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Cross, Simon S

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• , University of Sheffield
• , Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK (NM, PDPP, KM, MKB, QW, JD, RL, JBr, DFE); Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK (PDPP, JT, AMD, MS, CL, CB, SA, MM, CSH, DFE); Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK (MNB, ASw, MJS); Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Denmark (SEB, BGN, SFN); Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Herlev, Denmark (SEB, BGN, SFN); Faculty of Health and Medical Sciences, Copenhagen University Hospital, Copenhagen, Herlev, Denmark (SEB, BGN); Department of Breast Surgery, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Herlev, Denmark (HF); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (KC, HD, ME, KH, PHa); Department of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK (JP, IdSS, FD); Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK (NJ, AA, NO, MGC); Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam, the Netherlands (MKS, AB, SV, EJR); Division of Breast Cancer Research, Institute of Cancer Research, London, UK (ASw); Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD (JF, SJC, LB, ASi, MD); Department of Cancer Epidemiology and Prevention, M. Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland (JLis); Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN (FJC); Department of Health Sciences Research, Mayo Clinic, Rochester, MN (JEO, CV, VSP, SS); Vesalius Research Center, VIB, Leuven, Belgium (DL); Laboratory for Translational Genetics, Department of Oncology, University of
• , Department of Neuroscience, University of Sheffield, Royal Hallamshire Hospital, Sheffield S10 2JF, UK

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Publications

selected publications

• academic article

  A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer.  Nature Genetics.  50. 2018
  The BRCA2 c.68‐7T > A variant is not pathogenic: A model for clinical calibration of spliceogenicity.  Human Mutation.  39. 2018
  Association analysis identifies 65 new breast cancer risk loci.  Nature.  551. 2017
  BRCA2 Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer.  Cancer Research.  77. 2017
  Body mass index and breast cancer survival: a Mendelian randomization analysis.  International Journal of Epidemiology.  46. 2017
  Genetic modifiers of CHEK2*1100delC-associated breast cancer risk.  Genetics in Medicine.  19. 2017
  Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.  Nature Genetics.  49. 2017
  Reproductive profiles and risk of breast cancer subtypes: a multi-center case-only study.  Breast Cancer Research.  19. 2017
  Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation.  American Journal of Human Genetics.  99. 2016
  Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs).  Scientific Reports.  6. 2016
  Fine-Mapping of the 1p11.2 Breast Cancer Susceptibility Locus.  PLoS ONE.  11. 2016
  Genetic variation in the immunosuppression pathway genes and breast cancer susceptibility: a pooled analysis of 42,510 cases and 40,577 controls from the Breast Cancer Association Consortium.  Human Genetics.  135. 2016
  Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent.  PLoS Medicine.  13. 2016
  Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer.  Nature Communications.  7. 2016
  No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.  Gynecologic Oncology.  141. 2016
  No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: implications for gene panel testing.  Journal of Medical Genetics.  53. 2016
  RAD51B in Familial Breast Cancer.  PLoS ONE.  11. 2016
  Common germline polymorphisms associated with breast cancer-specific survival.  Breast Cancer Research.  17. 2015
  Fine-Scale Mapping of the 4q24 Locus Identifies Two Independent Loci Associated with Breast Cancer Risk.  Cancer Epidemiology Biomarkers & Prevention.  24. 2015
  Fine-Scale Mapping of the 5q11.2 Breast Cancer Locus Reveals at Least Three Independent Risk Variants Regulating MAP3K1.  American Journal of Human Genetics.  96. 2015
  Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2.  Human Molecular Genetics.  24. 2015
  Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer.  Nature Genetics.  47. 2015
  Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk.  Human Molecular Genetics.  24. 2015
  Identification of Novel Genetic Markers of Breast Cancer Survival.  Journal of the National Cancer Institute.  107. 2015
  Inherited variants in the inner centromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER-negative breast cancer.  Carcinogenesis.  36. 2015
  Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 Expression.  American Journal of Human Genetics.  97. 2015
  Prediction of Breast Cancer Risk Based on Profiling With Common Genetic Variants.  Journal of the National Cancer Institute.  107. 2015
  SNP-SNP interaction analysis of NF-κB signaling pathway on breast cancer survival.  Oncotarget.  6. 2015
  Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation.  Nature Communications.  5. 2014
  Genetic Predisposition to In Situ and Invasive Lobular Carcinoma of the Breast.  PLOS Genetics.  10. 2014
  Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study.  Breast Cancer Research.  16. 2014
  Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade.  Human Molecular Genetics.  23. 2014
  Refined histopathological predictors of BRCA1 and BRCA2mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia.  Breast Cancer Research.  16. 2014

• dataset

  Associations between genetically predicted BMI and breast cancer risk..  public-library-of-science. 2016
  Associations of the weighted BMI-GSs with BMI and traditional breast cancer risk factors..  public-library-of-science. 2016
  Estimated haplotype frequencies and haplotype-specific ORs among the BCAC dataset..  public-library-of-science. 2016
  Fine-Mapping of the 1p11.2 Breast Cancer Susceptibility Locus.  public-library-of-science. 2016
  Frequencies and ORs for the SNPs rs2588809, rs1314913, and rs999737 for all breast cancer cases, familial cases and ER-positive and -negative cases in the BCAC dataset..  public-library-of-science. 2016
  Frequencies and ORs for the c.541C>T mutation among the different patient subgroups in the Helsinki, Tampere, Oulu, and Belarus series..  public-library-of-science. 2016
  Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent.  public-library-of-science. 2016
  RAD51B in Familial Breast Cancer.  public-library-of-science. 2016
  Significant associations detected at p < 0.05 between breast cancer risk and BMI-related SNPs..  public-library-of-science. 2016
  Two independent association signals at the 1p11.2 locus: Association results for breast cancer risk among European women in BCAC, by tumor characteristic..  public-library-of-science. 2016
  Two independent association signals at the 1p11.2 locus: Association results for breast cancer risk among women in BCAC, by ancestry..  public-library-of-science. 2016
  Variants identified in the screening of the RAD51B gene (RefSeq NM_133509.3)..  public-library-of-science. 2016

• hide from search

  Association of haplotypes composed of rs2046210 and rs12662670 with breast cancer..  public-library-of-science. 2012
  Association of rs2046210 and rs12662670 with breast cancer..  public-library-of-science. 2012
  Association of rs2046210 and rs12662670 with risk of ER−*/ER+** breast cancer..  public-library-of-science. 2012
  Comparison of 6q25 Breast Cancer Hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC).  public-library-of-science. 2012
  Heterogeneity of Breast Cancer Associations with Five Susceptibility Loci by Clinical and Pathological Characteristics.  public-library-of-science. 2008
  Multivariate Cox proportional hazards analysis of genetic polymorphisms in relation to overall survival following breast cancer diagnosis, by ER status*..  public-library-of-science. 2008
  Odds ratios for breast cancer risk by lymph node involvement*..  public-library-of-science. 2008
  Odds ratios for breast cancer risk by tumor grade*..  public-library-of-science. 2008
  Per-allele odds ratios for breast cancer risk by estrogen receptor status..  public-library-of-science. 2008

Contact

full name

• Simon S Cross