selected publications
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academic article
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17q21 variant increases the risk of exacerbations in asthmatic children despite inhaled corticosteroids use.
Allergy.
73.
2018
Author Correction: Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.
Nature Genetics.
50.
2018
Budesonide/formoterol maintenance and reliever therapy in adolescent patients with asthma.
European Respiratory Journal.
51.
2018
Cadherin-related Family Member 3 Genetics and Rhinovirus C Respiratory Illnesses.
American Journal of Respiratory and Critical Care Medicine.
197.
2018
Cat exposure in early life decreases asthma risk from the 17q21 high-risk variant.
Journal of Allergy and Clinical Immunology.
141.
2018
Consortium-based genome-wide meta-analysis for childhood dental caries traits..
Human Molecular Genetics.
27.
2018
Data representations and -analyses of binary diary data in pursuit of stratifying children based on common childhood illnesses.
PLoS ONE.
13.
2018
Effect of fish oil supplementation in pregnancy on bone, lean, and fat mass at six years: randomised clinical trial.
The BMJ.
362.
2018
Environmental grass pollen levels in utero and at birth and cord blood IgE: Analysis of three birth cohorts.
Environment International.
119.
2018
Epidemiology and Risk Factors of Infection in Early Childhood.
Pediatrics.
141.
2018
FeNO and Exercise Testing in Children at Risk of Asthma.
The Journal of Allergy and Clinical Immunology In Practice.
6.
2018
Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.
Nature Genetics.
50.
2018
Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics..
Human Molecular Genetics.
27.
2018
Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects.
American Journal of Human Genetics.
102.
2018
Limited clinical value of exhaled volatile organic compound measurements in childhood asthma.
ERJ Open Research.
4.
2018
Maturation of the gut microbiome and risk of asthma in childhood.
Nature Communications.
9.
2018
Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.
Nature Genetics.
50.
2018
NKG2D gene variation and susceptibility to viral bronchiolitis in childhood.
Pediatric Research.
84.
2018
Neonates colonized with pathogenic bacteria in the airways have a low‐grade systemic inflammation.
Allergy.
73.
2018
Prenatal Vitamin D Supplementation to Improve Health in Offspring.
JAMA Pediatrics.
172.
2018
Safety and efficacy of tiotropium in children aged 1–5 years with persistent asthmatic symptoms: a randomised, double-blind, placebo-controlled trial.
The Lancet Respiratory Medicine.
6.
2018
Short- and long-term impacts of azithromycin treatment on the gut microbiota in children: A double-blind, randomized, placebo-controlled trial.
EBioMedicine.
38.
2018
A functional IFN-λ4-generating DNA polymorphism could protect older asthmatic women from aeroallergen sensitization and associate with clinical features of asthma.
Scientific Reports.
7.
2017
A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma.
PLOS Genetics.
13.
2017
Allergic sensitization at school age is a systemic low‐grade inflammatory disorder.
Allergy.
72.
2017
Antibiotics in Pregnancy Increase Children's Risk of Otitis Media and Ventilation Tubes.
The Journal of Pediatrics.
183.
2017
Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus.
Nature Communications.
8.
2017
CDHR3 gene variation and childhood bronchiolitis.
Journal of Allergy and Clinical Immunology.
140.
2017
Cesarean Delivery and Body Mass Index at 6 Months and Into Childhood.
Pediatrics.
139.
2017
Fish Oil in Pregnancy and Asthma in Offspring..
New England Journal of Medicine.
376.
2017
In utero exposure to 25-hydroxyvitamin D and risk of childhood asthma, wheeze, and respiratory tract infections: A meta-analysis of birth cohort studies.
Journal of Allergy and Clinical Immunology.
139.
2017
Investigating the causal effect of smoking on hay fever and asthma: a Mendelian randomization meta-analysis in the CARTA consortium.
Scientific Reports.
7.
2017
Knemometry is more sensitive to systemic effects of inhaled corticosteroids in children with asthma than 24-hour urine cortisol excretion.
Journal of Allergy and Clinical Immunology.
140.
2017
No evidence of intrauterine sensitization against inhalant allergens.
Journal of Allergy and Clinical Immunology.
140.
2017
Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels..
Journal of Visualized Experiments.
2017
Precision allergy: Separate allergies to male and female dogs.
The Journal of Allergy and Clinical Immunology In Practice.
5.
2017
Preeclampsia Associates with Asthma, Allergy, and Eczema in Childhood.
American Journal of Respiratory and Critical Care Medicine.
195.
2017
Prenatal vitamin D supplementation reduces risk of asthma/recurrent wheeze in early childhood: A combined analysis of two randomized controlled trials.
PLoS ONE.
12.
2017
Rationale and design of the multiethnic Pharmacogenomics in Childhood Asthma consortium.
Pharmacogenomics.
18.
2017
Sensitization trajectories in childhood revealed by using a cluster analysis.
Journal of Allergy and Clinical Immunology.
140.
2017
Shared genetic variants suggest common pathways in allergy and autoimmune diseases.
Journal of Allergy and Clinical Immunology.
140.
2017
4th Pediatric Allergy and Asthma Meeting (PAAM).
Clinical and Translational Allergy.
6.
2016
A genome-wide association meta-analysis of diarrhoeal disease in young children identifies FUT2 locus and provides plausible biological pathways..
Human Molecular Genetics.
25.
2016
Atopic endotype in childhood.
Journal of Allergy and Clinical Immunology.
137.
2016
Azithromycin for episodes with asthma-like symptoms in young children aged 1–3 years: a randomised, double-blind, placebo-controlled trial.
The Lancet Respiratory Medicine.
4.
2016
Blood lipid levels associate with childhood asthma, airway obstruction, bronchial hyperresponsiveness, and aeroallergen sensitization.
Journal of Allergy and Clinical Immunology.
137.
2016
Cesarean section changes neonatal gut colonization.
Journal of Allergy and Clinical Immunology.
138.
2016
Chronic Chlamydia pneumoniae lung infection: a neglected explanation for macrolide effects in wheezing and asthma? – Authors' reply.
The Lancet Respiratory Medicine.
4.
2016
Current concepts in chronic inflammatory diseases: Interactions between microbes, cellular metabolism, and inflammation.
Journal of Allergy and Clinical Immunology.
138.
2016
Divergent response profile in activated cord blood T cells from first‐born child implies birth‐order‐associated in utero immune programming.
Allergy.
71.
2016
Domestic dog exposure at birth reduces the incidence of atopic dermatitis.
Allergy.
71.
2016
Early growth characteristics and the risk of reduced lung function and asthma: A meta-analysis of 25,000 children.
Journal of Allergy and Clinical Immunology.
137.
2016
Early indoor aeroallergen exposure is not associated with development of sensitization or allergic rhinitis in high‐risk children.
Allergy.
71.
2016
Effect of Vitamin D3 Supplementation During Pregnancy on Risk of Persistent Wheeze in the Offspring: A Randomized Clinical Trial.
JAMA.
315.
2016
Fish Oil–Derived Fatty Acids in Pregnancy and Wheeze and Asthma in Offspring.
New England Journal of Medicine.
375.
2016
Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight.
JAMA.
315.
2016
Genetic associations with viral respiratory illnesses and asthma control in children.
Clinical & Experimental Allergy.
46.
2016
Genetic variants linked to education predict longevity.
Proceedings of the National Academy of Sciences of the United States of America.
113.
2016
Genome-wide analysis identifies 12 loci influencing human reproductive behavior.
Nature Genetics.
48.
2016
Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index.
Human Molecular Genetics.
25.
2016
Genome-wide association study identifies 74 loci associated with educational attainment.
Nature.
533.
2016
Genome-wide associations for birth weight and correlations with adult disease.
Nature.
538.
2016
High breast milk IL‐1β level is associated with reduced risk of childhood eczema.
Clinical & Experimental Allergy.
46.
2016
Incidence and Determinants of Ventilation Tubes in Denmark.
PLoS ONE.
11.
2016
Large-scale benchmarking reveals false discoveries and count transformation sensitivity in 16S rRNA gene amplicon data analysis methods used in microbiome studies.
Microbiome.
4.
2016
New time-saving predictor algorithm for multiple breath washout in adolescents.
Pediatric Research.
80.
2016
Picornavirus-Induced Airway Mucosa Immune Profile in Asymptomatic Neonates.
The Journal of Infectious Diseases.
213.
2016
Reply.
Journal of Allergy and Clinical Immunology.
138.
2016
Risk of Asthma from Cesarean Delivery Depends on Membrane Rupture.
The Journal of Pediatrics.
171.
2016
Season of birth shapes neonatal immune function.
Journal of Allergy and Clinical Immunology.
137.
2016
Siblings Promote a Type 1/Type 17‐oriented immune response in the airways of asymptomatic neonates.
Allergy.
71.
2016
Stable admission rate for acute asthma in Danish children since 1977.
European Journal of Epidemiology.
31.
2016
Susceptibility to Lower Respiratory Infections in Childhood is Associated with Perturbation of the Cytokine Response to Pathogenic Airway Bacteria.
The Pediatric Infectious Disease Journal.
35.
2016
The developing hypopharyngeal microbiota in early life.
Microbiome.
4.
2016
17q21 gene variation is not associated with asthma in adulthood.
Allergy.
70.
2015
A novel common variant in DCST2 is associated with length in early life and height in adulthood.
Human Molecular Genetics.
24.
2015
Airway Mucosal Immune-suppression in Neonates of Mothers Receiving A(H1N1)pnd09 Vaccination During Pregnancy.
The Pediatric Infectious Disease Journal.
34.
2015
Association between respiratory infections in early life and later asthma is independent of virus type.
Journal of Allergy and Clinical Immunology.
136.
2015
Breast-feeding does not protect against allergic sensitization in early childhood and allergy-associated disease at age 7 years.
Journal of Allergy and Clinical Immunology.
136.
2015
Cesarean Section and Chronic Immune Disorders.
Pediatrics.
135.
2015
Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort.
European Respiratory Journal.
46.
2015
DENND1B gene variants associate with elevated exhaled nitric oxide in healthy high‐risk neonates.
Pediatric Pulmonology.
50.
2015
Directional dominance on stature and cognition in diverse human populations.
Nature.
523.
2015
Disagreement between skin prick test and specific IgE in young children.
Allergy.
70.
2015
Duration of wheezy episodes in early childhood is independent of the microbial trigger.
Journal of Allergy and Clinical Immunology.
136.
2015
Maternal fatty acid desaturase genotype correlates with infant immune responses at 6 months.
British Journal Of Nutrition.
114.
2015
Metagenomic heterogeneity explains dual immune effects of endotoxins.
Journal of Allergy and Clinical Immunology.
135.
2015
Neonates with reduced neonatal lung function have systemic low-grade inflammation.
Journal of Allergy and Clinical Immunology.
135.
2015
Postmenopausal hormone therapy and asthma-related hospital admission.
Journal of Allergy and Clinical Immunology.
135.
2015
Prelabor cesarean section bypasses natural immune cell maturation.
Journal of Allergy and Clinical Immunology.
136.
2015
The burden of severe asthma in childhood and adolescence: results from the paediatric U-BIOPRED cohorts.
European Respiratory Journal.
46.
2015
The gut microbiota and inflammatory noncommunicable diseases: Associations and potentials for gut microbiota therapies.
Journal of Allergy and Clinical Immunology.
135.
2015
The systemic exposure to inhaled beclometasone/formoterol pMDI with valved holding chamber is independent of age and body size.
Pulmonary Pharmacology & Therapeutics.
30.
2015
A clinical pharmacology study of fixed vs. free combination of inhaled beclometasone dipropionate and formoterol fumarate dry powder inhalers in asthmatic adolescents.
British Journal of Clinical Pharmacology.
78.
2014
A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations.
Nature Genetics.
46.
2014
Antibiotic use during pregnancy alters the commensal vaginal microbiota.
Clinical Microbiology and Infection.
20.
2014
Children with asthma by school age display aberrant immune responses to pathogenic airway bacteria as infants.
Journal of Allergy and Clinical Immunology.
133.
2014
Cord Blood 25(OH)-Vitamin D Deficiency and Childhood Asthma, Allergy and Eczema: The COPSAC2000 Birth Cohort Study.
PLoS ONE.
9.
2014
Effect of delivery device on systemic exposure to inhaled fluticasone propionate in children with asthma.
British Journal of Clinical Pharmacology.
78.
2014
Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants.
Journal of Allergy and Clinical Immunology.
134.
2014
Immune‐mediated diseases and microbial exposure in early life.
Clinical & Experimental Allergy.
44.
2014
Maternal propensity for infections and risk of childhood asthma: a registry-based cohort study.
The Lancet Respiratory Medicine.
2.
2014
Prenatal and postnatal genetic influence on lung function development.
Journal of Allergy and Clinical Immunology.
134.
2014
Preterm birth, infant weight gain, and childhood asthma risk: A meta-analysis of 147,000 European children.
Journal of Allergy and Clinical Immunology.
133.
2014
Systemic exposure to inhaled beclometasone/formoterol DPI is age and body size dependent.
Respiratory Medicine.
108.
2014
The PCDH1 gene and asthma in early childhood..
European Respiratory Journal.
43.
2014
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dataset
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A number of possible methods that can be used given the specific representation of the raw data..
public-library-of-science.
2018
Small example of a frequency table with patterns and diaries..
public-library-of-science.
2018
Top five terms for each of the four topics found by LDA..
public-library-of-science.
2018
Additional file 14: Table S2. of Large-scale benchmarking reveals false discoveries and count transformation sensitivity in 16S rRNA gene amplicon data analysis methods used in microbiome studies.
springer-nature.
2016
Additional file 1: Table S1. of Large-scale benchmarking reveals false discoveries and count transformation sensitivity in 16S rRNA gene amplicon data analysis methods used in microbiome studies.
springer-nature.
2016
Additional file 2: Figure S2. of The developing hypopharyngeal microbiota in early life.
springer-nature.
2016
Additional file 3: Figure S2. of Large-scale benchmarking reveals false discoveries and count transformation sensitivity in 16S rRNA gene amplicon data analysis methods used in microbiome studies.
springer-nature.
2016
Additional file 4: Figure S3. of Large-scale benchmarking reveals false discoveries and count transformation sensitivity in 16S rRNA gene amplicon data analysis methods used in microbiome studies.
springer-nature.
2016
Additional file 5: Figure S4. of Large-scale benchmarking reveals false discoveries and count transformation sensitivity in 16S rRNA gene amplicon data analysis methods used in microbiome studies.
springer-nature.
2016
Additional file 7: Figure S6. of Large-scale benchmarking reveals false discoveries and count transformation sensitivity in 16S rRNA gene amplicon data analysis methods used in microbiome studies.
springer-nature.
2016
Additional file 8: Figure S7. of Large-scale benchmarking reveals false discoveries and count transformation sensitivity in 16S rRNA gene amplicon data analysis methods used in microbiome studies.
springer-nature.
2016
Additional file 9: Figure S8. of Large-scale benchmarking reveals false discoveries and count transformation sensitivity in 16S rRNA gene amplicon data analysis methods used in microbiome studies.
springer-nature.
2016
Baseline characteristics of children with and without available cord blood for 25(OH)-Vitamin D analysis..
public-library-of-science.
2014
Cord blood 25(OH)-Vitamin D vs. allergic outcomes and eczema at 0–7 yrs..
public-library-of-science.
2014
Cord blood 25(OH)-Vitamin D vs. asthma-related outcomes, lower respiratory tract infections and lung function..
public-library-of-science.
2014
Data S1 - Cord Blood 25(OH)-Vitamin D Deficiency and Childhood Asthma, Allergy and Eczema: The COPSAC2000 Birth Cohort Study.
public-library-of-science.
2014
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hide from search
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Baseline characteristics for the entire cohort (N=696) and for the stratified group of women giving birth vaginally (N=545)..
public-library-of-science.
2013
Baseline characteristics..
public-library-of-science.
2013
Cat and dog and the vaginal colonization, oral antibiotic use and UTI in pregnancy..
public-library-of-science.
2013
Cochran-Armitage trend test for socio-economic variables; maternal educational level and household annual income..
public-library-of-science.
2013
Demographic characteristics for the entire cohort and grouped according to administration of UTI antibiotics and RTI antibiotics during pregnancy..
public-library-of-science.
2013
Prevalence of antibiotic administration during pregnancy, 706 women..
public-library-of-science.
2013
Association between whole-blood polyunsaturated fatty acids in pregnant women and early fetal weight.
European Journal of Clinical Nutrition.
2013
Deep phenotyping of the unselected COPSAC2010 birth cohort study.
Clinical & Experimental Allergy.
2013
Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.
Human Molecular Genetics.
2013
Increased Risk of Pneumonia and Bronchiolitis after Bacterial Colonization of the Airways as Neonates.
American Journal of Respiratory and Critical Care Medicine.
2013
Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization.
Nature Genetics.
2013
Objective assessment of levels and patterns of physical activity in preschool children.
Pediatric Research.
2013
Pathogenic Bacteria Colonizing the Airways in Asymptomatic Neonates Stimulates Topical Inflammatory Mediator Release.
American Journal of Respiratory and Critical Care Medicine.
2013
Prevalence and Predictors of Antibiotic Administration during Pregnancy and Birth.
PLoS ONE.
2013
Public Hygiene Campaign in Denmark during the 2009 H1N1 Pandemic Had No Effect on Hospitalization Rate of Communicable Diseases in Children.
PLoS ONE.
2013
Use of Antibiotics during Pregnancy Increases the Risk of Asthma in Early Childhood.
The Journal of Pediatrics.
2013
VEGFA variants are associated with pre‐school lung function, but not neonatal lung function.
Clinical & Experimental Allergy.
2013
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patent
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preprint
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Consortium genome-wide meta-analysis for childhood dental caries traits.
bioRxiv.
2017
Effect modification of FADS2 polymorphisms on the association between breastfeeding and intelligence: results from a collaborative meta-analysis.
bioRxiv.
2017
Genome-wide association study of offspring birth weight in 86,577 women highlights maternal genetic effects that are independent of fetal genetics.
bioRxiv.
2015