selected publications
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academic article
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A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.
American Journal of Human Genetics.
102.
2018
Analysis of shared heritability in common disorders of the brain.
Science.
360.
2018
Consortium-based genome-wide meta-analysis for childhood dental caries traits..
Human Molecular Genetics.
27.
2018
Dairy Consumption and Body Mass Index Among Adults: Mendelian Randomization Analysis of 184802 Individuals from 25 Studies.
Clinical Chemistry.
64.
2018
Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6.
Genome Biology.
19.
2018
Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.
American Journal of Human Genetics.
103.
2018
Meta-analysis of exome array data identifies six novel genetic loci for lung function.
Wellcome Open Research.
3.
2018
Multi-ethnic genome-wide association study for atrial fibrillation.
Nature Genetics.
50.
2018
Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.
Nature Genetics.
50.
2018
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.
PLoS ONE.
13.
2018
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
Nature Genetics.
50.
2018
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
Nature Genetics.
50.
2018
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
Nature Genetics.
50.
2018
A Low-Frequency Inactivating Akt2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk..
Diabetes.
66.
2017
Discovery of novel heart rate-associated loci using the Exome Chip.
Human Molecular Genetics.
26.
2017
Genetic Interactions with Age, Sex, Body Mass Index, and Hypertension in Relation to Atrial Fibrillation: The AFGen Consortium.
Scientific Reports.
7.
2017
Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity.
Nature Communications.
8.
2017
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.
Nature Communications.
8.
2017
Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults.
PLOS Genetics.
13.
2017
Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function.
Journal of Clinical Investigation.
127.
2017
Rare and low-frequency coding variants alter human adult height.
Nature.
542.
2017
SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function.
Journal of the American Society of Nephrology.
28.
2017
52 Genetic Loci Influencing Myocardial Mass.
Journal of the American College of Cardiology.
68.
2016
A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape.
Nature Communications.
7.
2016
Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits.
American Journal of Human Genetics.
99.
2016
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.
Nature Genetics.
48.
2016
Genome-wide analysis identifies 12 loci influencing human reproductive behavior.
Nature Genetics.
48.
2016
Genome-wide associations for birth weight and correlations with adult disease.
Nature.
538.
2016
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.
Nature Communications.
7.
2016
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine.
Nature Genetics.
48.
2016
Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium.
Behavior Genetics.
46.
2016
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.
Nature Communications.
7.
2016
Ophthalmic epidemiology in Europe: the “European Eye Epidemiology” (E3) consortium.
European Journal of Epidemiology.
31.
2016
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.
Nature Genetics.
48.
2016
Directional dominance on stature and cognition in diverse human populations.
Nature.
523.
2015
Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation.
PLOS Genetics.
11.
2015
Genetic studies of body mass index yield new insights for obesity biology.
Nature.
518.
2015
Is the adiposity‐associated FTO gene variant related to all‐cause mortality independent of adiposity? Meta‐analysis of data from 169,551 Caucasian adults.
Obesity Reviews.
16.
2015
Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder.
JAMA Psychiatry.
72.
2015
New genetic loci link adipose and insulin biology to body fat distribution.
Nature.
518.
2015
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
PLOS Genetics.
11.
2015
The impact of low-frequency and rare variants on lipid levels.
Nature Genetics.
47.
2015
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.
Nature Genetics.
47.
2015
Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study.
The Lancet Diabetes & Endocrinology.
2.
2014
Defining the role of common variation in the genomic and biological architecture of adult human height.
Nature Genetics.
46.
2014
FTO genetic variants, dietary intake and body mass index: insights from 177 330 individuals.
Human Molecular Genetics.
23.
2014
Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.
Nature Genetics.
46.
2014
Harmonization of Neuroticism and Extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium: an application of Item Response Theory.
Behavior Genetics.
44.
2014
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dataset
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Additional file 1: of Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6.
springer-nature.
2018
Novel SNVs/Genes associated with BP traits from correlated meta-analysis in European ancestry in Stage 1..
public-library-of-science.
2018
Novel SNVs/Genes associated with BP traits in European ancestry..
public-library-of-science.
2018
Novel SNVs/Genes associated with BP traits in European ancestry..
public-library-of-science.
2018
Novel SNVs/Genes associated with BP traits in Multi-ancestry meta-analysis in combined Stage 1 and Stage 2..
public-library-of-science.
2018
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.
public-library-of-science.
2018
Potential novel SNVs/Genes associated with BP traits in African ancestry..
public-library-of-science.
2018
Genes of biological interest within 500 kb of lead SNPs associated with BMI..
public-library-of-science.
2017
Genes of biological interest within 500 kb of lead SNPs associated with WCadjBMI or WHRadjBMI..
public-library-of-science.
2017
Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults.
public-library-of-science.
2017
Novel loci achieving genome-wide significance (P<5x10-8) in meta-analyses for PA-adjusted SNP main effect (PadjPA) or the joint test of SNP main effect and SNP-PA interaction (Pjoint)..
public-library-of-science.
2017
Association signals for glycaemic and obesity-related traits for which the 99% credible sets contain no more than 20 variants..
public-library-of-science.
2015
Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation.
public-library-of-science.
2015
Enrichment analyses using look-up data for the 15 age-group specific BMI loci..
public-library-of-science.
2015
Fifteen BMI loci showing significant age-differences in adults ≤50y compared to adults >50y..
public-library-of-science.
2015
Forty-four WHRadjBMI loci showing significant sex-differences..
public-library-of-science.
2015
Loci with multiple distinct signals of association with glycaemic and obesity-related traits achieving “locus-wide” significance in conditional analysis (pCOND<10−5)..
public-library-of-science.
2015
Novel loci for glycaemic and obesity-related traits achieving genome-wide significance (p<5x10-8)..
public-library-of-science.
2015
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
public-library-of-science.
2015
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hide from search
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Common variants associated with plasma triglycerides and risk for coronary artery disease.
Nature Genetics.
2013
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
Nature Genetics.
2013
Genome-wide meta-analysis identifies new susceptibility loci for migraine.
Nature Genetics.
2013
Identification of heart rate–associated loci and their effects on cardiac conduction and rhythm disorders.
Nature Genetics.
2013
Lipoprotein Subclass Profiling Reveals Pleiotropy in the Genetic Variants of Lipid Risk Factors for Coronary Heart Disease A Note on Mendelian Randomization Studies.
Journal of the American College of Cardiology.
2013
Mendelian Randomization Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes.
Diabetes.
2013
New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism.
Nature Genetics.
2013
Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits.
PLOS Genetics.
2013
A Genome-Wide Screen for Interactions Reveals a New Locus on 4p15 Modifying the Effect of Waist-to-Hip Ratio on Total Cholesterol.
public-library-of-science.
2011
Association of the minor (A−) allele of the rs9939609 SNP or a proxy (r2>0.8) in the FTO gene with BMI, waist circumference, body fat percentage, risk of obesity, and risk of overweight in a random effects meta-analysis of up to 218,166 adults..
public-library-of-science.
2011
Effect of the interaction between the rs9939609 SNP or a proxy (r2>0.8) and PA on BMI, waist circumference, body fat percentage, risk of obesity, and risk of overweight in a random effects meta-analysis of up to 218,166 adults..
public-library-of-science.
2011
Physical Activity Attenuates the Influence of FTO Variants on Obesity Risk: A Meta-Analysis of 218,166 Adults and 19,268 Children.
public-library-of-science.
2011
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preprint