selected publications
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academic article
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A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer.
Nature Genetics.
50.
2018
An updated Alzheimer hypothesis: Complement C3 and risk of Alzheimer's disease—A cohort study of 95,442 individuals.
Alzheimer's & Dementia.
14.
2018
Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.
Nature Genetics.
50.
2018
Association of LPA Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies: A Mendelian Randomization Analysis.
JAMA Cardiology.
3.
2018
Blood eosinophil count and risk of pneumonia hospitalisations in individuals with COPD.
European Respiratory Journal.
51.
2018
Complement C3 and Risk of Diabetic Microvascular Disease: A Cohort Study of 95202 Individuals from the General Population..
Clinical Chemistry.
64.
2018
Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants.
Nature Communications.
9.
2018
Plasma urate, lung function and chronic obstructive pulmonary disease: a Mendelian randomisation study in 114 979 individuals from the general population.
Thorax.
73.
2018
Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts.
The BMJ.
360.
2018
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
Nature Genetics.
50.
2018
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
Nature Genetics.
50.
2018
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
Nature Genetics.
50.
2018
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
Nature Genetics.
50.
2018
Association analysis identifies 65 new breast cancer risk loci.
Nature.
551.
2017
Body mass index and breast cancer survival: a Mendelian randomization analysis.
International Journal of Epidemiology.
46.
2017
Exome-wide association study of plasma lipids in >300,000 individuals.
Nature Genetics.
49.
2017
Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms.
Nature Genetics.
49.
2017
Genetic invalidation of Lp-PLA2 as a therapeutic target: Large-scale study of five functional Lp-PLA2-lowering alleles.
European Journal of Preventive Cardiology.
24.
2017
Genetic variants affecting cross-sectional lung function in adults show little or no effect on longitudinal lung function decline.
Thorax.
72.
2017
Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
Nature Genetics.
49.
2017
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.
Nature Genetics.
49.
2017
Kringle IV Type 2, Not Low Lipoprotein(a), as a Cause of Diabetes: A Novel Genetic Approach Using SNPs Associated Selectively with Lipoprotein(a) Concentrations or with Kringle IV Type 2 Repeats..
Clinical Chemistry.
63.
2017
Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity.
Scientific Reports.
7.
2017
Rare and low-frequency coding variants alter human adult height.
Nature.
542.
2017
The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers.
Cancer Epidemiology Biomarkers & Prevention.
26.
2017
A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease.
Science Translational Medicine.
8.
2016
Blood Eosinophils and Exacerbations in Chronic Obstructive Pulmonary Disease. The Copenhagen General Population Study.
American Journal of Respiratory and Critical Care Medicine.
193.
2016
Complement C3 and High Risk of Venous Thromboembolism: 80517 Individuals from the Copenhagen General Population Study..
Clinical Chemistry.
62.
2016
Genetic variation in the immunosuppression pathway genes and breast cancer susceptibility: a pooled analysis of 42,510 cases and 40,577 controls from the Breast Cancer Association Consortium.
Human Genetics.
135.
2016
High alcohol consumption causes high IgE levels but not high risk of allergic disease.
Journal of Allergy and Clinical Immunology.
138.
2016
Morbidity and Mortality in 7,684 Women According to Personal Hair Dye Use: The Copenhagen City Heart Study followed for 37 Years.
PLoS ONE.
11.
2016
Negative statin-related news stories decrease statin persistence and increase myocardial infarction and cardiovascular mortality: a nationwide prospective cohort study.
European Heart Journal.
37.
2016
No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.
Gynecologic Oncology.
141.
2016
PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS.
Journal of Medical Genetics.
53.
2016
Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease.
Science.
351.
2016
Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.
Nature Genetics.
48.
2016
Common germline polymorphisms associated with breast cancer-specific survival.
Breast Cancer Research.
17.
2015
Fine-Scale Mapping of the 5q11.2 Breast Cancer Locus Reveals at Least Three Independent Risk Variants Regulating MAP3K1.
American Journal of Human Genetics.
96.
2015
Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2.
Human Molecular Genetics.
24.
2015
Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer.
Nature Genetics.
47.
2015
Height and Breast Cancer Risk: Evidence From Prospective Studies and Mendelian Randomization.
Journal of the National Cancer Institute.
107.
2015
Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk.
Human Molecular Genetics.
24.
2015
Identification of Novel Genetic Markers of Breast Cancer Survival.
Journal of the National Cancer Institute.
107.
2015
IgE and risk of cancer in 37 747 individuals from the general population.
Annals of Oncology.
26.
2015
In Reply..
Clinical Chemistry.
61.
2015
Increased Rheumatoid Factor and Deep Venous Thrombosis: 2 Cohort Studies of 54628 Individuals from the General Population.
Clinical Chemistry.
61.
2015
Inherited variants in the inner centromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER-negative breast cancer.
Carcinogenesis.
36.
2015
Investigation of gene‐environment interactions between 47 newly identified breast cancer susceptibility loci and environmental risk factors.
International Journal of Cancer.
136.
2015
Prediction of Breast Cancer Risk Based on Profiling With Common Genetic Variants.
Journal of the National Cancer Institute.
107.
2015
Statin Use Is Associated with Reduced Mortality in Patients with Interstitial Lung Disease.
PLoS ONE.
10.
2015
A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer.
Nature Genetics.
46.
2014
Antihypertensive treatment and risk of atrial fibrillation: a nationwide study.
European Heart Journal.
35.
2014
Authors’ Response to: Skin cancer as a marker of sun exposure—a case of serious immortality bias.
International Journal of Epidemiology.
43.
2014
Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation.
Nature Communications.
5.
2014
Genetic Predisposition to In Situ and Invasive Lobular Carcinoma of the Breast.
PLOS Genetics.
10.
2014
Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade.
Human Molecular Genetics.
23.
2014
Refined histopathological predictors of BRCA1 and BRCA2mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia.
Breast Cancer Research.
16.
2014
Statin use before diabetes diagnosis and risk of microvascular disease: a nationwide nested matched study.
The Lancet Diabetes & Endocrinology.
2.
2014
Susceptibility to Chronic Mucus Hypersecretion, a Genome Wide Association Study.
PLoS ONE.
9.
2014
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dataset
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Baseline characteristics of female participants according to personal use of hair dye..
public-library-of-science.
2016
Cancer according to personal use of hair dye during up to 36 years of follow-up in women from the general population..
public-library-of-science.
2016
Morbidity and Mortality in 7,684 Women According to Personal Hair Dye Use: The Copenhagen City Heart Study followed for 37 Years.
public-library-of-science.
2016
Morbidity leading to hospitalization, spirometrically chronic obstructive pulmonary disease, self-reported asthma, and hypersensitivity according to hair dye use during up to 37 years of follow-up..
public-library-of-science.
2016
Other major morbidities and all-cause mortality according to personal hair dye use during up to 37 years of follow-up in women from the general population..
public-library-of-science.
2016
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hide from search
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Causal and Synthetic Associations of Variants in the SERPINA Gene Cluster with Alpha1-antitrypsin Serum Levels.
public-library-of-science.
2013
Common and low-frequent SERPINA1 SNPs and their association with AAT serum level, univariate and conditional on significantly associated SNPs (N = 5569a), in SAPALDIA..
public-library-of-science.
2013
GUESS-ing Polygenic Associations with Multiple Phenotypes Using a GPU-Based Evolutionary Stochastic Search Algorithm.
public-library-of-science.
2013
Minor allele effects of PI S, PI Z and rs4905179 on AAT serum levels in the Copenhagen City Heart Study..
public-library-of-science.
2013
Minor allele effects on FEV1 of low-frequent and common SNPs in the SERPINA gene cluster in ever-smokers undergoing lung resection..
public-library-of-science.
2013
The ten most strongly associated SNPs in the GWAS on AAT serum level, conditional on PI S and PI Z alleles in SAPALDIA (N = 1392)..
public-library-of-science.
2013
The ten most strongly associated SNPs in the unconditional GWAS on AAT serum level in SAPALDIA (N = 1392)..
public-library-of-science.
2013
A genome-wide association scan (GWAS) for mean telomere length within the COGS project: identified loci show little association with hormone-related cancer risk.
Human Molecular Genetics.
2013
Causal and Synthetic Associations of Variants in the SERPINA Gene Cluster with Alpha1-antitrypsin Serum Levels.
PLOS Genetics.
2013
Fine-Scale Mapping of the FGFR2 Breast Cancer Risk Locus: Putative Functional Variants Differentially Bind FOXA1 and E2F1.
American Journal of Human Genetics.
2013
GUESS-ing Polygenic Associations with Multiple Phenotypes Using a GPU-Based Evolutionary Stochastic Search Algorithm.
PLOS Genetics.
2013
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer.
Nature Genetics.
2013
Skin cancer as a marker of sun exposure associates with myocardial infarction, hip fracture and death from any cause.
International Journal of Epidemiology.
2013
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