Rades, Thomas

Evaluation of the effects of spray drying parameters for producing cubosome powder precursors

A non-destructive method for quality control of the pellet distribution within a MUPS tablet by terahertz pulsed imaging

A platform for preparing homogeneous proteinaceous sub-visible particles with distinct morphologies

Application of a Salt Coformer in a Co-Amorphous Drug System Dramatically Enhances the Glass Transition Temperature: A Case Study of the Ternary System Carbamazepine, Citric Acid, and l-Arginine.

Are phytosomes a superior nanodelivery system for the antioxidant rutin?

Aspartame as a co-former in co-amorphous systems

Characterisation of pore structures of pharmaceutical tablets: A review

Characterization of the Hydrodynamics in a Miniaturized Dissolution Apparatus

Combining diagnostic methods for antimicrobial susceptibility testing – A comparative approach

Comparison of two DSC-based methods to predict drug-polymer solubility

Development and characterization of clove oil nanoemulsions and self-microemulsifying drug delivery systems

Drug nanocrystallisation within liposomes

Effect of amorphous phase separation and crystallization on the in vitro and in vivo performance of an amorphous solid dispersion

Effect of composition of simulated intestinal media on the solubility of poorly soluble compounds investigated by design of experiments

Formulation of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine and Kolliphor® RH40 using experimental design

Glass-Transition Temperature of the β-Relaxation as the Major Predictive Parameter for Recrystallization of Neat Amorphous Drugs.

Immune responses induced by nano-self-assembled lipid adjuvants based on a monomycoloyl glycerol analogue after vaccination with the Chlamydia trachomatis major outer membrane protein

In situ co-amorphisation of arginine with indomethacin or furosemide during immersion in an acidic medium – a proof of concept study

In vitro and in vivo comparison between crystalline and co-amorphous salts of naproxen-arginine

Induction of Cytotoxic T-Lymphocyte Responses Upon Subcutaneous Administration of a Subunit Vaccine Adjuvanted With an Emulsion Containing the Toll-Like Receptor 3 Ligand Poly(I:C)

Influence of Solvent Composition on the Performance of Spray-Dried Co-Amorphous Formulations

Influence of preparation technique on co-amorphization of carvedilol with acidic amino acids

Is there a correlation between the glass forming ability of a drug and its supersaturation propensity?

On the role of salt formation and structural similarity of co-formers in co-amorphous drug delivery systems

Organic acids as co-formers for co-amorphous systems - influence of variation in molar ratio on the physicochemical properties of the co-amorphous systems

Quantification of microwave-induced amorphization of celecoxib in PVP tablets using transmission Raman spectroscopy

Spray dried cubosomes with ovalbumin and Quil-A as a nanoparticulate dry powder vaccine formulation

The Influence of Polymers on the Supersaturation Potential of Poor and Good Glass Formers

The Role of Glass Transition Temperatures in Coamorphous Drug-Amino Acid Formulations.

The ability of two in vitro lipolysis models reflecting the human and rat gastro-intestinal conditions to predict the in vivo performance of SNEDDS dosing regimens

The use of molecular descriptors in the development of co-amorphous formulations

Toward quality assessment of 3D printed oral dosage forms

Ultrasensitive Microstring Resonators for Solid State Thermomechanical Analysis of Small and Large Molecules.

Undesired co-amorphisation of indomethacin and arginine during combined storage at high humidity conditions

Using Potentiometric Free Drug Sensors to Determine the Free Concentration of Ionizable Drugs in Colloidal Systems

Amorphization within the tablet: Using microwave irradiation to form a glass solution in situ

Amorphous is not always better—A dissolution study on solid state forms of carbamazepine

Analysis of 3D Prints by X-ray Computed Microtomography and Terahertz Pulsed Imaging

Development of a Video-Microscopic Tool To Evaluate the Precipitation Kinetics of Poorly Water Soluble Drugs: A Case Study with Tadalafil and HPMC.

High-Throughput Lipolysis in 96-Well Plates for Rapid Screening of Lipid-Based Drug Delivery Systems

Hot Melt Extrusion and Spray Drying of Co-amorphous Indomethacin-Arginine With Polymers

Importance of in vitro dissolution conditions for the in vivo predictability of an amorphous solid dispersion containing a pH-sensitive carrier

Improvement of the physicochemical properties of Co-amorphous naproxen-indomethacin by naproxen-sodium

In vitro and in vivo performance of monoacyl phospholipid-based self-emulsifying drug delivery systems

Influence of drug load and physical form of cinnarizine in new SNEDDS dosing regimens: in vivo and in vitro evaluations

Influence of preparation pathway on the glass forming ability

Interdependence of Dosage Form Microstructure and Performance

Investigation of the Intra- and Interlaboratory Reproducibility of a Small Scale Standardized Supersaturation and Precipitation Method.

Melt Extrusion of High-Dose Co-Amorphous Drug-Drug Combinations

Microcontainers as an oral delivery system for spray dried cubosomes containing ovalbumin

Monoacyl phosphatidylcholine inhibits the formation of lipid multilamellar structures during in vitro lipolysis of self-emulsifying drug delivery systems

Multispectral UV Imaging for Determination of the Tablet Coating Thickness

Nanomechanical Infrared Spectroscopy with Vibrating Filters for Pharmaceutical Analysis

Performance comparison between crystalline and co-amorphous salts of indomethacin-lysine

Probing Pharmaceutical Mixtures during Milling: The Potency of Low-Frequency Raman Spectroscopy in Identifying Disorder.

Self-microemulsifying drug delivery system and nanoemulsion for enhancing aqueous miscibility of Alpinia galanga oil

Solid state properties and drug release behavior of co-amorphous indomethacin-arginine tablets coated with Kollicoat® Protect

Supersaturating drug delivery systems: The potential of co-amorphous drug formulations

Systematic Investigation of the Role of Surfactant Composition and Choice of oil: Design of a Nanoemulsion-Based Adjuvant Inducing Concomitant Humoral and CD4+ T-Cell Responses

The significance of the amorphous potential energy landscape for dictating glassy dynamics and driving solid-state crystallisation

UV imaging of multiple unit pellet system (MUPS) tablets: A case study of acetylsalicylic acid stability

A Promising New Method to Estimate Drug-Polymer Solubility at Room Temperature

Anhydrate to hydrate solid-state transformations of carbamazepine and nitrofurantoin in biorelevant media studied in situ using time-resolved synchrotron X-ray diffraction

Comparison of lipases for in vitro models of gastric digestion: lipolysis using two infant formulas as model substrates

Correction: Formation of drug nanocrystals under nanoconfinement afforded by liposomes

Corrigendum to “Formulation and characterization of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine” [Int. J. Pharm. 502 (1–2) (2016) 151–160]

Development of a screening method for co-amorphous formulations of drugs and amino acids

Effect of polymer type and drug dose on the in vitro and in vivo behavior of amorphous solid dispersions

Formation of drug nanocrystals under nanoconfinement afforded by liposomes

Formulation and characterization of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine

Glass Forming Ability of Amorphous Drugs Investigated by Continuous Cooling and Isothermal Transformation.

Glass solution formation in water - In situ amorphization of naproxen and ibuprofen with Eudragit® E PO

In Situ Lipolysis and Synchrotron Small‐Angle X‐ray Scattering for the Direct Determination of the Precipitation and Solid‐State Form of a Poorly Water‐Soluble Drug During Digestion of a Lipid‐Based Formulation

In Vivo Precipitation of Poorly Soluble Drugs from Lipid-Based Drug Delivery Systems.

Influence of Copolymer Composition on In Vitro and In Vivo Performance of Celecoxib-PVP/VA Amorphous Solid Dispersions

Influence of PVP/VA copolymer composition on drug–polymer solubility

Influence of polymer molecular weight on in vitro dissolution behavior and in vivo performance of celecoxib:PVP amorphous solid dispersions

Influence of the cooling rate and the blend ratio on the physical stability of co-amorphous naproxen/indomethacin

Influence of variation in molar ratio on co-amorphous drug-amino acid systems

Inhalable Antimicrobials for Treatment of Bacterial Biofilm-Associated Sinusitis in Cystic Fibrosis Patients: Challenges and Drug Delivery Approaches

Interlaboratory Validation of Small-Scale Solubility and Dissolution Measurements of Poorly Water-Soluble Drugs

Investigation of physical properties and stability of indomethacin–cimetidine and naproxen–cimetidine co‐amorphous systems prepared by quench cooling, coprecipitation and ball milling

Lipid-Based Formulations Can Enable the Model Poorly Water-Soluble Weakly Basic Drug Cinnarizine To Precipitate in an Amorphous-Salt Form During In Vitro Digestion.

Liposome-Based Adjuvants for Subunit Vaccines: Formulation Strategies for Subunit Antigens and Immunostimulators

Multispectral UV imaging for fast and non-destructive quality control of chemical and physical tablet attributes

Multispectral UV imaging for surface analysis of MUPS tablets with special focus on the pellet distribution

Polymeric microcontainers improve oral bioavailability of furosemide

Preparation and characterization of spray‐dried co‐amorphous drug–amino acid salts

Preparation and recrystallization behavior of spray-dried co-amorphous naproxen–indomethacin

Properties of the Sodium Naproxen-Lactose-Tetrahydrate Co-Crystal upon Processing and Storage

Rapid Assessment of Tablet Film Coating Quality by Multispectral UV Imaging

Recent advances and potential applications of modulated differential scanning calorimetry (mDSC) in drug development

Recent advances in co-amorphous drug formulations

Solvent free amorphisation for pediatric formulations (minitablets) using mesoporous silica

Statistical Analysis of a Method to Predict Drug–Polymer Miscibility

Studying the Propensity of Compounds to Supersaturate: A Practical and Broadly Applicable Approach

Supersaturation of zafirlukast in fasted and fed state intestinal media with and without precipitation inhibitors

The Effect of Digestion and Drug Load on Halofantrine Absorption from Self-nanoemulsifying Drug Delivery System (SNEDDS)

The Precipitation Behavior of Poorly Water-Soluble Drugs with an Emphasis on the Digestion of Lipid Based Formulations

The administration route is decisive for the ability of the vaccine adjuvant CAF09 to induce antigen-specific CD8+ T-cell responses: The immunological consequences of the biodistribution profile

The effect of surfactants on the dissolution behavior of amorphous formulations

The influence of co-formers on the dissolution rates of co-amorphous sulfamerazine/excipient systems

Unintended and in situ amorphisation of pharmaceuticals

Anti-Ageing Effects of Sonchus oleraceus L. (pūhā) Leaf Extracts on H2O2-Induced Cell Senescence

Characterization of Amorphous and Co-Amorphous Simvastatin Formulations Prepared by Spray Drying

Comparative Study of Different Methods for the Prediction of Drug-Polymer Solubility.

Development of a high-throughput in vitro intestinal lipolysis model for rapid screening of lipid-based drug delivery systems

Differential scanning calorimetry predicts the critical quality attributes of amorphous glibenclamide

Elucidating the Molecular Interactions Occurring during Drug Precipitation of Weak Bases from Lipid-Based Formulations: A Case Study with Cinnarizine and a Long Chain Self-Nanoemulsifying Drug Delivery System.

Evaluation of Drug–Polymer Solubility Curves Through Formal Statistical Analysis: Comparison of Preparation Techniques

Formation Mechanism of Coamorphous Drug-Amino Acid Mixtures.

Image Analytical Approach for Needle-Shaped Crystal Counting and Length Estimation

Improvement of dissolution rate of indomethacin by inkjet printing

Influence of Polymer Molecular Weight on Drug–Polymer Solubility: A Comparison between Experimentally Determined Solubility in PVP and Prediction Derived from Solubility in Monomer

Influence of Tableting on the Conformation and Thermal Stability of Trypsin as a Model Protein

Lysozyme–magnesium aluminum silicate microparticles: Molecular interaction, bioactivity and release studies

Modified thermoresponsive Poloxamer 407 and chitosan sol–gels as potential sustained-release vaccine delivery systems

Multivariate Quantification of the Solid State Phase Composition of Co-Amorphous Naproxen-Indomethacin

Polymer incorporation method affects the physical stability of amorphous indomethacin in aqueous suspension

Predicting Crystallization of Amorphous Drugs with Terahertz Spectroscopy.

Simple measurements for prediction of drug release from polymer matrices – Solubility parameters and intrinsic viscosity

Solid-state properties and dissolution behaviour of tablets containing co-amorphous indomethacin–arginine

Stabilisation of amorphous furosemide increases the oral drug bioavailability in rats

Synthesis, Formulation, and Adjuvanticity of Monodesmosidic Saponins with Olenanolic Acid, Hederagenin and Gypsogenin Aglycones, and some C‐28 Ester Derivatives

Use of low-frequency Raman spectroscopy and chemometrics for the quantification of crystallinity in amorphous griseofulvin tablets

pH-triggered drug release from biodegradable microwells for oral drug delivery

A slow cooling rate of indomethacin melt spatially confined in microcontainers increases the physical stability of the amorphous drug without influencing its biorelevant dissolution behaviour

Activation of the NLRP3 inflammasome is not a feature of all particulate vaccine adjuvants

Acute oral administration of lauric acid reduces energy intake in healthy males

Amino acids as co-amorphous excipients for simvastatin and glibenclamide: physical properties and stability.

Application of spray-drying and electrospraying/electospinning for poorly water-soluble drugs: a particle engineering approach.

Chemical imaging and solid state analysis at compact surfaces using UV imaging

Current advances and future trends in characterizing poorly water-soluble drugs using spectroscopic, imaging and data analytical techniques.

Distribution of binder in granules produced by means of twin screw granulation

Improving co-amorphous drug formulations by the addition of the highly water soluble amino Acid, proline.

In Vitro Lipolysis Data Does Not Adequately Predict the In Vivo Performance of Lipid-Based Drug Delivery Systems Containing Fenofibrate

Influence of postharvest processing and storage conditions on key antioxidants in pūhā (Sonchus oleraceus L.)

Physical characterization of synthetic phosphatidylinositol dimannosides and analogues in binary systems with phosphatidylcholine.

Refining stability and dissolution rate of amorphous drug formulations

The Influence of Pressure on the Intrinsic Dissolution Rate of Amorphous Indomethacin

Unravelling the relationship between degree of disorder and the dissolution behavior of milled glibenclamide.

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Rades, Thomas

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