017).
Chemistry - A European Journal.
23.
2017
Cranberry Juice and Combinations of Its Organic Acids Are Effective against Experimental Urinary Tract Infection.
Frontiers in Microbiology.
8.
2017
Difluoroacetic Acid as a New Reagent for Direct C−H Difluoromethylation of Heteroaromatic Compounds.
Chemistry - A European Journal.
23.
2017
Fusaric acid and analogues as Gram-negative bacterial quorum sensing inhibitors.
European Journal of Medicinal Chemistry.
126.
2017
Inhibition of the sarco/endoplasmic reticulum (ER) Ca2+-ATPase by thapsigargin analogs induces cell death via ER Ca2+ depletion and the unfolded protein response.
Journal of Biological Chemistry.
292.
2017
Localization and in-Vivo Characterization of Thapsia garganica CYP76AE2 Indicates a Role in Thapsigargin Biosynthesis.
Plant Physiology.
174.
2017
Metformin, an Anthropogenic Contaminant of Seidlitzia rosmarinus Collected in a Desert Region near the Gulf of Aqaba, Sinai Peninsula..
Journal of Natural Products.
80.
2017
Structure/activity relationship of thapsigargin inhibition on the purified Golgi/secretory pathway Ca2+/Mn2+-transport ATPase (SPCA1a).
Journal of Biological Chemistry.
292.
2017
Demethoxycurcumin Is A Potent Inhibitor of P-Type ATPases from Diverse Kingdoms of Life.
PLoS ONE.
11.
2016
Iminolactones as tools for inversion of the absolute configuration of α-amino acids and as inhibitors of cancer cell proliferation.
European Journal of Medicinal Chemistry.
114.
2016
Are we ready for back-to-nature crop breeding?.
Trends in Plant Science.
20.
2015
Chemo- and Regioselective Functionalization of Nortrilobolide: Application for Semisynthesis of the Natural Product 2-Acetoxytrilobolide..
Journal of Natural Products.
78.
2015
Concise synthesis of thapsigargin from nortrilobolide.
Tetrahedron Letters.
56.
2015
Iminolactones from Schizophyllum commune..
Journal of Natural Products.
78.
2015
Targeting thapsigargin towards tumors.
Steroids.
97.
2015
Thapsigargin, Origin, Chemistry, Structure-Activity Relationships and Prodrug Development..
Current Pharmaceutical Design.
21.
2015
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chapter
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dataset
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Metformin, an Anthropogenic Contaminant of Seidlitzia rosmarinus Collected in a Desert Region near
the Gulf of Aqaba, Sinai Peninsula.
american-chemical-society.
2017
Demethoxycurcumin Is A Potent Inhibitor of P-Type ATPases from Diverse Kingdoms of Life.
public-library-of-science.
2016
Effect of DMCM on the ATP hydrolysis of the PM H+-ATPases..
public-library-of-science.
2016
Effects of compounds 1–3 on PM H+-ATPases in vitro and in in vivo drop test assay..
public-library-of-science.
2016
IC50 values for compounds 1–3 in ATP hydrolysis assays..
public-library-of-science.
2016
Iminolactones
from Schizophyllum commune.
american-chemical-society.
2015
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Differential effects of thapsigargin analogues on apoptosis of prostate cancer cells.
The FEBS Journal.
2013
Guaianolide Sesquiterpenoids: Pharmacology and Biosynthesis
2013
Serotonin transporter protein (SERT) and P-glycoprotein (P-gp) binding activity of montanine and coccinine from three species of Haemanthus L. (Amaryllidaceae).
South African Journal of Botany.
2013
Water-mediated interactions influence the binding of thapsigargin to sarco/endoplasmic reticulum calcium adenosinetriphosphatase..
Journal of Medicinal Chemistry.
2013
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patent