selected publications
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academic article
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A vaccine targeted specifically to prevent cerebral malaria – is there hope?.
Expert Review of Vaccines.
17.
2018
Antibodies to Intercellular Adhesion Molecule 1-Binding Plasmodium falciparum Erythrocyte Membrane Protein 1-DBLβ Are Biomarkers of Protective Immunity to Malaria in a Cohort of Young Children from Papua New Guinea.
Infection and Immunity.
86.
2018
Immunization with Recombinant Plasmodium falciparum Erythrocyte Membrane Protein 1 CIDRα1 Domains Induces Domain Subtype Inhibitory Antibodies.
Infection and Immunity.
86.
2018
Cellulose filtration of blood from malaria patients for improving ex vivo growth of Plasmodium falciparum parasites.
Malaria Journal.
16.
2017
Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors.
Nature.
552.
2017
Parasites Causing Cerebral Falciparum Malaria Bind Multiple Endothelial Receptors and Express EPCR and ICAM-1-Binding PfEMP1.
The Journal of Infectious Diseases.
215.
2017
Plasmodium falciparum EPCR-binding PfEMP1 expression increases with malaria disease severity and is elevated in retinopathy negative cerebral malaria.
BMC Medicine.
15.
2017
Structure-Guided Identification of a Family of Dual Receptor-Binding PfEMP1 that Is Associated with Cerebral Malaria.
Cell Host & Microbe.
21.
2017
The Severity of Plasmodium falciparum Infection Is Associated with Transcript Levels of var Genes Encoding Endothelial Protein C Receptor-Binding P. falciparum Erythrocyte Membrane Protein 1.
Infection and Immunity.
85.
2017
Towards an anti-disease malaria vaccine.
Emerging Topics in Life Sciences.
1.
2017
Adhesion of Plasmodium falciparum infected erythrocytes in ex vivo perfused placental tissue: a novel model of placental malaria.
Malaria Journal.
15.
2016
Breaking down brain barrier breaches in cerebral malaria.
Journal of Clinical Investigation.
126.
2016
Cytoadhesion to gC1qR through Plasmodium falciparum Erythrocyte Membrane Protein 1 in Severe Malaria.
PLoS Pathogens.
12.
2016
Differences in PfEMP1s recognized by antibodies from patients with uncomplicated or severe malaria.
Malaria Journal.
15.
2016
Plasma Ang2 and ADAM17 levels are elevated during clinical malaria; Ang2 level correlates with severity and expression of EPCR-binding PfEMP1.
Scientific Reports.
6.
2016
Plasmodium falciparum Plasmodium helical interspersed subtelomeric proteins contribute to cytoadherence and anchor P. falciparum erythrocyte membrane protein 1 to the host cell cytoskeleton.
Cellular Microbiology.
18.
2016
Plasmodium falciparum var genes expressed in children with severe malaria encode CIDRα1 domains.
EMBO Molecular Medicine.
8.
2016
The endothelial protein C receptor rs867186-GG genotype is associated with increased soluble EPCR and could mediate protection against severe malaria.
Scientific Reports.
6.
2016
The role of EPCR in the pathogenesis of severe malaria.
Thrombosis Research.
141.
2016
The structural basis for CD36 binding by the malaria parasite.
Nature Communications.
7.
2016
Haplotypes of the endothelial protein C receptor (EPCR) gene are not associated with severe malaria in Tanzania.
Malaria Journal.
14.
2015
IgG Antibodies to Endothelial Protein C Receptor-Binding Cysteine-Rich Interdomain Region Domains of Plasmodium falciparum Erythrocyte Membrane Protein 1 Are Acquired Early in Life in Individuals Exposed to Malaria.
Infection and Immunity.
83.
2015
Protein C system defects inflicted by the malaria parasite protein PfEMP1 can be overcome by a soluble EPCR variant..
Thrombosis and Haemostasis.
114.
2015
Structural Conservation Despite Huge Sequence Diversity Allows EPCR Binding by the PfEMP1 Family Implicated in Severe Childhood Malaria.
Cell Host & Microbe.
17.
2015
DNA secondary structures are associated with recombination in major Plasmodium falciparum variable surface antigen gene families.
Nucleic Acids Research.
42.
2014
Disruption of EPCR-Dependent Functions By Plasmodium Falciparum Erythrocyte Membrane Protein 1 (PfEMP1) Can be Rescued By a Soluble EPCR Variant.
Blood.
124.
2014
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Additional file 1 of Immunization with virus-like particles conjugated to CIDRα1 domain of Plasmodium falciparum erythrocyte membrane protein 1 induces inhibitory antibodies.
springer-nature.
2020
Early gametocytes of the malaria parasite Plasmodium falciparum specifically remodel the adhesive properties of infected erythrocyte surface.
Cellular Microbiology.
2013
Expression of the Domain Cassette 8 Plasmodium falciparum Erythrocyte Membrane Protein 1 Is Associated with Cerebral Malaria in Benin.
PLoS ONE.
2013
Malaria's deadly grip: cytoadhesion of Plasmodium falciparum‐infected erythrocytes.
Cellular Microbiology.
2013
PfSETvs methylation of histone H3K36 represses virulence genes in Plasmodium falciparum.
Nature.
2013
Plasmodium falciparum Expressing Domain Cassette 5 Type PfEMP1 (DC5-PfEMP1) Bind PECAM1.
PLoS ONE.
2013
Severe malaria is associated with parasite binding to endothelial protein C receptor.
Nature.
2013
Plasmodium falciparum Erythrocyte Membrane Protein 1 Diversity in Seven Genomes – Divide and Conquer.
public-library-of-science.
2010
Confirmation by real-time quantitative rt-PCR of in vivo expression of mRNA for 13 different genes, compared with that in 3D7 in vitro reference..
public-library-of-science.
2008
Plasmodium falciparum Transcriptome Analysis Reveals Pregnancy Malaria Associated Gene Expression.
public-library-of-science.
2008
Total number of genes that were differentially expressed in in vivo parasite isolates compared with expression in in vitro 3D7 reference..
public-library-of-science.
2008
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